Cyclophosphamide Treatment Options in Canada

A collection of 300 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the Canada . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

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A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation

NCT06045806

Active Not Recruiting

The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Local Institution - 0131, Los Angeles, California +100 locations

Local Institution - 0131, Los Angeles, California

Local Institution - 0126, Orange, California

Local Institution - 0113, Sacramento, California

Colorado Blood Cancer Institute, Denver, Colorado

Yale University School of Medicine, New Haven, Connecticut

AdventHealth Orlando, Orlando, Florida

Local Institution - 0121, Atlanta, Georgia

Local Institution - 0104, Atlanta, Georgia

Local Institution - 0151, Boston, Massachusetts

Ascension Providence Hospital, Southfield, Michigan

M Health Fairview Clinics and Surgery Center, Minneapolis, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Columbia University Irving Medical Center, New York, New York

Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Local Institution - 0132, Philadelphia, Pennsylvania

Local Institution - 0124, Austin, Texas

Local Institution - 0109, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 0007, Camperdown, New South Wales

Local Institution - 0005, Brisbane, Queensland

Local Institution - 0004, Melbourne, Victoria

Local Institution - 0006, Melbourne, Victoria

Local Institution - 0008, Melbourne, Victoria

Local Institution - 0011, Murdoch, Western Australia

Local Institution - 0089, Salzburg, Not set

Local Institution - 0090, Wien, Not set

Local Institution - 0083, Anderlecht, Bruxelles-Capitale, Région De

Local Institution - 0084, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0144, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0133, Edmonton, Alberta

Local Institution - 0001, Hamilton, Ontario

Local Institution - 0134, Montreal, Quebec

Local Institution - 0070, Odense, Syddanmark

Local Institution - 0047, Pessac, Aquitaine

Institut Paoli-Calmettes, Marseille, Bouches-du-Rhône

Hopital Claude Huriez - CHU de Lille, Lille, Nord

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Pays-de-la-Loire

Local Institution - 0046, Pierre-Bénite, Rhône

Henri Mondor Hospital, Créteil, Val-de-Marne

Local Institution - 0028, Villejuif, Val-de-Marne

Local Institution - 0029, Poitiers, Vienne

Local Institution - 0082, Paris, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Local Institution - 0031, Paris, Île-de-France

Local Institution - 0072, Heidelberg, Baden-Württemberg

Local Institution - 0078, Ulm, Baden-Württemberg

Local Institution - 0077, Nuremberg, Bayern

Local Institution - 0073, Köln, Nordrhein-Westfalen

Local Institution - 0087, Leipzig, Sachsen

Local Institution - 0079, Dresden, Not set

Local Institution - 0115, Essen, Not set

Local Institution - 0076, Hamburg, Not set

Local Institution - 0074, Wuerzburg, Not set

Local Institution - 0063, Patras, Achaḯa

Local Institution - 0061, Athens, Attikí

Local Institution - 0062, Chaidari, Attikí

Local Institution - 0060, Thessaloniki, Thessaloníki

Local Institution - 0055, Be'er Sheva, HaDarom

Local Institution - 0058, Petah-Tikva, HaMerkaz

Local Institution - 0057, Ramat Gan, HaMerkaz

Local Institution - 0088, Tel Aviv, Tell Abīb

Local Institution - 0056, Haifa, Not set

Local Institution - 0059, Jerusalem, Not set

Local Institution - 0064, Rozzano, Milano

Local Institution - 0065, Bologna, Not set

Local Institution - 0066, Roma, Not set

Nagoya City University Hospital, Nagoya, Aichi

Hokkaido University Hospital, Sapporo, Hokkaido

Hyogo Medical University Hospital, Nishinomiya, Hyogo

Kanazawa University Hospital, Kanazawa, Ishikawa

Local Institution - 0085, Isehara, Kanagawa

Japanese Red Cross Medical Center, Shibuya-ku, Tokyo

Chiba University Hospital, Chiba, Not set

Kyushu University Hospital, Fukuoka, Not set

Okayama University Hospital, Okayama, Not set

Local Institution - 0071, Shimotsuke, Not set

Chonnam National University Hwasun Hospital, Hwasun, Jeonranamdo

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Local Institution - 0038, Seoul, Seoul Teugbyeolsi

