Coronary Artery Disease Clinical Trials

A listing of 63 Coronary Artery Disease clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 63 active clinical trials seeking participants for Coronary Artery Disease research studies. The states with the highest number of trials for Coronary Artery Disease participants are Florida, California, New York and Texas.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

Heart Failure Clinical Trial

Recruiting

You or someone you love may be eligible for a heart failure clinical study. Eligible participants will receive study-related assessments, care, and treatment at no cost. You may be reimbursed for travel while participating. See if you are eligible.

Conditions:

Heart Failure

Congestive Heart Failure

Chronic Heart Failure

Heart Failure

Congestive

Learn More

Myocardial Perfusion Imaging Galmydar Rest/Stress

NCT05625490

Recruiting

A single center, phase 0/1 clinical imaging study designed to assess the role of \[68Ga\]Galmydar PET/CT imaging in human subjects.

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

07/16/2025

Locations: Washington University School of Medicine, Saint Louis, Missouri

Conditions: Coronary Artery Disease

Learn More ›

CTSN Embolic Protection Trial

NCT06027788

Recruiting

This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.

Gender:

ALL

Ages:

60 years and above

Trial Updated:

07/15/2025

Locations: CHI St. Vincent Heart Institute, North Little Rock, Arkansas +27 locations

CHI St. Vincent Heart Institute, North Little Rock, Arkansas

Keck Hospital of the University of Southern California, Los Angeles, California

Emory University, Atlanta, Georgia

Indiana University, Bloomington, Indiana

Indiana Ohio Heart, Fort Wayne, Indiana

Ochsner Clinic, New Orleans, Louisiana

Maine Medical Center, Portland, Maine

Johns Hopkins Medicine, Baltimore, Maryland

University of Maryland, College Park, Maryland

Massachusetts General Hospital, Boston, Massachusetts

University of Michigan, Ann Arbor, Michigan

Mayo Clinic, Rochester, Minnesota

Saint Luke's Hospital of Kansas City, Kansas City, Missouri

Montefiore Medical Center, Bronx, New York

Columbia University Medical Center, New York, New York

New York Presbyterian-Cornell Medical Center, New York, New York

NYU Langone Hospital Brooklyn, New York, New York

Northwell Health, New York, New York

Duke University, Durham, North Carolina

University Hospitals, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

University of Virginia, Charlottesville, Virginia

West Virginia University, Morgantown, West Virginia

London Health Sciences Centre, London, Ontario

University of Ottawa Heart Institute, Ottawa, Ontario

Montreal Heart Institute, Montréal, Quebec

Hôpital Laval, Quebec City, Quebec

Conditions: Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease

Learn More ›

WARRIOR Ancillary Study for CCTA Analysis

NCT05035056

Recruiting

In this study, quantitative characterization of plaque using coronary computed tomographic angiography (CTA) will be used to determine if women who were treated with intensive medical therapy have a greater reduction in the amount and type of cholesterol plaque compared to women receiving usual care and if this results in beneficial changes in clinical symptoms. The study will provide an understanding of how intensive medical therapy works in providing clinical benefit in women with nonobstructi... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/03/2025

Locations: Cedars-Sinai Medical Center, Los Angeles, California

Conditions: Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis, Ischemia

Learn More ›

TECTONIC CAD IVL IDE Study

NCT06885177

Recruiting

A prospective, single-arm, open-label, multi-center IDE study with up to 55 US sites

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/02/2025

Locations: HonorHealth, Scottsdale, Arizona +11 locations

Conditions: Coronary Artery Calcification, Coronary Artery Disease, Stenotic Coronary Lesion

Learn More ›

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

NCT05427370

Recruiting

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 centers comparing revascularization by percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) in patients with multivessel/left main (LM) coronary artery disease (CAD) and reduced left ventricular ejection fraction (LVEF). The primary objective is to determine whether C... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Cedars-Sinai, Los Angeles, California +34 locations

Cedars-Sinai, Los Angeles, California

UofL Health, Inc, Louisville, Kentucky

Mayo Clinic, Rochester, Minnesota

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Medical University of Vienna, Vienna, Not set

Heart Institute, Medical School of the University of Sao Paulo_INCOR, São Paulo, Not set

