There are currently 173 active clinical trials seeking participants for Heart Failure research studies. The states with the highest number of trials for Heart Failure participants are California, Florida, Texas and Pennsylvania.
Early Feasibility Study - Transcatheter Atrial Shunt System
NCT03523416
Recruiting
The purpose of this study is to evaluate initial clinical safety, device functionality and effectiveness of the Edwards Transcatheter Atrial Shunt System.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/05/2023
Locations: UC San Diego Health, La Jolla, California +16 locations
Conditions: Heart Failure
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A Pilot Study to Increase Utilization of GDMT in Patients With HFrEF
NCT05170165
Recruiting
The purpose of this study is to test a clinical decision support (CDS) tool that provides clinicians (cardiologists and nurse practitioners) medication recommendations regarding guideline directed medical therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/30/2023
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Heart Failure
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Personalized Therapy Study - HFRS (TriageHF) Post Approval Study
NCT04489225
Recruiting
Medtronic is sponsoring the HFRS PAS to evaluate the HFRS feature (TriageHF) when used in routine clinical practice following commercial release. The HFRS PAS is conducted within Medtronic's Product Surveillance Registry (PSR) platform.
Gender:
All
Ages:
All
Trial Updated:
08/29/2023
Locations: Alaska Heart, Anchorage, Alaska +112 locations
Conditions: Heart Failure
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Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
NCT04938661
Recruiting
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/28/2023
Locations: University of Minnesota, Minneapolis, Minnesota +1 locations
Conditions: Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention, Heart Failure
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Accuracy of Cardiac Acoustic Biomarkers Recorded by the Wearable Cardioverter Defibrillator
NCT04292405
Recruiting
Evaluate data accuracy of cardiac acoustic biomarkers (CABs) recorded by the Wearable Cardioverter Defibrillator (WCD) as compared to the AUDICOR AM acoustic cardiography recorder.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: MAYO Clinic, Rochester, Minnesota
Conditions: Heart Failure
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Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App
NCT05324566
Recruiting
The purpose of the study is to determine if the Electrocardiograms (ECGs) and symptoms data obtained from an Apple Watch and transmitted to Mayo Clinic are of sufficient quality to guide a person's care.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Heart Failure, Arrhythmias, Cardiac, Health Care Utilization
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Informational Nudge to Improve Heart Failure Prescribing
NCT05986695
Recruiting
This study addresses a critical gap of care for Veterans with heart failure (HF). Only 1/3 or fewer eligible Veterans are receiving recommended SGLT2 and MRA therapies that save lives and prevents HF hospitalizations. The investigators will compare the effect of clinician directed nudges as strategies to improve the health of Veterans with HF.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Southern Arizona VA Health Care System, Tucson, AZ, Tucson, Arizona
Conditions: Heart Failure
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Lymphatic System Stimulation in Heart Failure
NCT05834400
Recruiting
The goal of this pilot clinical trial is to obtain preliminary data on the effects of lymphatic exercise training in patients with heart failure. The main question[s] it aims to answer are: Does performing lymphatic exercise decrease fluid overload symptoms (shortness of breath, lower legs swelling, fatigue), thoracic fluid content, and body fluid level? Does performing lymphatic exercise improve sleep and quality of life (QOL)? Participants with heart failure will be randomly assigned into tw... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2023
Locations: Cooper University Health Care (Cooper), Camden, New Jersey
Conditions: Heart Failure
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Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0
NCT05965934
Recruiting
This study is a multi-center, prospective, randomized (2:1), open-label study to evaluate the safety and efficacy of DSR therapy using the Infusate 2.0 peritoneal solution (composed of 30% icodextrin and 10% dextrose) in diuretic resistant patients with HF and persistent volume overload.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/25/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure, Volume Overload
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A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473
Recruiting
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/24/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy, Heart Failure
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Intra-procedural Transthoracic EChocardiogram to Facilitate Left Bundle Branch Area Pacing (LBBAP)
NCT05646251
Recruiting
The goal of this observational study is to learn more about whether or not the use of heart ultrasound during pacemaker implantation is helpful. The main questions this aims to answer are: Does this help the doctors with figuring out the wire location during implantation? Does this reduce the wire placement procedure time? Does this reduce the x-ray imaging time during the procedure? Participants will be asked to: Have a physical exam and Echocardiogram (ECG) at initial visit, 2 weeks post im... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
07/18/2023
Locations: Geisinger Clinic, Wilkes-Barre, Pennsylvania
Conditions: Heart Failure
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MRI of Myocardial Infarction
NCT03531151
Recruiting
Heart failure (HF) is an enormous health burden affecting approximately 5.1 million people in the US and is the cause of 250,000 deaths each year. Approximately 50% of HF is caused by myocardial ischemia and requires immediate restoration of coronary blood flow to the affected myocardium. However, the success of reperfusion is partly limited by intramyocardial hemorrhage, which is the deposition of intravascular material into the myocardium. Hemorrhagic reperfusion injury has high prevalence and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/17/2023
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Myocardial Infarction, Myocardial Ischemia, Myocardial Injury, Myocardial Fibrosis, Myocardial Reperfusion Injury, Myocardial Edema, Myocardial Necrosis, Heart Failure, Ischemic Heart Disease, Ischemic Cardiomyopathy, Hemorrhage
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