Local Institution - 0043, Seoul, Seoul Teugbyeolsi

Asan Medical Center, Seoul, Seoul-teukbyeolsi

Local Institution - 0069, Oslo, Not set

Local Institution - 0027, Lublin, Lubelskie

Local Institution - 0095, Warsaw, Mazowieckie

Local Institution - 0023, Warsaw, Mazowieckie

Local Institution - 0026, Gdańsk, Not set

Local Institution - 0024, Poznań, Not set

Local Institution - 0022, Gliwice, Śląskie

Local Institution - 0091, Bucharest, Not set

Local Institution - 0020, Badalona, Barcelona [Barcelona]

Local Institution - 0017, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Local Institution - 0012, Pamplona, Navarra

Local Institution - 0021, Madrid, Not set

Local Institution - 0013, Salamanca, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Local Institution - 0093, Birmingham, England

Local Institution - 0080, London, London, City Of

Local Institution - 0094, London, London, City Of

Conditions: Multiple Myeloma

Learn More ›

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

NCT01190930

Active Not Recruiting

This partially randomized phase III trial studies the side effects of different combinations of risk-adapted chemotherapy regimens and how well they work in treating younger patients with newly diagnosed standard-risk acute lymphoblastic leukemia or B-lineage lymphoblastic lymphoma that is found only in the tissue or organ where it began (localized). Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing,... Read More

Gender:

ALL

Ages:

Between 1 year and 30 years

Trial Updated:

03/13/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +242 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Providence Alaska Medical Center, Anchorage, Alaska

Banner Children's at Desert, Mesa, Arizona

Phoenix Childrens Hospital, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Mattel Children's Hospital UCLA, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

Naval Medical Center -San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Santa Barbara Cottage Hospital, Santa Barbara, California

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Lee Memorial Health System, Fort Myers, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

Miami Cancer Institute, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Tripler Army Medical Center, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Tulane University School of Medicine, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Nevada Cancer Research Foundation NCORP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Brooklyn Hospital Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

NYP/Weill Cornell Medical Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Brooke Army Medical Center, Fort Sam Houston, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Vannie Cook Children's Clinic, McAllen, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

John Hunter Children's Hospital, Hunter Regional Mail Centre, New South Wales

Sydney Children's Hospital, Randwick, New South Wales

Royal Brisbane and Women's Hospital, Herston, Queensland

Royal Children's Hospital-Brisbane, Herston, Queensland

Queensland Children's Hospital, South Brisbane, Queensland

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Monash Medical Center-Clayton Campus, Clayton, Victoria

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Our Lady's Children's Hospital, Dublin, Co Dublin

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

San Jorge Children's Hospital, San Juan, Not set

University Pediatric Hospital, San Juan, Not set

Swiss Pediatric Oncology Group - Geneva, Geneva, Not set

Swiss Pediatric Oncology Group - Lausanne, Lausanne, Not set

Conditions: Acute Lymphoblastic Leukemia, Adult B Lymphoblastic Lymphoma, Ann Arbor Stage I B Lymphoblastic Lymphoma, Ann Arbor Stage II B Lymphoblastic Lymphoma, Childhood B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Childhood B Lymphoblastic Lymphoma, Down Syndrome, Hypodiploid B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive

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Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis

NCT02222155

Completed

The aim of this trial is to test the safety and efficacy of two dose regimens of the complement C5a receptor CCX168 in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Funding Source - FDA OOPD