University of Calgary; Libin Cardiovascular Institute, Calgary, Alberta

Mackenzie Health Sciences Center, Edmonton, Alberta

Fraser Health; Royal Columbian Hospital, New Westminster, British Columbia

Providence Health, Vancouver, British Columbia

Queen Elizabeth II Hospital, Halifax, Nova Scotia

Hamilton General Hospital, Hamilton, Ontario

London Health Sciences Center, University Hospital, London, Ontario

Southlake Regional HC, Newmarket, Ontario

Ottawa Heart Institute, Ottawa, Ontario

Sunnybrook Health Sciences Center, Toronto, Ontario

St. Michael's, Toronto, Ontario

Toronto General Hospital, Toronto, Ontario

Center Hospitalier Universitaire de Montreal, Montréal, Quebec

Montreal Heart Institute, Montréal, Quebec

Hospital Sacre-Coeur, Montréal, Quebec

Institut de Cardiologie Quebec (QC) - Laval, Québec, Quebec

Jilin Heart Hospital, Jilin, Changchun

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Not set

Clinical Hospital Dubrava, Sušak, Zagreb

University Hospital Dusseldorf, Düsseldorf, Not set

G Kuppuswamy Naidu Memorial Hospital (GKNM), Palayam, Tamil Nadu

European Hospital, Via Portuense, Roma, RM

Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, Not set

Medical University of Silesia, Katowice, Not set

Unidade Local de Saude Lisboa Ocidental (ULSLO), Lisboa, Not set

Dedinje Cardiovascular Institute, Belgrade, Not set

Hospital Clinic de Barcelona (ICCV), Barcelona, L'Eixample

Hospital del Vinalopó, Alicante, Not set

Hospital Universitario de Navarra, Pamplona, Not set

Conditions: Coronary Artery Disease, Heart Failure Systolic

Learn More ›

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

NCT05701358

Recruiting

COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI). COMPLETE-2 OCT is a large scale, prospective... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/16/2025

Locations: UCLA, Los Angeles, California +112 locations

UCLA, Los Angeles, California

University of California, San Francisco, San Francisco, California

Cardiovascular Research Institute of Kansas, Wichita, Kansas

The Johns Hopkins University School of Medicine, Baltimore, Maryland

University of Michigan, Ann Arbor, Michigan

Metropolitan Cardiology Consultants / Metropolitan Heart and Vascular Institute (MCC/MHVI), Coon Rapids, Minnesota

