There are currently 84 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Autism participants are Florida, California, Ontario and Texas.
The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study
NCT04947657
Recruiting
The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden. Secondary objectives of the study are the following: To investigate the impact of catheter ablation on serum pro-thrombotic biomarkers in patients with AF. To correlate coagulation biomarkers with imaging features such as, the degree of fibrosis found on Late Gadolinium Enhancement Magnetic Resonance Imaging (... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
12/20/2023
Locations: Tulane University Medical Center, New Orleans, Louisiana
Conditions: Atrial Fibrillation
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Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
NCT04769310
Recruiting
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention strategies. Instead of relying on non-specific criteria for stroke risk assessment, the investigators propose to identify individuals with high-risk of embolic stroke using imaging criteria that reflect the underlying pathophysiology of embolic stroke of cardiac origin. the inve... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
12/20/2023
Locations: Tulane University Medical Center, New Orleans, Louisiana
Conditions: Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment, Strokes Thrombotic, Stroke, Ischemic
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Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
NCT05014802
Recruiting
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall fibrosis (%) of the left atrial wall area. The investigators hypothesize that patients with a higher baseline Utah fibrosis staging will experience a higher incidence of POAF. The study also aims to evaluate and compare the in-hospital mortality, length-of-stay (LOS), compl... Read More
Gender:
All
Ages:
Between 40 years and 120 years
Trial Updated:
12/20/2023
Locations: Tulane University Medical Center, New Orleans, Louisiana +2 locations
Conditions: Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
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Atrial Fibrosis Progression in Sleep Apnea Patients: A Pilot Study
NCT04814420
Recruiting
The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence and progression of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF). The investigators will also investigate the correlation between OSA metrics (nocturnal oxygen saturation and Apnea Hypopnea Index (AHI)) and degree of fibrosis at baseline and its pro... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
12/20/2023
Locations: Tulane University Medical Center, New Orleans, Louisiana
Conditions: Atrial Fibrillation, Obstructive Sleep Apnea
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The Fourth Left Atrial Appendage Occlusion Study
NCT05963698
Recruiting
LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite receiving ongoing treatment with oral anticoagulation.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Arrhythmia Research Group, Jonesboro, Arkansas +1 locations
Conditions: Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
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Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
NCT05174052
Recruiting
The study will investigate the effect of Dapagliflozin on atrial fibrillation (AF) burden. AF burden will be defined as the percent of time spent in AF over a 2-week period, assessed by noninvasive continuous heart rhythm monitoring at baseline and at 3 months, quality of life (QOL) and validated echocardiographic indices of atrial myopathy. This knowledge will enable us to study the therapeutic potential of SGLT2i as a novel adjunct treatment for patients with DM and AF. Patients with paroxysma... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/12/2023
Locations: University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Atrial Fibrillation, Diabetes Mellitus
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Positron Emission Tomography (PET) Imaging of Thrombosis
NCT03830320
Recruiting
The purpose of the study is to evaluate a new radiotracer called 64Cu-FBP8 for PET-MR imaging of thrombosis. The tracer has the potential of detecting thrombosis anywhere in the body, for instance in the left atrial appendage of patients with atrial fibrillation, and thereby may provide a non-invasive alternative to the current standard-of-care methods.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/01/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Atrial Fibrillation, COVID-19, Cancer, Thrombosis
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Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
NCT02347111
Recruiting
In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will test the hypothesis that a common AF genetic risk allele modulates response to different AADs.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
11/28/2023
Locations: Jesse Brown VA Medical Center, Chicago, Illinois +3 locations
Conditions: Atrial Fibrillation
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COMParison of Algorithms for Rotational Evaluation in Atrial Fibrillation
NCT02997254
Recruiting
This is a cohort study to evaluate algorithms for mapping atrial fibrillation by mapping atrial structure and mapping electrical activity to detect focal and rotational activity.
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Abnormal Heart Rhythms
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The Dynamics of Human Atrial Fibrillation
NCT05366361
Recruiting
Atrial fibrillation (AF) is an enormous public health problem in the United States, affecting 2-5 million Americans and causing rapid heart beats, stroke, heart failure or death. In this project, the applicant will develop a novel framework to better understand human AF that builds on agreement between several concepts for the disease. The applicant will develop strategies to identify AF patients who will best respond to each of several therapies, to guide personalized therapy.
Gender:
All
Ages:
Between 22 years and 80 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
Register for Updates
Machine Learning in Atrial Fibrillation
NCT05371405
Recruiting
Atrial fibrillation is a serious public health issue that affects over 5 million Americans (Miyazaka, Circulation 2006) in whom it may cause skipped beats, dizziness, stroke and even death. Therapy for AF is currently suboptimal, in part because AF represents several disease states of which few have been delineated or used to successfully guide management. This study seeks to clarify this delineation of AF types using machine learning (ML).
Gender:
All
Ages:
Between 22 years and 80 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Arrhythmias, Cardiac
Register for Updates
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2023
Locations: CHI St. Vincent, Arkansas, Little Rock, Arkansas +89 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
Register for Updates