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/04/2025

Locations: Not set, Huntsville, Alabama +42 locations

Not set, Huntsville, Alabama

Not set, Phoenix, Arizona

Not set, Tucson, Arizona

Not set, Long Beach, California

Not set, Los Angeles, California

Not set, San Francisco, California

Not set, Aurora, Colorado

Not set, Washington, District of Columbia

Not set, Miami Springs, Florida

Not set, Tampa, Florida

Not set, Chicago, Illinois

Not set, Kansas City, Kansas

Not set, Lexington, Kentucky

Not set, Louisville, Kentucky

Not set, Shreveport, Louisiana

Not set, Charlestown, Massachusetts

Not set, Duluth, Minnesota

Not set, Tupelo, Mississippi

Not set, Saint Louis, Missouri

Not set, Reno, Nevada

Not set, Lebanon, New Hampshire

Not set, Albuquerque, New Mexico

Not set, Great Neck, New York

Not set, Mineola, New York

Not set, New York, New York

Not set, Syracuse, New York

Not set, Chapel Hill, North Carolina

Not set, New Bern, North Carolina

Not set, Columbus, Ohio

Not set, Duncansville, Pennsylvania

Not set, Philadelphia, Pennsylvania

Not set, Providence, Rhode Island

Not set, Charleston, South Carolina

Not set, Chattanooga, Tennessee

Not set, Amarillo, Texas

Not set, Austin, Texas

Not set, Houston, Texas

Not set, Salt Lake City, Utah

Not set, Seattle, Washington

Not set, Calgary, Alberta

Not set, Toronto, Ontario

Not set, Greenfield Park, Quebec

Not set, Levis, Quebec

Conditions: ANCA-associated Vasculitis

Learn More ›

A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis

NCT02994927

Completed

The primary objective is to evaluate the efficacy of CCX168 (avacopan) to induce and sustain remission in patients with active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), when used in combination with cyclophosphamide followed by azathioprine, or in combination with rituximab.

Gender:

ALL

Ages:

12 years and above

Trial Updated:

