Oregon is currently home to 1214 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography
NCT00532051
Recruiting
The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases. OCT is well known for its exquisite resolution, but until recently it has not had sufficient speed to capture the shape of the cornea because of eye motion during OCT scanning. The development of Fourier-domain (FD) OCT technology has made the requisite speed possible. The objective of this project is to develop methods for imaging the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Casey Eye Institute, Oregon Health & Science University, Portland, Oregon
Conditions: Cataract
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The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Legacy Health, Portland, Oregon
Conditions: Burn Injury
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Subscapularis Repair in Reverse Shoulder Arthroplasty
NCT05438914
Recruiting
This study will evaluate the subscapularis repair versus non-repair during a reverse shoulder arthroplasty (RSA).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/29/2024
Locations: Southern Oregon Orthopedics, Medford, Oregon
Conditions: Rotator Cuff Tear Arthropathy
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Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias
NCT01013714
Recruiting
The purpose of this research study is to examine the effect of cardiac sympathetic denervation (CSD) surgery on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death. Subjects will be asked to participate in this research study if they have recurrent ventricular tachycardia (at least one ICD shock for ventricular tachycardia) and have undergone at least one catheter ablation procedure or have ventricular tachycard... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: OHSU, Portland, Oregon
Conditions: Sudden Cardiac Death, Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy
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The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study
NCT04343313
Recruiting
The study is a prospective, multi-center, single-arm, non-randomized, Early Feasibility Study (EFS) to evaluate the safety and performance of the Half Moon TMVr System in patients with severe, symptomatic mitral regurgitation, who are at high risk for conventional mitral valve surgery.
Gender:
ALL
Ages:
Between 21 years and 95 years
Trial Updated:
01/10/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Mitral Valve Insufficiency
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Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults
NCT05822466
Recruiting
To examine two different exercise programs in reducing incidence of falls among community-dwelling older adults
Gender:
ALL
Ages:
Between 65 years and 90 years
Trial Updated:
01/05/2024
Locations: Oregon Research Institute, Springfield, Oregon
Conditions: Accidental Fall
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Coflex PS3 Actual Conditions for Use Study
NCT02555280
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Southern Oregon Orthpaedics, Medford, Oregon
Conditions: Spinal Stenosis Lumbar
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A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
NCT04775485
Recruiting
FIREFLY-1 is an ongoing, Phase 2, multi center, open-label study to evaluate the safety and efficacy of oral pan-RAF inhibitor DAY101 in pediatric, adolescent, and young adult patients with recurrent or progressive low-grade glioma or an advanced solid tumor harboring a known RAF alteration.
Gender:
ALL
Ages:
Between 6 months and 25 years
Trial Updated:
12/21/2023
Locations: Doernbecher Children's Hospital Oregon & Health Science University, Portland, Oregon
Conditions: Low-grade Glioma, Advanced Solid Tumor
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A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT03941379
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Oregon Health & Science University Casey Eye Institute, Portland, Oregon
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
Register for Updates
Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors
NCT04987112
Recruiting
To evaluate CAN1012(Selective TLR7 agonist) when administered by IT injection to subjects with advanced solid tumors who are not candidates for standard therapy.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/18/2023
Locations: Providence Cancer Institute, Portland, Oregon
Conditions: Solid Tumor, Cancer Metastatic
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Oregon PrEP at Home Study
NCT05949203
Recruiting
This demonstration study will evaluate the real-world implementation of long-acting cabotegravir (CAB-LA) for HIV pre-exposure prevention (PrEP) through a partnership between the OHSU Tele-PrEP Program (TPP) and the OHSU Home Infusion Pharmacy (HIP). The study will perform a formative evaluation of the TPP/HIP partnership to determine its merit and worth, with revisions made as needed to improve the program, which is reflective of a real-world program rollout. The study is observational, and the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: HIV/AIDS
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Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
NCT05705505
Recruiting
This study will assess the safety and efficacy of increasing doses of narazaciclib (ON 123300) in combination with the standard daily dose (2.5mg) of letrozole in patients with Recurrent Metastatic Low-grade Endometrioid Endometrial Cancer and other Gynecologic Malignancies.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Willamette Valley Cancer Institute and Research Center, Eugene, Oregon
Conditions: Endometrioid Endometrial Cancer
Register for Updates