Oregon is currently home to 1212 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
EASE: The Materna Prep Pivotal Study
NCT03973281
Recruiting
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device d... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Vaginal Delivery, Pelvic Organ Prolapse
Register for Updates
Supported Employment COVID-19 Rapid Testing for PWID
NCT05984966
Recruiting
This community-engaged project aims to improve the accessibility of rapid tests through a supported employment program for people who inject drugs (PWID). The program is called Peer Connect2Test (PeerC2T). PWID will be recruited by a community partner who provides syringe exchange services. PWID will the trained by the community partner to become peer health workers (PHW) to distribute SARS-CoV-2 rapid tests to other PWID. Investigators expect that PeerC2T will improve knowledge, self-efficacy,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: University of Oregon, Eugene, Oregon
Conditions: Health Behavior
Register for Updates
Post-Approval Study of the TREO Abdominal Stent-Graft System
NCT04697784
Recruiting
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Oregon Health and Sciences University, Portland, Oregon
Conditions: Abdominal Aortic Aneurysm
Register for Updates
Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination
NCT05859490
Recruiting
The goal of this clinical trial is to assess the immune response to the yellow fever vaccine 17D in adults with prior 17D vaccination. The main questions this study aims to answer are: * how does prior vaccination affect antibody responses to re-vaccination? * how does prior vaccination affect the immune cell response to re-vaccination? Participants will: * have been previously vaccinated with 17D. * be re-vaccinated with 17D. * provide medical and travel histories. * provide a blood sample p... Read More
Gender:
ALL
Ages:
Between 20 years and 49 years
Trial Updated:
09/26/2023
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Yellow Fever, Immunization; Infection
Register for Updates
Whole Genome Sequencing (WGS) on IVF Embryos and Individual Patients
NCT05739890
Recruiting
This research project aims to utilise recent advances in whole genome sequencing of preimplantation genetic diagnosis embryos to investigate the impact of paternal age on de novo mutation rates in IVF embryos. Embryos that are deemed unsuitable for transfer following preimplantation genetic testing for monogenic/single gene disorders (PGT-M) due to the detection of genetic abnormalities will be utilized for this study. These embryos will undergo re-biopsy, and both the biopsied samples as well a... Read More
Gender:
ALL
Ages:
Between 18 years and 48 years
Trial Updated:
09/21/2023
Locations: ORM Fertility, Portland, Oregon
Conditions: Fertility Issues, Single-Gene Defects
Register for Updates
Resilience, Grit, and Stress in Medical Students
NCT06046183
Recruiting
The incidence of burnout and mental ill-health begins very early in medical school and continues to be high throughout training. Medical students are under high amounts of stress, which often becomes chronic, and can lead to both physical and psychological issues as a student, resident, and physician. Chronic stress and burnout in medical students are not a new phenomenon, but recent research has highlighted the worsening mental health of medical students, with as high as three-quarters of stude... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/13/2023
Locations: Western University of Health Science, College of Osteopathic Medicine of the Pacific - Northwest, Lebanon, Oregon
Conditions: Stress, Psychological
Register for Updates
Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia
NCT04373941
Recruiting
The Investigators propose to test the hypothesis that GCSF enhances the clinical outcome of biliary atresia in a multi-institutional Phase 2 trial to prospectively evaluate the safety and efficacy of GCSF in each of the 2 groups of newly diagnosed BA patients: KBA (i.e., Kasai-operated) or NoK (i.e., patients who did not undergo Kasai surgery). Subjects who participate in the trial will be followed for 2 years.
Gender:
ALL
Ages:
Between 14 days and 180 days
Trial Updated:
09/07/2023
Locations: Oregon Health & Science University (OHSU), Portland, Oregon
Conditions: Biliary Atresia
Register for Updates
A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception
NCT04143659
Recruiting
This is a Phase I multicenter, open-label, dose-ranging, three-dose PK and PD study of injectable LB administered as an IM or SQ injection at 40 mg, and subsequently at 50mg SQ and then 60 mg SQ depending on the preliminary pharmacokinetic and pharmacodynamic results obtained with 40 mg dosing.
Gender:
FEMALE
Ages:
Between 18 years and 40 years
Trial Updated:
08/11/2023
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Healthy Women, Female Contraception
Register for Updates
A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
NCT03547115
Recruiting
This is a Phase 1, open-label, dose escalation study to determine the safety and preliminary efficacy of voruciclib monotherapy in subjects with relapsed/refractory B cell malignancies or AML after failure of standard therapies or voruciclib in combination with venetoclax in subjects with relapsed or refractory AML
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Small Lymphocytic Lymphoma (SLL), Chronic Lymphocytic Leukemia (CLL), Diffuse Large B-cell Lymphoma (DLBCL), Acute Myeloid Leukemia (AML)
Register for Updates
Non-Invasive At-Home Sleep Therapy System
NCT05970276
Recruiting
The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in healthy adults via home use sleep therapy device (SleepWISP). Participants will be asked to wear non-invasive and painless devices that record their brain activity during sleep. The clinical trial aims to answer the following main questions: 1. Whether the non-invasive transcranial electrical stimulation (TES) delivere... Read More
Gender:
ALL
Ages:
Between 22 years and 85 years
Trial Updated:
07/31/2023
Locations: Brain Electrophysiology Laboratory Company, Eugene, Oregon
Conditions: Sleep, Sleep Duration, Sleep Quality
Register for Updates
Total Shoulder Arthroplasty Multi-Center Registry
NCT03511586
Recruiting
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/27/2023
Locations: Not set, Medford, Oregon
Conditions: Shoulder Arthroplasty
Register for Updates
Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
NCT05902520
Recruiting
The subject of this study is the adoptive transfer of selected autologous tumor infiltrating lymphocytes (TIL) after in vitro expansion for the treatment of solid tumor malignancies. The TIL selection process is based on evidence showing that CD8+ TIL which co-express both CD39 and CD103 harbor the bulk of tumor-reactivity and that the remaining CD8 TIL is mainly composed of non-tumor reactive bystander cells. All of the expanded TIL that are produced (1-40 billion are expected) will be delivere... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Providence Portland Medical Center, Portland, Oregon
Conditions: HNSCC, Melanoma, Gynecologic Cancer, Colorectal Cancer, Lung Cancer, Urogenital Cancer
Register for Updates