03/04/2025

Locations: Clinical Trial Site, Huntsville, Alabama +197 locations

Clinical Trial Site, Huntsville, Alabama

Clinical Trial Site, Phoenix, Arizona

Clinical Trial Site, Los Angeles, California

Clinical Trial Site, Santa Monica, California

Clinical Trial Site, Aurora, Colorado

Clinical Trial Site, Washington, District of Columbia

Clinical Trial Site, Daytona Beach, Florida

Clinical Trial Site, Tampa, Florida

Clinical Trial Site, Atlanta, Georgia

Clinical Trial Site, Meridian, Idaho

Clinical Trial Site, Chicago, Illinois

Clinical Trial Site, Indianapolis, Indiana

Clinical Trial Site, Kansas City, Kansas

Clinical Trial Site, Lexington, Kentucky

Clinical Trial Site, Shreveport, Louisiana

Clinical Trial Site, Baltimore, Maryland

Clinical Trial Site, Boston, Massachusetts

Clinical Trial Site, Ann Arbor, Michigan

Clinical Trial Site, Minneapolis, Minnesota

Clinical Trial Site, Rochester, Minnesota

Clinical Trial Site, Saint Louis, Missouri

Clinical Trial Site, Great Neck, New York

Clinical Trial Site, Mineola, New York

Clinical Trial Site, New York, New York

Clinical Trial Site, Chapel Hill, North Carolina

Clinical Trial Site, Greenville, North Carolina

Clinical Trial Site, Winston-Salem, North Carolina

Clinical Trial Site, Cleveland, Ohio

Clinical Trial Site, Columbus, Ohio

Clinical Trial Site, Duncansville, Pennsylvania

Clinical Trial Site, Philadelphia, Pennsylvania

Clinical Trial Site, Pittsburgh, Pennsylvania

Clinical Trial Site, Providence, Rhode Island

Clinical Trial Site, Charleston, South Carolina

Clinical Trial Site, Dallas, Texas

Clinical Trial Site, Houston, Texas

Clinical Trial Site, Salt Lake City, Utah

Clinical Trial Site, Seattle, Washington

Clinical Trial Site, Adelaide, Not set

Clinical Trial Site, Auchenflower, Not set

Clinical Trial Site, Brisbane, Not set

Clinical Trial Site, Clayton, Not set

Clinical Trial Site, Concord, Not set

Clinical Trial Site, Heidelberg, Not set

Clinical Trial Site, Liverpool, Not set

Clinical Trial Site, Nambour, Not set

Clinical Trial Site, Nedlands, Not set

Clinical Trial Site, Randwick, Not set

Clinical Trial Site, Saint Albans, Not set

Clinical Trial Site, Southport, Not set

Clinical Trial Site, St Leonards, Not set

Clinical Trial Site, Westmead, Not set

Clinical Trial Site, Woolloongabba, Not set

Clinical Trial Site, Feldkirch, Not set

Clinical Trial Site, Graz, Not set

Clinical Trial Site, Innsbruck, Not set

Clinical Trial Site, Antwerp, Not set

Clinical Trial Site, Brussels, Not set

Clinical Trial Site, Leuven, Not set

Clinical Trial Site, Liège, Not set

Clinical Trial Site, Calgary, Not set

Clinical Trial Site, Greenfield Park, Not set

Clinical Trial Site, Hamilton, Not set

Clinical Trial Site, Montréal, Not set

Clinical Trial Site, Québec, Not set

Clinical Trial Site, Sherbrooke, Not set

Clinical Trial Site, Toronto, Not set

Clinical Trial Site, Vancouver, Not set

Clinical Trial Site, Olomouc, Not set

Clinical Trial Site, Praha, Not set

Clinical Trial Site, Aalborg, Not set

Clinical Trial Site, Aarhus, Not set

Clinical Trial Site, Copenhagen, Not set

Clinical Trial Site, Odense, Not set

Clinical Trial Site, Roskilde, Not set

Clinical Trial Site, Angers, Not set

Clinical Trial Site, Bordeaux, Not set

Clinical Trial Site, Boulogne-sur-Mer, Not set

Clinical Trial Site, Brest, Not set

Clinical Trial Site, Bron, Not set

Clinical Trial Site, Caen, Not set

Clinical Trial Site, Colmar, Not set

Clinical Trial Site, Grenoble, Not set

Clinical Trial Site, Marseille, Not set

Clinical Trial Site, Metz, Not set

Clinical Trial Site, Nantes, Not set

Clinical Trial Site, Nîmes, Not set

Clinical Trial Site, Paris, Not set

Clinical Trial Site, Toulouse, Not set

Clinical Trial Site, Valenciennes, Not set

Clinical Trial Site, Aachen, Not set

Clinical Trial Site, Bad Bramstedt, Not set

Clinical Trial Site, Berlin, Not set

Clinical Trial Site, Cologne, Not set

Clinical Trial Site, Dresden, Not set

Clinical Trial Site, Essen, Not set

Clinical Trial Site, Freiburg, Not set

Clinical Trial Site, Fulda, Not set

Clinical Trial Site, Hamburg, Not set

Clinical Trial Site, Hannover, Not set

Clinical Trial Site, Heidelberg, Not set

Clinical Trial Site, Jena, Not set

Clinical Trial Site, Kirchheim unter Teck, Not set

Clinical Trial Site, Leipzig, Not set

Clinical Trial Site, Ludwigshafen, Not set

Clinical Trial Site, Lübeck, Not set

Clinical Trial Site, Mannheim, Not set

Clinical Trial Site, Munich, Not set

Clinical Trial Site, Tuebingen, Not set

Clinical Trial Site, Villingen-Schwenningen, Not set

Clinical Trial Site, Budapest, Not set

Clinical Trial Site, Debrecen, Not set

Clinical Trial Site, Cork, Not set

Clinical Trial Site, Dublin, Not set

Clinical Trial Site, Ancona, Not set

Clinical Trial Site, Firenze, Not set

Clinical Trial Site, Genova, Not set

Clinical Trial Site, Milano, Not set

Clinical Trial Site, Monza, Not set

Clinical Trial Site, Parma, Not set

Clinical Trial Site, Reggio Emilia, Not set

Clinical Trial Site, Torino, Not set

Clinical Trial Site, Udine, Not set

Clinical Trial Site, Aichi, Not set

Clinical Trial Site, Akita, Not set

Clinical Trial Site, Chiba, Not set

Clinical Trial Site, Hiroshima, Not set

Clinical Trial Site, Hokkaido, Not set

Clinical Trial Site, Ishikawa, Not set

Clinical Trial Site, Kagawa, Not set

Clinical Trial Site, Kanagawa, Not set

Clinical Trial Site, Kobe, Not set

Clinical Trial Site, Miyazaki, Not set

Clinical Trial Site, Nagoya, Not set

Clinical Trial Site, Okayama, Not set

Clinical Trial Site, Osaka, Not set