RWJ Barnabas Health, Jersey City, New Jersey

Montefiore Medical Center, Bronx, New York

Bassett Medical Center, Cooperstown, New York

VA New York Harbor HealthCare System, New York, New York

NYU Grossman School of Medicine, New York, New York

Cleveland Clinic, Cleveland, Ohio

University of Virginia Medical Center, Charlottesville, Virginia

Westmead Hospital, Westmead, New South Wales

Klinik Floridsdorf, Vienna, Not set

McGill University Health Centre (MUHC), Montréal, Quebec

William Osler Health System, Brampton, Not set

University of Alberta Hospital, Mazankowski Heart, Edmonton, Not set

Hamilton Health Sciences, Hamilton, Not set

Kingston Health Sciences Centre, Kingston, Not set

St. Mary's General Hospital, Kitchener, Not set

London Health Sciences Centre, London, Not set

Centre Hospitalier de l'Universite de Montreal, Montréal, Not set

Hopital du Sacre-Coeur de Montreal, Montréal, Not set

Southlake Regional Health Centre, Newmarket, Not set

Nova Scotia Health, Nova Scotia, Not set

University of Ottawa Heart Institute, Ottawa, Not set

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Not set

Regina General Hospital, Regina, Not set

Royal University Hospital, Saskatoon, Not set

Niagara Health, St. Catharines, Not set

Newfoundland and Labrador Health Services, St. John's, Not set

Thunder Bay Regional Health Sciences Centre, Thunder Bay, Not set

St. Michael's Hospital (Unity Health Toronto), Toronto, Not set

Sunnybrook Health Sciences Centre, Toronto, Not set

Ciusss McQ - Chaur, Trois-Rivières, Not set

St Paul's Hospital, Vancouver, Not set

Vancouver General Hospital, Vancouver, Not set

St. Boniface Hospital, Winnipeg, Not set

St. Anne's University Hospital, Brno, Not set

Aalborg University Hospital, Aalborg, Not set

Aarhus University Hospital, Aarhus, Not set

Rigshospitalet - Copenhagen University Hospital, Copenhagen, Not set

Helsinki University Hospital, Helsinki, Not set

TAYS Sydankeskus Oy, Tampere, Not set

Turku University Hospital, Turku, Not set

St. Vinzenz-Hospital, Cologne, Not set

Helios Amper-Klinikum, Dachau, Not set

Universitatsklinikum Frankfurt, Frankfurt, Not set

Marienkrankenhaus, Hamburg, Not set

Schoen Klink Hamburg, Hamburg, Not set

University Heart & Vascular Center Hamburg, Hamburg, Not set

WKK Heide, Heide, Not set

Gottsegen National Cardiovascular Center, Budapest, Not set

University of Szeged, Szeged, Not set

Lisie Hospital, Ernakulam, Kerala

Meditrina Hospital, Kollam, Kerala

Caritas Hospital Trust, Kottayam, Kerala

Apollo Rajshree Hospitals, Indore, Madhya Pradesh

Rukmani Birla Hospital, Jaipur, Rajasthan

Apollo Hospital, Chennai, Tamil Nadu

The Madras Medical Mission, Chennai, Tamil Nadu

Meenakshi Mission Hospital and Research Center, Madurai, Tamil Nadu

Medicover Hospitals, Hyderabad, Not set

Krishna Institute of Medical Sciences, Secunderabad, Not set

Azienda USL Toscana Sud Est, Arezzo, Not set

UOC Cardiologia - Ospedale Maggiore, Bologna, Not set

Azienda Ospedaliero - Universitaria di Ferrara, Ferrara, Not set

Misericordia Hospital, Grosseto, Not set

Azienda USL-IRCCS di Reggio Emilia, Reggio, Reggio Emilia, Not set

Sant Andrea Hospital - Sapienza University, Rome, Not set

Sorlandet Hospital Arendal, Kristiansand, Arendal

Oslo University Hospital Ulleval, Oslo, Not set

Stavanger University Hospital, Stavanger, Not set

University Hospital Tromso, Tromso, Not set

Provincial Specialized Hospital, Legnica, Dolnoslaskie

Miedziowym Centrum Zdrowia S.A. w Lubinie, Lubin, Dolnoslaskie

Medical University of Warsaw, Warsaw, Mazowieckie

Institute for Cardiovascular Diseases Dedinje, Belgrade, Not set

University Clinical Center of Serbia, Belgrade, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Ramon y Cajal, Madrid, Not set

Hospital Universitario de La Princesa, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Virgen del Rocio, Seville, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Hospital Clinico Universitario de Valladolid, Valladolid, Not set

Karolinska University Hospital, Huddinge, Not set

Lanssjukhuset RYHOV, Jonkoping,, Not set

Karlstad Central Hospital, Karlstad, Not set

Skane University Hospital, Lund, Not set

Danderyd Hospital, Stockholm, Not set

Umeå University Hospital, Umeå, Not set

Uppsala University Hospital, Uppsala, Not set

East Kent Hospitals University NHS Foundation Trust, Ashford, Not set

Blackpool Teaching Hospitals, Blackpool, Not set

Ninewells Hospital, Dundee, Not set

Harefield Hospital, Harefield, Not set

Kettering General Hospital, Kettering, Not set

University Hospitals of Leicester, Leicester, Not set

Liverpool Heart and Chest Hospital, Liverpool, Not set

Barts Health NHS Trust, London, Not set

Imperial College Healthcare NHS Trust, London, Not set

Royal Free London NHS Foundation Trust, London, Not set

Manchester University NHS Foundation Trust, Manchester, Not set

The James Cook University Hospital, Middlesbrough, Not set

Freeman Hospital, Newcastle upon Tyne, Not set

Royal Berkshire Foundation NHS Trust, Reading, Not set

Sheffield Teaching Hospitals, Sheffield, Not set

East and North Hertfordshire NHS Trust, Stevenage, Not set

Royal Cornwall Hospitals NHS Trust, Truro, Not set

The Royal Wolverhampton NHS Trust, Wolverhampton, Not set

Worcestershire Acute Hospitals NHS Trust, Worcester, Not set

Conditions: Acute Myocardial Infarction, Coronary Artery Disease

Learn More ›

A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque

NCT06305559

Recruiting

This placebo-controlled, double-blind, randomized, Phase 3 study is being conducted in adult participants with high-risk atherosclerotic cardiovascular disease (ASCVD) who are not adequately controlled by their maximally tolerated lipid-modifying therapy, to assess the impact of the obicetrapib 10 mg + ezetimibe 10 mg FDC daily on coronary plaque and inflammation characteristics, evaluated using cardiovascular computed tomography angiography (CCTA).

Gender:

ALL

Ages:

45 years and above

Trial Updated:

06/12/2025

Locations: NGMR, Hialeah, Florida

Conditions: Lipidemia, Coronary Artery Disease, Plaque, Atherosclerotic

Learn More ›

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

NCT06445608

Recruiting

This purpose of this trial is to demonstrate 30 day safety and effectiveness outcomes of the KARDION CORY P4 System in subjects who require hemodynamic support during a high-risk PCI procedure.

