There are currently 86 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Atrial Fibrillation participants are Florida, California, Ontario and Texas.
Amplatzer Amulet LAAO vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +126 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Data-driven SDM to Reduce Symptom Burden in AF
NCT04993807
Recruiting
This study is a single-group feasibility study evaluating decision aid visualizations which display common post-ablation symptom patterns as a tool for shared decision-making. The specific aim of the clinical trial is to evaluate the feasibility of putting the visualizations into clinical practice (n=75). The hypothesis is that patients will report low decisional conflict and decision regret and high satisfaction with their decision about whether to undergo an ablation or not.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Weill Cornell Medicine, New York, New York +1 locations
Conditions: Atrial Fibrillation, Patient Engagement
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Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
NCT06063538
Recruiting
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG) or valve surgery.
Gender:
All
Ages:
Between 20 years and 85 years
Trial Updated:
04/15/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Atrial Fibrillation, Post-Op Complication
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The Z Stitch Early Bed Rest Assessment Study
NCT06087497
Recruiting
The goal of this study is to understand the effects of early mobilization after a Z stitch procedure in patients undergoing certain heart-related treatments. The investigators want to find out if allowing patients to move around sooner after their procedure can improve their satisfaction and potentially lead to earlier discharge from the hospital. Type of Study: Clinical Trial Participant Population/Health Conditions: Patients aged 18-99 undergoing specific heart procedures such as atrial fibr... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/11/2024
Locations: Oregon Health and Science University, Portland, Oregon +1 locations
Conditions: Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia, Syncope, Ventricular Tachycardia
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Using Electrical Nerve Stimulation to Control Atrial Fibrillation
NCT04529941
Recruiting
The purpose of this study is to examine if sending mild electrical signals just under your skin will improve atrial fibrillation symptoms by controlling your heart rate.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/01/2024
Locations: CedarsSinaiMC, Los Angeles, California
Conditions: Atrial Fibrillation
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Dynamic Data-Driven Management of Atrial Fibrillation Using Implantable Cardiac Monitors: The MONITOR-AF Study
NCT06352060
Recruiting
Observational, multi-center, retrospective study to evaluate the use of ICM (implantable cardiac monitor) versus traditional, non-ICM (non-implantable cardiac monitor) methods such as ECGs (electrocardiogram), Holter, and mobile cardiac outpatient telemetry (MCOT) units.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: Menorah Medical Center, Overland Park, Kansas +6 locations
Conditions: Atrial Fibrillation
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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
NCT03907046
Recruiting
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes as measured by the modified Rankin Scale.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: University of Alabama Hospital, Birmingham, Alabama +155 locations
Conditions: Intracerebral Hemorrhage, Atrial Fibrillation
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Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF
NCT02456233
Recruiting
This prospective randomized study will assess the safety and efficacy of FIRM-guided ablation (FIRM+PVI) compared to pulmonary vein isolation (PVI) without FIRM, for the treatment of symptomatic atrial fibrillation.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/12/2024
Locations: Veterans Affairs Medical Center, San Diego, California +1 locations
Conditions: Atrial Fibrillation
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Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients
NCT04818645
Recruiting
Patients with heart failure (HF) represent a large population of patients who are at high risk for complications related to undiagnosed atrial fibrillation (AF). However, currently there are limited modalities for early AF detection and subsequent stroke prevention in this high-risk population. An implantable cardiac monitor (ICM) is inserted subcutaneously and can provide long term arrhythmia information via remote monitoring. The ASSERT-AF study seeks to accurately define the burden of AF and... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Atrial Fibrillation, Heart Failure
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Synaptic Plasticity in the Epicardial Ganglionated Plexi
NCT05034419
Recruiting
Atrial fibrillation (AF) is the most common arrhythmia and the prevalence increase with age. Autonomic nervous system play a critical role in the initiation and maintenance of AF. The intrinsic cardiac autonomic nervous system includes ganglionated plexus (GP) modulate the level of parasympathetic activity to the heart. Experimental and clinical studies suggest that GP activation plays a significant role in clinical AF in both the initiation of and the maintenance of AF. Synaptic plasticity is... Read More
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
03/04/2024
Locations: OU Medical Center, Oklahoma City, Oklahoma
Conditions: Atrial Fibrillation
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Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation
NCT05190679
Recruiting
This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation. The study will enroll 225 participants. Eligible participants will have undergone sequencing for arrhythmia and cardiomyopathy (CM) genes. Based on those results, participants will be recruited for an outpatient research visit with testing that includes cardiac MRI, rest/stre... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/02/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Atrial Fibrillation
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The Vanderbilt Atrial Fibrillation Ablation Registry
NCT02404415
Recruiting
The Vanderbilt Atrial Fibrillation Ablation registry (VAFAR) is a prospective clinical and genetic biorepository that systematically enrolls patients undergoing atrial fibrillation (AF) ablation. The registry was started in 2011 and has greater than 1000 AF ablation records with stored blood and DNA samples. The goals of VAFAR are to: 1) identify clinical, genetic, and serological predictors of response to AF ablation in order to improve patient selection, and 2) to provide a resource for transl... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/02/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Atrial Fibrillation
Register for Updates