Clinical Trial Site, Saitama, Not set

Clinical Trial Site, Shimane, Not set

Clinical Trial Site, Shizuoka, Not set

Clinical Trial Site, Tokyo, Not set

Clinical Trial Site, Toyama, Not set

Clinical Trial Site, Yokohama, Not set

Clinical Trial Site, Groningen, Not set

Clinical Trial Site, Leiden, Not set

Clinical Trial Site, Rotterdam, Not set

Clinical Trial Site, Christchurch, Not set

Clinical Trial Site, Dunedin, Not set

Clinical Trial Site, Grafton, Not set

Clinical Trial Site, Hamilton, Not set

Clinical Trial Site, Takapuna, Not set

Clinical Trial Site, Nordbyhagen, Not set

Clinical Trial Site, Oslo, Not set

Clinical Trial Site, Tromsø, Not set

Clinical Trial Site, Badalona, Not set

Clinical Trial Site, Barcelona, Not set

Clinical Trial Site, Burela, Not set

Clinical Trial Site, Lleida, Not set

Clinical Trial Site, Madrid, Not set

Clinical Trial Site, San Sebastián, Not set

Clinical Trial Site, Linköping, Not set

Clinical Trial Site, Lund, Not set

Clinical Trial Site, Stockholm, Not set

Clinical Trial Site, Uppsala, Not set

Clinical Trial Site, Örebro, Not set

Clinical Trial Site, Basel, Not set

Clinical Trial Site, Bern, Not set

Clinical Trial Site, Fribourg, Not set

Clinical Trial Site, Lausanne, Not set

Clinical Trial Site, St. Gallen, Not set

Clinical Trial Site, Zürich, Not set

Clinical Trial Site, Aberdeen, Not set

Clinical Trial Site, Basildon, Not set

Clinical Trial Site, Birmingham, Not set

Clinical Trial Site, Bristol, Not set

Clinical Trial Site, Cambridge, Not set

Clinical Trial Site, Canterbury, Not set

Clinical Trial Site, Cardiff, Not set

Clinical Trial Site, Carshalton, Not set

Clinical Trial Site, Dorchester, Not set

Clinical Trial Site, Dudley, Not set

Clinical Trial Site, Exeter, Not set

Clinical Trial Site, Glasgow, Not set

Clinical Trial Site, Inverness, Not set

Clinical Trial Site, Kirkcaldy, Not set

Clinical Trial Site, Leeds, Not set

Clinical Trial Site, Leicester, Not set

Clinical Trial Site, Liverpool, Not set

Clinical Trial Site, London, Not set

Clinical Trial Site, Manchester, Not set

Clinical Trial Site, Newcastle, Not set

Clinical Trial Site, Nottingham, Not set

Clinical Trial Site, Oxford, Not set

Clinical Trial Site, Reading, Not set

Clinical Trial Site, Salford, Not set

Clinical Trial Site, Westcliff-on-Sea, Not set

Conditions: ANCA-Associated Vasculitis

Learn More ›

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

NCT02828358

Completed

This pilot phase II trial studies the side effects of azacitidine and combination chemotherapy in infants with acute lymphoblastic leukemia and KMT2A gene rearrangement. Drugs used in chemotherapy, such as methotrexate, prednisolone, daunorubicin hydrochloride, cytarabine, dexamethasone, vincristine sulfate, pegaspargase, hydrocortisone sodium succinate, azacitidine, cyclophosphamide, mercaptopurine, leucovorin calcium, and thioguanine work in different ways to stop the growth of cancer cells, e... Read More

Gender:

ALL

Ages:

364 days and below

Trial Updated:

02/26/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +169 locations

Children's Hospital of Alabama, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Providence Alaska Medical Center, Anchorage, Alaska

Banner Children's at Desert, Mesa, Arizona

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

UCSF Medical Center-Mission Bay, San Francisco, California

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Albany Medical Center, Albany, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

West Virginia University Charleston Division, Charleston, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Princess Margaret Hospital for Children, Perth, Western Australia

Perth Children's Hospital, Perth, Western Australia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

HIMA San Pablo Oncologic Hospital, Caguas, Not set

San Jorge Children's Hospital, San Juan, Not set

University Pediatric Hospital, San Juan, Not set

Conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia

Learn More ›

N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan

NCT02030964

Completed

This study will combine an oral drug called DFMO with celecoxib (also oral) and two IV chemotherapy medicines called cyclophosphamide and topotecan. * To find the highest dose of DFMO that can be given with celecoxib, cyclophosphamide and topotecan without causing severe side effects. * To find out the side effects seen by giving DFMO at different dose levels with celecoxib, cyclophosphamide and topotecan. * To measure the levels of DFMO in the blood at different dose levels. * To determine if... Read More

Gender:

ALL

Ages:

Between 2 years and 30 years

Trial Updated:

02/13/2025

Locations: Children's Hospital Los Angeles, Los Angeles, California +12 locations

Conditions: Neuroblastoma

Learn More ›

Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma

NCT02298348

Active Not Recruiting

This study will combine three drugs: sorafenib, cyclophosphamide and topotecan. Adding sorafenib to cyclophosphamide and topotecan may increase the effectiveness of this combination. The investigators first need to find out the highest dose of sorafenib that can be given safely together with cyclophosphamide and topotecan. This is the first study to test giving these three drugs together and will help determine the highest dose of sorafenib that can safely be given together with cyclophosphamid... Read More

Gender:

ALL

Ages:

30 years and below

Trial Updated:

02/13/2025

Locations: Children's Hospital Los Angeles, Los Angeles, California +11 locations