Gender:

ALL

Ages:

Between 18 years and 90 years

Trial Updated:

06/06/2025

Locations: Dignity Health - Chandler Regional Medical Center, Chandler, Arizona +17 locations

Conditions: Coronary Artery Disease

Learn More ›

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

NCT07016477

Recruiting

The clinical and demographic characteristics of patients undergoing transcatheter aortic valve implantation (TAVI) pose unique challenges for coronary computed tomography (CT) imaging, as this patient population is mainly composed of elderly, frail individuals with severe aortic stenosis, multiple comorbidities, high prevalence of heavily calcified coronary artery disease (CAD) and revascularized coronary arteries. Such vulnerable patients could benefit from a more precise assessment and charact... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/04/2025

Locations: Medical University of South Carolina, Charleston, South Carolina +6 locations

Conditions: Coronary Artery Disease, Aortic Valve Stenosis, Tomography, X-Ray Computed

Learn More ›

Sapphire 3 CTO Study

NCT06358508

Recruiting

A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device performance of the Sapphire 3 0.85, 1.0 and 1.25mm diameter coronary dilatation catheter in predilatation of Chronic Total Occlusion (CTO) lesions during percutaneous coronary intervention. One hundred seventy (170) subjects will be enrolled with a target of one hundred fifty-three (153) evaluable subjects by the angiographic core laboratory at up to 15 clinical sites with t... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/03/2025

Locations: Stanford Health Care, Stanford, California +13 locations

Conditions: Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Heart Diseases, Arteriosclerosis, Cardiovascular Diseases, Chronic Total Occlusion, Chronic Total Occlusion of Coronary Artery

Learn More ›

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

NCT06271590

Recruiting

This is a multicenter, randomized, single-blind pivotal study to evaluate the safety and efficacy of the MagicTouchTM Drug coated balloon in treatment of small vessels in patients with coronary artery disease. The objective is to establish the safety and efficacy of the Magic TouchTM Drug coated balloon in treatment of small vessels (≤2.75 mm). A total of 1605 subjects will be enrolled in a maximum of 50 study sites located in North America. Additional sites located in Europe and South America... Read More

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

05/22/2025

Locations: Dignity Health - Mercy Gilbert Medical Center, Gilbert, Arizona +25 locations

Dignity Health - Mercy Gilbert Medical Center, Gilbert, Arizona

Cedars-Sinai Medical Center, Los Angeles, California

Clearwater Cardiovascular and Interventional Consultants, Clearwater, Florida

University of Florida Health Sciences Center-Jacksonville, Jacksonville, Florida

Tallahassee Research Institute, Tallahassee, Florida

Tampa General Hospital / University of South Florida, Tampa, Florida

Emory University Hospital /Emory School of Medice, Atlanta, Georgia

Atlanta VA Medical Center, Decatur, Georgia

Loyola University Medical Center, Maywood, Illinois

University of Massachusetts Chan Medical School, Worcester, Massachusetts

Minneapolis Heart Institute Foundation (Abbott), Minneapolis, Minnesota

North Mississippi Medical Center, Tupelo, Mississippi

Atlanticare Regional Medical Center, Pomona, New Jersey

Montefiore Medical Center, Bronx, New York

University Hospitals, Cleveland Medical Center, Brooklyn, New York

North Shore University Hospital - Northwell, Manhasset, New York

Icahn School of Medicine at Mount Sinai/ Mount Sinai Hospital, New York, New York

Columbia University, New York, New York

NC Heart and Vascular Research, LLC, Raleigh, North Carolina

University Hospitals, Cleveland Medical Center, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

University of Oklahoma Health Science Center, Oklahoma City, Oklahoma

Providence St. Vincent Medical Center, Portland, Oregon

University of Pittsburgh Medical center (UPMC), Pittsburg, Pennsylvania

Baylor Scott & White The Heart Hospital - Plano, Plano, Texas

West Virginia University Heart & Vascular Institute, Morgantown, West Virginia

Conditions: Coronary Artery Disease, Native Coronary Artery Stenosis, Cardiovascular Diseases

Learn More ›

Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease

NCT06994624

Recruiting

A plant-based diet will be utilized in the treatment of coronary artery disease.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

05/20/2025

Locations: Montgomery Heart & Wellness Center, Houston, Texas

Conditions: Coronary Artery Disease

Learn More ›

13 - 24 of 63