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Atrial Fibrillation Clinical Trials
A listing of 72 Atrial Fibrillation clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 72
There are currently 72 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Atrial Fibrillation participants are Florida, California, Ontario and Texas.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
SIMPLAAFY Clinical Trial
Recruiting
The primary objective is to demonstrate the safety and effectiveness of two monotherapy regimens versus dual antiplatelet (DAPT) therapy following post-implant with the WATCHMAN FLX Pro device in a commercial clinical setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2025
Locations: University of Alabama Birmingham, Birmingham, Alabama +71 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery
Recruiting
Multinational, investigator-initiated study of oral anticoagulation versus no anticoagulation for the prevention of stroke and other adverse cardiovascular events in patients with transient perioperative atrial fibrillation after noncardiac surgery and additional stroke risk factors.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
06/10/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California +104 locations
Conditions: Stroke, Atrial Fibrillation
Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation
Recruiting
The purpose of the study is to see if the Sentinel® Cerebral Protection System may prevent occurrence of stroke during an ablation procedure for atrial fibrillation (AF). The secondary purpose of this study is to study if cognitive function after AF ablation differs between those treated with the Sentinel cerebral protection device and those who do not receive the device.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/09/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Arrhythmia, Atrial Fibrillation
Mobile Health Technology-Enabled AFib Management
Recruiting
The overall objective of this proposal is to evaluate the effect on quality of life of a comprehensive digital atrial fibrillation (AFib) management tool that will empower patients to a) take an active role in learning about AFib management options, starting and adhering to evidence-based therapies and lifestyle changes and b) to guide the patients during AFib episodes which are associated with anxiety and impairment in quality of life.
Researchers plan to evaluate the effectiveness of this nov... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2025
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland +1 locations
Conditions: Atrial Fibrillation, Behavior
The CONFORM Pivotal Trial
Recruiting
The CLAAS® device will be evaluated for safety and efficacy by establishing its performance is non-inferior to the commercially available WATCHMAN® and Amulet™ left atrial appendage closure devices in patients with non-valvular atrial fibrillation. Patients who are eligible for the trial will be randomized to receive either the CLAAS device or the WATCHMAN or Amulet™ devices and will be followed for 5 years after device implant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/04/2025
Locations: Grandview Medical Center, Birmingham, Alabama +61 locations
Conditions: Atrial Fibrillation, Stroke
Ondansetron for the Management of Atrial Fibrillation
Recruiting
"Afib" is a common irregular heartbeat. Afib can cause stroke, blood clots, dementia and death. Medicines used to treat Afib often do not work well and can cause serious side effects. Clinicians need medicines that work better for Afib. Medicines for Afib work by blocking a current in the heart called a potassium current. There is a newer potassium current called IKas that can contribute to Afib. A medicine called ondansetron is used to keep people with cancer from getting sick to their stomach... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/27/2025
Locations: Indiana Clinical Research Center, Indianapolis, Indiana +2 locations
Conditions: Atrial Fibrillation
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
Recruiting
The purpose of this study is to demonstrate the safety and 12-month effectiveness of the BWI OMNYPULSE™ pulsed field ablation (PFA) platform for pulmonary vein isolation (PVI) in the treatment of participants with symptomatic paroxysmal atrial fibrillation (PAF), an irregular heart rate that causes abnormal blood flow.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/22/2025
Locations: Phoenix Cardiovascular Research Group, Phoenix, Arizona +45 locations
Conditions: Atrial Fibrillation
The Fourth Left Atrial Appendage Occlusion Study
Recruiting
LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite receiving ongoing treatment with oral anticoagulation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/16/2025
Locations: Affinity Hospital dba Grandview Medical Center, Birmingham, Alabama +52 locations
Conditions: Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation
Recruiting
The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Atrial Fibrillation
Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation
Recruiting
This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation. The study will enroll 225 participants. Eligible participants will have undergone sequencing for arrhythmia and cardiomyopathy (CM) genes. Based on those results, participants will be recruited for an outpatient research visit with testing that includes cardiac MRI, rest/stre... Read More
Gender:
ALL
Ages:
15 years and above
Trial Updated:
05/08/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Atrial Fibrillation
Renal Denervation + PVI vs PVI Alone for Persistent AF
Recruiting
Pulmonary vein isolation (PVI) is the cornerstone of ablation for atrial fibrillation (AF). Increased cardiac sympathetic stimulation can facilitate AF and reduction can be accomplished by renal artery denervation (RDN). The recently completed randomized trial, ERADICATE-AF, convincingly demonstrated that RDN plus PVI resulted in a reduction in recurrent incident AF for uncontrolled hypertensives.
This is a randomized controlled pilot trial, "To Evaluate Renal Artery Denervation in Addition to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: University of Rochester, Short Hills, New Jersey
Conditions: Atrial Fibrillation
Pericardiotomy in Cardiac Surgery
Recruiting
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Weill Cornell Medicine, New York, New York +2 locations
Conditions: Atrial Fibrillation, Atrial Flutter, Cardiac Events
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