Conditions: Neuroblastoma

Learn More ›

Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma

NCT02625480

Active Not Recruiting

The primary objectives of this study are to evaluate the safety and efficacy of brexucabtagene autoleucel (KTE-X19) in pediatric and adolescent participants with relapsed/refractory (r/r) B-precursor acute lymphoblastic leukemia (ALL) or relapsed or refractory (r/r) B-cell non-Hodgkin lymphoma (NHL). As of October 2022, no further patients with acute B-cell Acute Lymphoblastic Leukemia (ALL) will be asked to join the study. The study remains open for recruitment for patients that have B-cell No... Read More

Gender:

ALL

Ages:

21 years and below

Trial Updated:

02/13/2025

Locations: Children's Hospital Los Angeles, Los Angeles, California +29 locations

Children's Hospital Los Angeles, Los Angeles, California

Children's Hospital of Orange County, Orange, California

UCSF Benioff Children's Hospital, San Francisco, California

University of Miami Hospital & Clinics, Miami, Florida

Kapi'olani Medical Center for Women and Children, Honolulu, Hawaii

Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois

Johns Hopkins University, Baltimore, Maryland

Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota

Columbia University Irving Medical Center/Morgan Stanley Children's Hospital-NYP, New York, New York

University of Rochester Medical Center, Rochester, New York

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Monroe-Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee

Texas Children's Hospital, Houston, Texas

The University of Texas M.D. Anderson Cancer Center, Houston, Texas

University of Virginia Health System, Pediatric Hematology/Oncology Clinic, Charlottesville, Virginia

University Hospital Gent, Gent, Not set

The Hospital for Sick Children, Toronto, Not set

University Hospital Brno, Brno, Not set

Unité d'Oncologie et Hématologie Pédiatriques, Bordeaux, Not set

Institut d'Hematologie et Oncologie Pediatrique, Lyon, Not set

Hopital d'Enfants la Timone, Marseille Cedex 5, Not set

Hopital Robert Debre - Sevice d'Hemato-immunologic, Paris Cedex 19, Not set

University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Not set

Bambino Gesù Children's Hospital, Rome, Not set

Prinses Maxima Centrum, Utrecht, Not set

Jurasz University Hospital 1; Collegium Medicum, Bydgoszcz, Not set

Wroclaw Medical University, Wroclaw, Not set

Hospital Sant Joan de Déu, Barcelona, Not set

Hospital Universitario La Paz, Madrid, Not set

Karolinska University Hospital, Stockholm, Not set

Conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia, Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma

Learn More ›

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

NCT03113500

Active Not Recruiting

This phase II trial studies the side effects and how well brentuximab vedotin and combination chemotherapy work in treating patients with CD30-positive peripheral T-cell lymphoma. Brentuximab vedotin is a monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in a targeted way and delivers vedotin to kill them. Drugs used in chemotherapy, such as cyclophosphamide, doxorubicin, etoposide, and prednisone work in different ways t... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

02/04/2025

Locations: City of Hope Comprehensive Cancer Center, Duarte, California +4 locations

Conditions: Adult T-Cell Leukemia/Lymphoma, Anaplastic Large Cell Lymphoma, ALK-Negative, Anaplastic Large Cell Lymphoma, ALK-Positive, Angioimmunoblastic T-Cell Lymphoma, Ann Arbor Stage II Noncutaneous Anaplastic Large Cell Lymphoma, Ann Arbor Stage III Noncutaneous Anaplastic Large Cell Lymphoma, Ann Arbor Stage IV Noncutaneous Anaplastic Large Cell Lymphoma, Enteropathy-Associated T-Cell Lymphoma, Hepatosplenic T-Cell Lymphoma, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified

Learn More ›

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

NCT00408005

Active Not Recruiting

This randomized phase III trial is studying different combination chemotherapy regimens and their side effects and comparing how well they work in treating young patients with newly diagnosed T-cell acute lymphoblastic leukemia or T-cell lymphoblastic lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is no... Read More

Gender:

ALL

Ages:

Between 1 year and 30 years

Trial Updated:

02/01/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +214 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Lee Memorial Health System, Fort Myers, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

Miami Cancer Institute, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Tripler Army Medical Center, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kansas Cancer Center, Kansas City, Kansas

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Tulane University School of Medicine, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Nevada Cancer Research Foundation NCORP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Brooklyn Hospital Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Weill Cornell Medical Center, New York, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Royal Brisbane and Women's Hospital, Herston, Queensland

