Oregon is currently home to 1217 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography
NCT00532051
Recruiting
The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases. OCT is well known for its exquisite resolution, but until recently it has not had sufficient speed to capture the shape of the cornea because of eye motion during OCT scanning. The development of Fourier-domain (FD) OCT technology has made the requisite speed possible. The objective of this project is to develop methods for imaging the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Casey Eye Institute, Oregon Health & Science University, Portland, Oregon
Conditions: Cataract
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Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study
NCT05633602
Recruiting
This phase III trial compares the effect of the combination of ramucirumab and pembrolizumab versus standard of care chemotherapy for the treatment of non-small cell lung cancer that is stage IV or that has come back after a period of improvement (recurrent). Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may in... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Legacy Mount Hood Medical Center, Gresham, Oregon
Conditions: Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
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DMSO Cryopreserved Platelets in Cardiopulmonary Bypass Surgery (CRYPTICS)
NCT04709705
Recruiting
A randomized, parallel group, active comparator-controlled trial to evaluate the non-inferiority or superiority of Cryopreserved Platelets with Liquid Stored Platelets in controlling blood loss in patients undergoing Cardiopulmonary Bypass Surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Cardiac Surgery
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The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Legacy Health, Portland, Oregon
Conditions: Burn Injury
Register for Updates
A Study of AT-02 in Subjects With Systemic Amyloidosis.
NCT05951049
Recruiting
This is a Phase 2 open-label extension study to evaluate the long-term safety, tolerability, and clinical activity of AT-02. AT-02 is an investigational medicinal product being developed to treat systemic amyloidosis.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/29/2024
Locations: OHSU (Oregon Health & Science University), Portland, Oregon
Conditions: Amyloidosis; Systemic
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Subscapularis Repair in Reverse Shoulder Arthroplasty
NCT05438914
Recruiting
This study will evaluate the subscapularis repair versus non-repair during a reverse shoulder arthroplasty (RSA).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
01/29/2024
Locations: Southern Oregon Orthopedics, Medford, Oregon
Conditions: Rotator Cuff Tear Arthropathy
Register for Updates
Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC)
NCT04938609
Recruiting
The purpose of this study is to evaluate the efficacy of neoadjuvant immunoradiotherapy (NIRT) prior to surgery for the treatment of stage III and IVA HPV- HNSCC.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Portland Providence Medical Center, Portland, Oregon
Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
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A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)
NCT03592472
Recruiting
This is a randomized, Phase 3, double-blind, placebo-controlled study of pazopanib plus abexinostat versus pazopanib plus placebo in patients with locally advanced unresectable or metastatic renal cell carcinoma (RCC).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Renal Cell Carcinoma
Register for Updates
Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias
NCT01013714
Recruiting
The purpose of this research study is to examine the effect of cardiac sympathetic denervation (CSD) surgery on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death. Subjects will be asked to participate in this research study if they have recurrent ventricular tachycardia (at least one ICD shock for ventricular tachycardia) and have undergone at least one catheter ablation procedure or have ventricular tachycard... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: OHSU, Portland, Oregon
Conditions: Sudden Cardiac Death, Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy
Register for Updates
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study
NCT04343313
Recruiting
The study is a prospective, multi-center, single-arm, non-randomized, Early Feasibility Study (EFS) to evaluate the safety and performance of the Half Moon TMVr System in patients with severe, symptomatic mitral regurgitation, who are at high risk for conventional mitral valve surgery.
Gender:
All
Ages:
Between 21 years and 95 years
Trial Updated:
01/10/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Mitral Valve Insufficiency
Register for Updates
Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults
NCT05822466
Recruiting
To examine two different exercise programs in reducing incidence of falls among community-dwelling older adults
Gender:
All
Ages:
Between 65 years and 90 years
Trial Updated:
01/05/2024
Locations: Oregon Research Institute, Springfield, Oregon
Conditions: Accidental Fall
Register for Updates
Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE)
NCT03707743
Recruiting
The aim of the study is to evaluate results of patients treated with the STABILISE technique for acute/subacute aortic dissection. Results and postoperative events are reported in accordance with the current reporting standards for endovascular aortic repair prepared and revised by the Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular Surgery/American Association for Vascular Surgery
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Providence Heart and Vascular Institute, Portland, Oregon
Conditions: Aortic Dissection
Register for Updates