There are currently 84 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Autism participants are Florida, California, Ontario and Texas.
High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
Recruiting
Patients undergoing FIRM guided ablation of atrial fibrillation will undergo high resolution MRI imaging to determine correlation of underlying anatomic fibrotic regions with FIRM targeted sites for ablation.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Ohio State University, Columbus, Ohio
Conditions: Atrial Fibrillation
Biomarkers of Acute Stroke in Clinic
Recruiting
The proposed study will investigate the clinical use of the ISCDX test that may differentiate between diverse stroke etiologies as listed below: Aim 1: Differentiate between cardioembolic and large artery atherosclerotic ischemic strokes, when hemorrhagic stroke is ruled out, as defined by TOAST classification of subtypes of acute ischemic stroke. Aim 2: In cases of ischemic strokes of unknown or "cryptogenic" etiology, determine the ability of biomarker blood tests to predict etiology between... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/26/2023
Locations: Ohio Health Riveside Methodist Hospital, Columbus, Ohio
Conditions: Ischemic Stroke, Ischemia, Atrial Fibrillation, Transient Ischemic Attack, Transient Cerebrovascular Events, Thrombotic Stroke, Stroke, Stroke, Acute, Stroke, Ischemic, Stroke, Complication, Stroke of Basilar Artery, Atherosclerosis, Atheroma, Cardioembolic Stroke, Cardiomyopathies, Cardiovascular Stroke, Thromboembolism
Development of CIRC Technologies
Recruiting
Cardiovascular disease is the leading cause of death worldwide. Advanced cardiovascular imaging using Magnetic Resonance Imaging (MRI) has proven to be effective in providing gold standard myocardial tissue characterization. Moreover, the intrinsic advantage of MRI's lack of exposure to ionizing radiation is particularly beneficial. At the same time, blood work can be very useful in early detection of certain cardiomyopathy, such as amyloid. However, there is a lack of agreement of on which mark... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Cardiovascular Innovation Research Center, Cleveland, Ohio
Conditions: Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease, Non-ischemic Cardiomyopathy, Valvular Heart Disease, Metabolic Cardiomyopathy, Congenital Heart Disease, Aortic Diseases, Atrial Fibrillation, Ventricular Fibrillation
Intracardiac Echocardiography Guided Watchman Device Implant
Recruiting
This study is to look at the success of Intracardiac Echocardiography (ICE) in the Watchman procedure. Currently the process is to use a Transesophageal Echocardiography (TEE) to place the Watchman in patients. This study is aiming to show how the ICE is just as effective in placing the device correctly and effectively.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/29/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Atrial Fibrillation, Left Atrial Appendage Thrombosis
A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation
Recruiting
The purpose of this study is to evaluate if milvexian is at least as effective as apixaban for reducing the risk of the composite stroke and non-central nervous system (CNS) systemic embolism.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Advanced Cardiovascular, LLC, Alexander City, Alabama +670 locations
Conditions: Atrial Fibrillation
Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation
Recruiting
Observational, multi-center, clinical device registry for US patients with a primary goal to observe the clinical outcomes in patients who are mapped with Volta Medical's VX1 or AF-Explorer systems during AF ablation procedures.
Gender:
All
Ages:
21 years and above
Trial Updated:
04/22/2024
Locations: Kansas City Cardiac Arrhythmia Research LLC, Overland Park, Kansas +2 locations
Conditions: Atrial Fibrillation
Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation
Recruiting
The purpose of the study is to see if the Sentinel® Cerebral Protection System may prevent occurrence of stroke during an ablation procedure for atrial fibrillation (AF). The secondary purpose of this study is to study if cognitive function after AF ablation differs between those treated with the Sentinel cerebral protection device and those who do not receive the device.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Arrhythmia, Atrial Fibrillation
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
Recruiting
REACT-AF is a multicenter prospective, randomized, open-label, blinded endpoint (PROBE design), controlled trial comparing the current Standard Of Care (SOC) of continuous Direct Oral Anticoagulation (DOAC) use versus time-delimited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) in participants with a history of paroxysmal or persistent Atrial Fibrillation (AF) and low-to-moderate stroke risk.
Gender:
All
Ages:
Between 22 years and 85 years
Trial Updated:
04/18/2024
Locations: University of Southern California - Keck School of Medicine, Los Angeles, California +75 locations
Conditions: Atrial Fibrillation
Left Atrial Appendage Occlusion Registry (LAAO Registry)
Recruiting
The Left Atrial Appendage Occlusion Registry (LAAO Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous and epicardial based left atrial appendage occlusion procedures to reduce the risk of stroke. Patient-level data will be submitted by participating hospitals on a quarterly basis to the American College of Cardiology Foundation's National Cardiovascular Data Registry (NCDR). The primary aims of the LAAO Registry are to opti... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: American College of Cardiology/National Cardiovascular Data Registry (NCDR), Washington, District of Columbia
Conditions: Atrial Fibrillation
Study in Atrial Fibrillation (AF) Patients at High Risk of Stroke
Recruiting
The GARDENIA registry will collect real-world clinical data on the anticoagulant strategies in patients with AF at elevated risk of stroke but also elevated risk of bleeding.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Anthos Investigate Site, Fullerton, California +133 locations
Conditions: Atrial Fibrillation
Amplatzer Amulet LAAO vs. NOAC
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +126 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
Recruiting
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG) or valve surgery.
Gender:
All
Ages:
Between 20 years and 85 years
Trial Updated:
04/15/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Atrial Fibrillation, Post-Op Complication