There are currently 86 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Atrial Fibrillation participants are Florida, California, Ontario and Texas.
The Fourth Left Atrial Appendage Occlusion Study
NCT05963698
Recruiting
LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite receiving ongoing treatment with oral anticoagulation.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Arrhythmia Research Group, Jonesboro, Arkansas +1 locations
Conditions: Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
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Positron Emission Tomography (PET) Imaging of Thrombosis
NCT03830320
Recruiting
The purpose of the study is to evaluate a new radiotracer called 64Cu-FBP8 for PET-MR imaging of thrombosis. The tracer has the potential of detecting thrombosis anywhere in the body, for instance in the left atrial appendage of patients with atrial fibrillation, and thereby may provide a non-invasive alternative to the current standard-of-care methods.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/01/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Atrial Fibrillation, COVID-19, Cancer, Thrombosis
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Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
NCT02347111
Recruiting
In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will test the hypothesis that a common AF genetic risk allele modulates response to different AADs.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
11/28/2023
Locations: Jesse Brown VA Medical Center, Chicago, Illinois +3 locations
Conditions: Atrial Fibrillation
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COMParison of Algorithms for Rotational Evaluation in Atrial Fibrillation
NCT02997254
Recruiting
This is a cohort study to evaluate algorithms for mapping atrial fibrillation by mapping atrial structure and mapping electrical activity to detect focal and rotational activity.
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Abnormal Heart Rhythms
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The Dynamics of Human Atrial Fibrillation
NCT05366361
Recruiting
Atrial fibrillation (AF) is an enormous public health problem in the United States, affecting 2-5 million Americans and causing rapid heart beats, stroke, heart failure or death. In this project, the applicant will develop a novel framework to better understand human AF that builds on agreement between several concepts for the disease. The applicant will develop strategies to identify AF patients who will best respond to each of several therapies, to guide personalized therapy.
Gender:
All
Ages:
Between 22 years and 80 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
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Machine Learning in Atrial Fibrillation
NCT05371405
Recruiting
Atrial fibrillation is a serious public health issue that affects over 5 million Americans (Miyazaka, Circulation 2006) in whom it may cause skipped beats, dizziness, stroke and even death. Therapy for AF is currently suboptimal, in part because AF represents several disease states of which few have been delineated or used to successfully guide management. This study seeks to clarify this delineation of AF types using machine learning (ML).
Gender:
All
Ages:
Between 22 years and 80 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2023
Locations: CHI St. Vincent, Arkansas, Little Rock, Arkansas +89 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Peri-Atrial Inflammatory Fat and Atrial Fibrillation
NCT04186169
Recruiting
Atrial fibrillation (AF) impacts the lives of 30 million people worldwide. Pulmonary vein isolation (PVI) by catheter ablation is effective for paroxysmal AF, but the success rate remains marginal at 60-80%. For persistent AF, defined as continuous AF that sustains longer than 7 days, the success rate is even lower. The low success rate of AF ablation reflects the fact that there is no effective target identified to modify the underlying substrate beyond PVI. Recently, investigators have made an... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
11/08/2023
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Atrial Fibrillation
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Does Eliminating Coffee Avoid Fibrillation?
NCT05121519
Recruiting
Given both the increasing population impact of atrial fibrillation (AF) and the widespread consumption of coffee in society, determining an associated benefit or risk of coffee consumption on AF is of great clinical relevance. This pilot study will evaluate the effect of randomly assigning participants undergoing electrical cardioversion to coffee abstinence or coffee consumption over a 6 month period. This pilot study will provide the first, randomized evaluation of coffee on AF outcomes and wi... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
10/25/2023
Locations: UCSF Parnassus, San Francisco, California
Conditions: Atrial Fibrillation, Coffee
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Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation
NCT05504356
Recruiting
VIBRANT-AF seeks to: Identify clinically relevant predictors of effectiveness and complications of AF ablation procedures in a prospective, US-based, multi-center, real-world longitudinal study Assess changes in modifiable lifestyle-related exposures influence the effectiveness of AF ablation Determine incidence and predictors of complications of AF ablation procedures Participants will connect with the Eureka Research Platform and answer a series of surveys and activities over a one-year peri... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/24/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Atrial Fibrillation
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A Trial of Pharmacist Management of Oral Anticoagulation THerapy Versus Enhanced Usual CARe in the communitY for AF
NCT04907825
Recruiting
This is a prospective, open-label, cluster-randomized controlled trial of 400 participants (aged 60 years or older, with additional stroke risk factors and 'actionable' undertreated AF) from a total of 40 retail and outpatient community pharmacies. Participants will be randomized (by pharmacy) to either to an intervention arm of pharmacist-led OAC management versus an enhanced usual care arm, wherein physicians receive notification of 'actionable' AF and patients are advised to schedule a physic... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
10/20/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Atrial Fibrillation, Stroke
Register for Updates
Efficacy Rate of Unipolar Polarity Switch for Lesion Assessment in Pulmonary Vein Isolation
NCT05464537
Recruiting
The technique of intraprocedural electrogram morphology as a measure of lesion effectiveness in an attempt to achieve durable PVI, clearly led to shortened procedural time, radiation exposure, and superiority in outcomes, with the implementation of a reproducible, readily available intraprocedural tool that can be applied universally.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Kansas City Heart Rhythm Institute, Overland Park, Kansas +1 locations
Conditions: Atrial Fibrillation
Register for Updates