There are currently 71 active clinical trials seeking participants for Coronary Artery Disease research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Texas.
Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health
NCT06055972
Recruiting
This multicenter clustered randomized prospective study will be managed by the American College of Radiology Center for Research and Innovation (ACR CRI). The research team aims to test the efficacy of a patient-centered educational intervention based on coronary artery calcification (CAC) information in cardiovascular risk factor modification of a cohort of patients enrolled in lung cancer screening (LCS) programs across the country.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
01/22/2024
Locations: University of Michagan, Ann Arbor, Michigan +1 locations
Conditions: Coronary Artery Disease, Cardiovascular Diseases, Smoking
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A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction
NCT05332262
Recruiting
Despite the relative safety of PCI with new generation stents, peri-PCI thrombotic complications, including myocardial infarction and myocardial injury, are common in elective PCI, occurring in up to 30% of patients. Importantly, these events are associated with poor prognosis. The risk of peri-PCI myocardial infarction/myocardial injury has been in part attributed to HPR. The aim of this study is to prospectively validate the accuracy of the ABCD-GENE score in identifying stable CAD patients un... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2024
Locations: University of Florida Jacksonville, Jacksonville, Florida
Conditions: Coronary Artery Disease
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The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial
NCT03447938
Recruiting
MICS CABG (Minimally invasive coronary surgery), where coronary artery bypass grafting (CABG) is completed through a small incision over the left chest, has evolved to become a safe and less invasive alternative to conventional sternotomy CABG. Several observational studies have suggested significantly shorter time to return to physical activity for MICS CABG patients compared to sternotomy CABG patients. A randomized study is warranted to validate these findings, provide higher level of evidenc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania +12 locations
Conditions: Coronary Artery Disease
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Polypill in Acute Coronary Syndrome
NCT05514938
Recruiting
Acute coronary syndromes (ACS) represent a major contributor to mortality, morbidity, and healthcare costs. Effective therapies are widely available; however, adherence is low. This contributes to worse patient outcomes and increased risk of morbidity and mortality. The once-daily polypill leverages a population-based strategy that has previously demonstrated efficacy in improving adherence and access to therapy in low-resource settings, making it an innovative approach for improving post-ACS ca... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Acute Coronary Syndrome, Lipid Disorder, Coronary Artery Disease
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The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
NCT05250310
Recruiting
The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/03/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Coronary Artery Disease
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Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
NCT04763200
Recruiting
The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart function and health after a heart procedure compared to the current standard of care.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
12/29/2023
Locations: University of Alabama, Birmingham, Alabama +122 locations
Conditions: Left Ventricular Dysfunction, Coronary Artery Disease
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Etomidate Versus Propofol in CABG Surgery
NCT06068764
Recruiting
The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods. To a... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
12/27/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Coronary Artery Disease
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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120
Recruiting
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocar... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
12/19/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California +102 locations
Conditions: Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
NCT04634240
Recruiting
Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise regarding the management of concomitant CAD in patients undergoing TAVR. Some centers perform routine revascularization with percutaneous coronary intervention (PCI) (either before or after TAVR), while... Read More
Gender:
All
Ages:
All
Trial Updated:
12/13/2023
Locations: Huntsville Heart Center, Huntsville, Alabama +71 locations
Conditions: Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
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Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
NCT05611307
Recruiting
Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant
Gender:
Male
Ages:
Between 18 years and 99 years
Trial Updated:
12/12/2023
Locations: Indiana University, Indianapolis, Indiana
Conditions: Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease, Lipid Disorder, Hypogonadism, Male, Cisplatin Adverse Reaction, Bone Marrow Transplant Complications
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FAME II-10-year Follow-Up
NCT06159231
Recruiting
The FAME-II trial was a prospective, multicenter, multinational, multi-continental, randomized clinical trial with an 'all comers' design. The overall purpose of the FAME-II trial was to compare the clinical outcomes, safety and cost-effectiveness of FFR-guided PCI plus optimal medical treatment (OMT) versus OMT alone in patients with stable coronary artery disease and in whom both PCI and medical treatment can be considered on the basis of the presently existing scientific evidence. FAME-II w... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
12/05/2023
Locations: Stanford University Medical Center, Stanford, California +24 locations
Conditions: Coronary Artery Disease
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A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
NCT06029517
Recruiting
This clinical trial develops and tests a culturally-appropriate educational program (Indigenous SIPin) for reducing sugar-sweetened beverage consumption in men affiliated with Native American athletics communities. Sugary drinks are drinks like pop, soda, and juice. Increased sugar consumption may lead to an increased risk of chronic diseases, including obesity, diabetes, some types of obesity-related cancers, coronary heart disease, hypertension, and dental decay. A culturally sensitive program... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
12/04/2023
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Cardiovascular Disorder, Coronary Artery Disease, Diabetes Mellitus, Obesity-Related Malignant Neoplasm
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