There are currently 65 active clinical trials seeking participants for Coronary Artery Disease research studies. The states with the highest number of trials for Coronary Artery Disease participants are Florida, California, New York and Texas.
Abbott's Coronary IVL IDE Study
NCT06885177
Recruiting
A prospective, single-arm, multi-center Coronary IVL IDE Study with 47 US sites
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: First Coast Cardiovascular Institute, Jacksonville, Florida +3 locations
Conditions: Coronary Artery Calcification, Coronary Artery Disease, Stenotic Coronary Lesion
Register for Updates
Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function
NCT04920799
Recruiting
Older adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The objective of this study is to examine the effect of beet juice supplementation on vascular and inspiratory muscle function in older adults with CAD.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
04/15/2025
Locations: Integrative Cardiovascular Physiology Laboratory, University of Florida, Gainesville, Florida
Conditions: Coronary Artery Disease
Register for Updates
Polypill in Acute Coronary Syndrome
NCT05514938
Recruiting
Acute coronary syndromes (ACS) represent a major contributor to mortality, morbidity, and healthcare costs. Effective therapies are widely available; however, adherence is low. This contributes to worse patient outcomes and increased risk of morbidity and mortality. The once-daily polypill leverages a population-based strategy that has previously demonstrated efficacy in improving adherence and access to therapy in low-resource settings, making it an innovative approach for improving post-ACS ca... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Acute Coronary Syndrome, Lipid Disorder, Coronary Artery Disease
Register for Updates
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
NCT05618353
Recruiting
Heart disease remains the leading cause of death in Veterans. Inflammation in the arteries of the heart may increase the risk of cardiac death. Patients with heart disease undergoing major surgery are at increased risk of complications after surgery, including heart attack, stroke, and death. The proposed research seeks to better understand the role of inflammation in the damage to the heart and blood vessels after major surgery. This research also seeks to identify the potential beneficial role... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2025
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama +5 locations
Conditions: Coronary Artery Disease
Register for Updates
Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study
NCT06821191
Recruiting
Dual antiplatelet therapy (DAPT) with low-dose aspirin and a P2Y12 inhibitor is the current standard of care in patients with coronary artery disease experiencing an acute event or undergoing percutaneous coronary intervention. However, the ischemic benefits are counterbalanced by a significant increase in bleeding events. Over time, different DAPT de-escalation strategies have been developed to reduce the bleeding risk while maintaining the ischemic protection, but there is currently no head-to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: University of Florida, Jacksonville, Florida
Conditions: Coronary Artery Disease
Register for Updates
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD
NCT06713239
Recruiting
PARAMOUNT is a prospective randomized open-label trial testing the hypothesis that a personalized management strategy in symptomatic patients with suspicion of coronary artery disease (CAD), using a CT-based coronary atherosclerotic plaque assessment by AI-enabled quantitative software improves: certainty for diagnosis of CAD, control of CAD risk factors and efficiency of ICA referral with appropriate PCI compared to the usual care strategy based on current AHA/ACC guidelines for care of symptom... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Cardiology Associates of Mobile, Mobile, Alabama +3 locations
Conditions: Coronary Artery Disease
Register for Updates
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120
Recruiting
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocar... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/04/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California +140 locations
Conditions: Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
Register for Updates
Prevail Global Study
NCT06535854
Recruiting
The purpose of the study is to evaluate the clinical safety and efficacy of the Prevail DCB.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Cumc/Nyph, New York, New York +1 locations
Conditions: Coronary Artery Disease
Register for Updates
Product Surveillance Registry
NCT01524276
Recruiting
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by streamlining the clinical surveillance process and facilitating leading edge performance assessment via the least burdensome approach.
Gender:
ALL
Ages:
All
Trial Updated:
03/31/2025
Locations: Not set, Birmingham, Alabama +364 locations
Conditions: Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders, Digestive Disorders, Intracranial Aneurysm, Mechanical Circulatory Support, Respiratory Therapy, Aortic, Peripheral Vascular and Venous Disorders, Minimally Invasive Surgical Procedures, Diagnostic Techniques and Procedures, Surgical Procedures, Operative, Renal Insufficiency, Neurovascular, Coronary Artery Disease, Ear, Nose and Throat Disorder
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Physiological Assessment of Severe Coronary Stenosis for Informing Planned PCI
NCT05491668
Recruiting
Traditionally, the severity of a blockage (stenosis) in a coronary artery has been determined by visual angiographic assessment of the diameter of the artery at the level of a blockage compared to a normal healthy area of the same artery. With the advent of invasive physiological testing to assess coronary blood flow, multiple clinical trials have demonstrated a clinical benefit to a physiology-guided percutaneous coronary intervention (PCI) approach. However, despite this and the potential for... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Coronary Artery Disease
Register for Updates
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
NCT06181240
Recruiting
The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: HCA Florida Largo Hospital, Largo, Florida +16 locations
Conditions: Coronary Artery Disease, Coronary Artery Calcification
Register for Updates
Mediators of Atherosclerosis in South Asians Living in America
NCT01207167
Recruiting
South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though South Asians represent over one-quarter of the world's population, there are no longitudinal studies in this high-risk ethnic group. The investigators aim to establish a longitudinal study of South Asians at three United States centers to identify risk factors linked to subclinical atherosclerosis and i... Read More
Gender:
ALL
Ages:
Between 40 years and 84 years
Trial Updated:
03/24/2025
Locations: University of California, San Francisco, San Francisco, California +2 locations
Conditions: Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Coronary Disease
Register for Updates