Royal Children's Hospital-Brisbane, Herston, Queensland

Queensland Children's Hospital, South Brisbane, Queensland

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Monash Medical Center-Clayton Campus, Clayton, Victoria

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

Swiss Pediatric Oncology Group - Geneva, Geneva, Not set

Swiss Pediatric Oncology Group - Lausanne, Lausanne, Not set

Conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma

Learn More ›

A Study of the Bruton's Tyrosine Kinase Inhibitor, PCI-32765 (Ibrutinib), in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma

NCT01855750

Completed

The purpose of this study is to evaluate if ibrutinib administered in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) improves the clinical outcome in newly diagnosed patients with non-germinal center B-cell subtype (GCB) of diffuse large B-cell lymphoma (DLBCL) selected by immunohistochemistry (IHC) or newly diagnosed patients with activated B cell-like (ABC) subtype of DLBCL identified by gene expression profiling (GEP) or both populations.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/31/2025

Locations: Not set, Tucson, Arizona +204 locations

Not set, Tucson, Arizona

Not set, Greenbrae, California

Not set, La Jolla, California

Not set, Los Angeles, California

Not set, Salinas, California

Not set, Stanford, California

Not set, Danbury, Connecticut

Not set, Hartford, Connecticut

Not set, Washington, District of Columbia

Not set, Atlanta, Georgia

Not set, Marietta, Georgia

Not set, Peoria, Illinois

Not set, Fort Wayne, Indiana

Not set, Goshen, Indiana

Not set, Indianapolis, Indiana

Not set, Topeka, Kansas

Not set, Louisville, Kentucky

Not set, Baton Rouge, Louisiana

Not set, New Orleans, Louisiana

Not set, Baltimore, Maryland

Not set, Bethesda, Maryland

Not set, Boston, Massachusetts

Not set, Ann Arbor, Michigan

Not set, Saint Louis, Missouri

Not set, Omaha, Nebraska

Not set, Hackensack, New Jersey

Not set, New Brunswick, New Jersey

Not set, Bronx, New York

Not set, Fresh Meadows, New York

Not set, Johnson City, New York

Not set, Mineola, New York

Not set, New York, New York

Not set, Rochester, New York

Not set, Charlotte, North Carolina

Not set, Greenville, North Carolina

Not set, Hickory, North Carolina

Not set, Columbus, Ohio

Not set, Portland, Oregon

Not set, North Charleston, South Carolina

Not set, Nashville, Tennessee

Not set, Houston, Texas

Not set, Temple, Texas

Not set, Burlington, Vermont

Not set, Seattle, Washington

Not set, Buenos Aires, Not set

Not set, Ciudad Autonoma de Buenos Aires, Not set

Not set, Ciudad de Buenos Aires, Not set

Not set, Adelaide, Not set

Not set, Concord, Not set

Not set, Darlinghurst, Not set

Not set, Hobart, Not set

Not set, Melbourne, Not set

Not set, Nedlands, Not set

Not set, Perth, Not set

Not set, Randwick, Not set

Not set, South Brisbane, Not set

Not set, Woolloongabba, Not set

Not set, Antwerpen, Not set

Not set, Brugge, Not set

Not set, Brussel, Not set

Not set, Gent, Not set

Not set, Haine Saint Paul La Louviere, Not set

Not set, Kortrijk, Not set

Not set, Leuven, Not set

Not set, Porto Alegre, Not set

Not set, Rio De Janeiro, Not set

Not set, Sao Paulo, Not set

Not set, Edmonton, Alberta

Not set, Vancouver, British Columbia

Not set, Halifax, Nova Scotia

Not set, Toronto, Ontario

Not set, Levis, Quebec

Not set, Montreal, Quebec

Not set, Montréal, Quebec

Not set, Beijing, Not set

Not set, Changchun, Not set

Not set, Chengdu, Not set

Not set, Guangzhou, Not set

Not set, Hangzhou, Not set

Not set, Harbin, Not set

Not set, Jinan, Not set

Not set, Nanjing, Not set

Not set, Shanghai, Not set

Not set, Tianjin, Not set

Not set, Brno, Not set

Not set, Hradec Kralove, Not set

Not set, Ostrava, Not set

Not set, Praha 10, Not set

Not set, Praha 2, Not set

Not set, Aarhus N., Not set

Not set, Copenhagen, Not set

