Heart Failure Clinical Trials & Research Studies Near You (Updated 5/25)

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

NCT05714085

Recruiting

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period. The primary hypothesis is that vericiguat is superior to placebo in reducing NT-proBNP at Week 16 of the Base Period.

Gender:

ALL

Ages:

Between 29 days and 17 years

Trial Updated:

05/09/2025

Locations: Loma Linda University Health System ( Site 0008), Loma Linda, California +90 locations

Loma Linda University Health System ( Site 0008), Loma Linda, California

The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 0002), Los Angeles, California

Children's Hospital Colorado ( Site 0012), Aurora, Colorado

Children's National Medical Center ( Site 0020), Washington, District of Columbia

Johns Hopkins All Children's Hospital ( Site 0029), Saint Petersburg, Florida

Children's Healthcare of Atlanta - Arthur M. Blank Hospital ( Site 0001), Atlanta, Georgia

C.S. Mott Children's Hospital ( Site 0033), Ann Arbor, Michigan

Washington University-Pediatric Cardiology/ St. Louis Children's Hospital ( Site 0006), Saint Louis, Missouri

The Children's Hospital at Montefiore ( Site 0030), Bronx, New York

Columbia University Medical Center-Pediatric Cardiology ( Site 0016), New York, New York

Cincinnati Children's Hospital Medical Center ( Site 0034), Cincinnati, Ohio

Cleveland Clinic-Cleveland Clinic Chidren's ( Site 0022), Cleveland, Ohio

Children's Hospital of Philadelphia (CHOP) ( Site 0004), Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh ( Site 0010), Pittsburgh, Pennsylvania

Le Bonheur Children's Hospital ( Site 0007), Memphis, Tennessee

Children's Health-The Heart Center ( Site 0015), Dallas, Texas

Seattle Children's Hospital-Cardiology/Fetal Therapy ( Site 0019), Seattle, Washington

Centre Hospitalier Régional de la Citadelle ( Site 0302), Liège, Liege

UZ Gent ( Site 0301), Gent, Oost-Vlaanderen

UZ Leuven ( Site 0300), Leuven, Vlaams-Brabant

Instituto Dante Pazzanese de Cardiology ( Site 0402), São Paulo, Sao Paulo

Incor - Instituto do Coracao ( Site 0400), Sao Paulo, Not set

Stollery Children's Hospital ( Site 0501), Edmonton, Alberta

Centre intégré universitaire de santé et de services sociaux-Centre de recherche du CHUS ( Site 0502, Sherbrooke, Quebec

Clinica Somer ( Site 0607), Rionegro., Antioquia

Ciensalud Ips S A S ( Site 0608), Barranquilla, Atlantico

Fundación Cardioinfantil Instituto de Cardiología ( Site 0603), Bogotá, Distrito Capital De Bogota

Fundación Valle del Lili ( Site 0604), Cali, Valle Del Cauca

Clínica Imbanaco S.A.S ( Site 0602), Cali, Valle Del Cauca

Rigshospitalet-BørneUngeAfdelingen ( Site 0800), Copenhagen, Hovedstaden

Tampereen yliopistollinen sairaala-Pediatric Early Phase Trials Unit ( Site 0900), Tampere, Pirkanmaa

CHU Bordeaux Haut-Leveque ( Site 1000), Pessac, Aquitaine

CHU Lille - Institut Coeur Poumon ( Site 1005), Lille Cedex, Nord

Centre Hospitalier Universitaire de Nantes - Hôpital Femme-Enfant-Adolescent Chu De Nantes ( Site 10, Nantes, Pays-de-la-Loire

Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone ( Site 1003), Marseille, Provence-Alpes-Cote-d Azur

Hôpital Universitaire Necker Enfants Malades ( Site 1001), Paris, Not set

Assistance Publique - Hopitaux de Paris (AP-HP) - Hopital Robert Debre - Centre Hospitalo Universita, Paris, Not set

Universitaetsklinikum Freiburg ( Site 1102), Freiburg, Baden-Wurttemberg

Universitaetsklinikum Heidelberg ( Site 1100), Heidelberg, Baden-Wurttemberg

Kinderklinik des Uni-Klinikums Erlangen ( Site 1104), Erlangen, Bayern

Medizinische Hochschule Hannover ( Site 1108), Hannover, Niedersachsen

Deutsches Herzzentrum Berlin ( Site 1101), Berlin, Not set

Gottsegen György Országos Kardiovaszkuláris Intézet-Gyermeksziv Kozpont ( Site 1300), Budapest, Not set

