There are currently 71 active clinical trials seeking participants for Coronary Artery Disease research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Texas.
The MATCH Investigation: CT Myocardial Perfusion and CT-FFR vs PET MPI
NCT04316676
Recruiting
The overall goal of this project is to compare the absolute quantification of myocardial perfusion done by using CT myocardial perfusion imaging (CT-MPI) and the coronary flow measured by using CT Fractional Flow Reserve analysis (CT-FFR) to the gold standard represented by PET myocardial perfusion imaging (PET-MPI).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/11/2024
Locations: Emory University Hospital, Atlanta, Georgia
Conditions: Coronary Artery Disease
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Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)
NCT05966662
Recruiting
This investigational device exemption (IDE) study is to assess the safety and effectiveness of the Shockwave Coronary Intravascular Lithotripsy (IVL) System with the Shockwave C2+ 2Hz Coronary IVL Catheter to treat de novo, calcified, stenotic, coronary lesions prior to stenting.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: Heart Center Research, Huntsville, Alabama +11 locations
Conditions: Coronary Artery Disease, Myocardial Infarction
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Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
NCT05360446
Recruiting
CKJX839D12303 is a research study to determine if the study treatment, called inclisiran, in comparison to placebo taken in addition to statin medication can effectively reduce the total amount of plaque formed in the heart's vessels as measured by coronary computed tomography angiography (CCTA) from baseline to month 24. This study is being conducted in eligible participants with a diagnosis of non-obstructive coronary artery disease (NOCAD), where the coronary arteries are blocked less than 50... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/04/2024
Locations: Heart Center Research Llc ., Huntsville, Alabama +102 locations
Conditions: Coronary Artery Disease
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Product Surveillance Registry
NCT01524276
Recruiting
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by streamlining the clinical surveillance process and facilitating leading edge performance assessment via the least burdensome approach.
Gender:
All
Ages:
All
Trial Updated:
03/25/2024
Locations: Not set, Birmingham, Alabama +362 locations
Conditions: Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders, Digestive Disorders, Intracranial Aneurysm, Mechanical Circulatory Support, Respiratory Therapy, Aortic, Peripheral Vascular and Venous Disorders, Minimally Invasive Surgical Procedures, Diagnostic Techniques and Procedures, Surgical Procedures, Operative, Renal Insufficiency, Neurovascular, Coronary Artery Disease, Ear, Nose and Throat Disorder
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MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
NCT05933083
Recruiting
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling. Unfortunately, many patients do not participate in cardiac rehabilitation. Some find it challenging to attend the in-person sessions. This study aims to compare two methods of delivering cardiac rehabilitation: in-person and through telehealth. The investigators want to know if the effects of these two programs are alike and if cer... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: University of California, San Francisco, San Francisco, California +3 locations
Conditions: Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable, Coronary Artery Disease, Heart Transplant
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Liraglutide Effects on Epicardial Fat Inflammatory Genes
NCT03260881
Recruiting
Epicardial adipose tissue (EAT) is the visceral fat of the heart. EAT could locally affect the coronary arteries through local secretion of pro-inflammatory cytokines. EAT plays a role in the development of the coronary artery disease (CAD). EAT is a highly enriched with genes involved in inflammation. Given its rapid metabolism and simple measurability, as first developed by Iacobellis, EAT serves as target for medications targeting the fat. Glucagon-like peptide-1 agonists (GLP-1A) are anti-di... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: University of Miami, Miami, Florida
Conditions: Type2 Diabetes, Coronary Artery Disease
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Mediators of Atherosclerosis in South Asians Living in America
NCT01207167
Recruiting
South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though South Asians represent over one-quarter of the world's population, there are no longitudinal studies in this high-risk ethnic group. The investigators aim to establish a longitudinal study of South Asians at three United States centers to identify risk factors linked to subclinical atherosclerosis and i... Read More
Gender:
All
Ages:
Between 40 years and 84 years
Trial Updated:
03/05/2024
Locations: University of California, San Francisco, San Francisco, California +2 locations
Conditions: Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Coronary Disease
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ELUCIDATE FFRct Study
NCT06018194
Recruiting
The goal of this study is to evaluate the diagnostic accuracy of a novel plaque-based coronary CT angiography (CCTA) fractional flow reserve (FFRct) software device for the estimation of invasive fractional flow reserve (FFR). Researchers will compare the Elucid plaque-based FFRct analysis to invasively measured FFR in patients who have previously undergone CCTA and invasively assessed FFR.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Cardiovascular Medical Group of Southern California, Beverly Hills, California +8 locations
Conditions: Coronary Artery Disease
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Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
NCT05701358
Recruiting
COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI). COMPLETE-2 OCT is a large scale, prospective... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: UCLA, Los Angeles, California +27 locations
Conditions: Acute Myocardial Infarction, Coronary Artery Disease
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CTSN Embolic Protection Trial
NCT06027788
Recruiting
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.
Gender:
All
Ages:
60 years and above
Trial Updated:
02/14/2024
Locations: CHI St. Vincent Heart Institute, North Little Rock, Arkansas +18 locations
Conditions: Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease
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Multicenter Study Into Individualized Scanning for Coronary Artery Disease
NCT04837846
Recruiting
To evaluate intravascular attenuation of the coronary arteries and image quality in an individualized scan and CM injection protocol whereas both scan and injection parameters are tailored to the individual patient in a North American, European and Asian patient population. To evaluate the radiation dose and contrast media dose of this individualized approach for CCTA in an American, European and Chinese patient population. To evaluate the injection parameters required for an average American,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Coronary Artery Disease
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SELUTION 4 De Novo Small Vessel IDE Trial
NCT05946629
Recruiting
Prospective, randomized controlled, single-blind, multicenter, clinical trial to demonstrate the safety and efficacy of the SELUTION SLR 014 PTCA DEB for treatment of de novo lesions in small coronary vessels, defined as reference vessel diameter (RVD) of 2.00 mm to 2.75 mm, in support of a pre-market approval (PMA) application to the United States (US) FDA. The Study will enroll up to 910 randomized subjects, up to 30 subjects in a parallel angiographic substudy, and up to 20 subjects in a par... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/10/2024
Locations: MedStar Washington Hospital Center, Washington, District of Columbia +2 locations
Conditions: Coronary Artery Disease
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