Not set, Roskilde, Not set

Not set, Vejle, Not set

Not set, Helsinki, Not set

Not set, Jyväskylä, Not set

Not set, Oulu, Not set

Not set, Turku, Not set

Not set, Grenoble Cedex 9, Not set

Not set, Limoges, Not set

Not set, Paris, Not set

Not set, Pessac, Not set

Not set, Pierre Benite, Not set

Not set, Rouen, Not set

Not set, Tours, Not set

Not set, Villejuif, Not set

Not set, Augsburg, Not set

Not set, Bamberg, Not set

Not set, Berlin, Not set

Not set, Dresden, Not set

Not set, Essen, Not set

Not set, Frankfurt, Not set

Not set, Jena, Not set

Not set, Muenchen, Not set

Not set, Münster, Not set

Not set, Villingen-Schwenningen, Not set

Not set, Budapest N/a, Not set

Not set, Debrecen, Not set

Not set, Gyula, Not set

Not set, Szombathely, Not set

Not set, Veszprém, Not set

Not set, Beer-Sheva, Not set

Not set, Hadera, Not set

Not set, Haifa, Not set

Not set, Petah Tikva, Not set

Not set, Ramat-Gan, Not set

Not set, Tel Aviv, Not set

Not set, Fukuoka, Not set

Not set, Hiroshima, Not set

Not set, Isehara, Not set

Not set, Kobe, Not set

Not set, Kumamoto, Not set

Not set, Kyoto, Not set

Not set, Nagano, Not set

Not set, Nagoya, Not set

Not set, Narita, Not set

Not set, Osaka-Sayama, Not set

Not set, Osaka, Not set

Not set, Sapporo, Not set

Not set, Sendai-shi, Not set

Not set, Suita, Not set

Not set, Tachikawa, Not set

Not set, Tokyo, Not set

Not set, Tsukuba, Not set

Not set, Busan, Not set

Not set, Goyang-Si, Not set

Not set, Seoul, Not set

Not set, Mexico, Not set

Not set, Monterrey, Not set

Not set, San Luis Potosi, Not set

Not set, Amsterdam Zuidoost, Not set

Not set, Arnhem, Not set

Not set, Dordrecht, Not set

Not set, Groningen, Not set

Not set, Leiden, Not set

Not set, Nieuwegein, Not set

Not set, Rotterdam, Not set

Not set, Oslo, Not set

Not set, Tromso, Not set

Not set, Brzozow, Not set

Not set, Chorzow, Not set

Not set, Krakow, Not set

Not set, Lodz, Not set

Not set, Olsztyn, Not set

Not set, Poznan, Not set

Not set, Warszawa, Not set

Not set, Wroclaw, Not set

Not set, Ekaterinburg, Not set

Not set, Moscow, Not set

Not set, Nizhny Novgorod, Not set

Not set, Rostov-Na-Donu, Not set

Not set, Saint-Petersburg, Not set

Not set, Sochi, Not set

Not set, St. Petersburg, Not set

Not set, Volgograd, Not set

Not set, Barcelona, Not set

Not set, Madrid, Not set

Not set, Salamanca, Not set

Not set, Sevilla, Not set

Not set, Linköping, Not set

Not set, Luleå, Not set

Not set, Lund, Not set

Not set, Uppsala, Not set

Not set, Taichung, Not set

Not set, Tainan, Not set

Not set, Taoyuan County, Not set

Not set, Adana, Not set

Not set, Ankara, Not set

Not set, Istanbul, Not set

Not set, Izmir, Not set

Not set, Kayseri, Not set

Not set, Samsun, Not set

Not set, Cherkassy, Not set

Not set, Khmelnitskiy, Not set

Not set, Kiev, Not set

Not set, Lviv, Not set

Not set, Makiivka, Not set

Not set, Glasgow, Not set

Not set, Liverpool, Not set

Not set, London, Not set

Not set, Maidstone, Not set

Not set, Manchester, Not set

Not set, Nottingham, Not set

Not set, Oxford, Not set

Not set, Romford, Not set

Not set, Southampton, Not set

Conditions: Lymphoma

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Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta

NCT05950802

Recruiting

This is a Phase 1b study of participants with Diffuse Large B Cell Lymphoma (DLBCL). The purpose of this study is to identify an optimized lymphodenpletion (LD) regimen by evaluating standard and intermediate doses of Fludarabine (Flu) / Cyclophosphamide (Cy) with or without a fixed dose of total lymphoid irradiation (TLI) in the setting of standard of care CAR T cell therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/30/2025

Locations: Princess Margaret Cancer Centre, Toronto, Ontario

Conditions: DLBCL - Diffuse Large B Cell Lymphoma

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