Children's Health Ireland (CHI) at Crumlin ( Site 1400), Dublin, Not set

IRCCS Istituto Giannina Gaslini ( Site 1603), Genova, Liguria

A.O.Universitaria Meyer ( Site 1600), Firenze, Toscana

Pusan National University Yangsan Hospital ( Site 2802), Pusan, Kyongsangnam-do

Seoul National University Hospital ( Site 2803), Seoul, Not set

Severance Hospital, Yonsei University Health System ( Site 2800), Seoul, Not set

Samsung Medical Center ( Site 2801), Seoul, Not set

Hospital Universiti Sains Malaysia ( Site 1703), Kota Bharu, Kelantan

University Malaya Medical Centre ( Site 1701), Lembah Pantai, Kuala Lumpur

Hospital Tunku Azizah-Paediatric ( Site 1700), Kuala Lumpur, Not set

Institut Jantung Negara ( Site 1705), Kuala Lumpur, Not set

Instituto Nacional de Pediatria ( Site 1803), Mexico City, Distrito Federal

Morales Vargas Centro de Investigacion ( Site 1810), León, Guanajuato

CINVEC Medica ( Site 1814), Guadalajara, Jalisco

Centro de Atención e Investigación Clínica ( Site 1813), Aguascalientes, Not set

INVECORDIS S.C. ( Site 1808), Hacienda De Las Palmas, Not set

Instituto Nacional de Cardiologia Ignacio Chavez ( Site 1804), Mexico, Not set

Erasmus Medisch Centrum ( Site 1900), Rotterdam, Zuid-Holland

University Medical Center Groningen ( Site 1901), Groningen, Not set

Universitair Medisch Centrum Utrecht ( Site 1902), Utrecht, Not set

Auckland City Hospital ( Site 2000), Auckland, Not set

Instituto Nacional Cardiovascular INCOR Carlos Peschiera Carrillo - EsSalud ( Site 2100), Jesús María, Lima

Uniwersyteckie Centrum Kliniczne-Klinika Kardiologii Dziecięcej i Wad Wrodzonych Serca ( Site 2302), Gdańsk, Pomorskie

Unidade Local de Saude Lisboa Ocidental - Hospital de Santa Cruz ( Site 2401), Lisbon, Lisboa

Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 2402), Lisboa, Not set

Unidade Local de Saúde de São João ( Site 2403), Porto, Not set

National University Hospital-Paediatrics ( Site 2600), Singapore, South West

KK Women's and Children's Hospital ( Site 2601), Singapore, South West

TREAD Research ( Site 2700), Cape Town, Western Cape

Children's Heart Disease Research Unit ( Site 2704), Cape Town, Western Cape

Hospital Sant Joan de Déu-Pediatric cardiology ( Site 2902), Esplugues de Llobregat, Barcelona

Hospital Universitari Vall d'Hebron ( Site 2903), Barcelona, Cataluna

Hospital Materno-Infantil Teresa Herrera ( Site 2905), A Coruna, La Coruna

HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON ( Site 2904), Madrid, Madrid, Comunidad De

Hospital Universitario La Paz ( Site 2912), Madrid, Madrid, Comunidad De

HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO ( Site 2907), Sevilla, Not set

Skånes Universitetssjukhus Lund ( Site 3000), Lund, Skane Lan

Astrid Lindgrens Barnsjukhus ( Site 3001), Stockholm, Stockholms Lan

Faculty of Medicine - Khon Kaen University ( Site 3202), Muang, Khon Kaen

Faculty of Medicine Siriraj Hospital ( Site 3200), Bangkok, Krung Thep Maha Nakhon

Maharaj Nakorn Chiang Mai Hospital-Department of Pediatrics ( Site 3201), Chiang Mai, Not set

Hacettepe Universite Hastaneleri ( Site 3304), Ankara, Not set

Baskent Universitesi Ankara Hastanesi ( Site 3301), Ankara, Not set

Ankara Bilkent Şehir Hastanesi. ( Site 3300), Ankara, Not set

Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi ( Site 3302), Istanbul, Not set

S.B.Ü. DR. BEHÇET UZ ÇOCUK HASTALIKLARI VE CERRAHİSİ EĞİTİM VE ARAŞTIRMA HASTANESİ ( Site 3303), Izmir, Not set

Great Ormond Street Hospital For Children NHS Foundation Trust ( Site 3401), London, London, City Of

Freeman Hospital ( Site 3400), Newcastle upon Tyne, Not set

Conditions: Heart Failure, Left Ventricular Systolic Dysfunction

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Cardiac Power Output in Cardiogenic Shock Patients

NCT05700617

Recruiting

The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/08/2025

Locations: The University of Chicago, Chicago, Illinois

Conditions: Heart Failure, Cardiogenic Shock

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Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

NCT06291922

Recruiting

The goal of this clinical trial is to evaluate the effects of a home-based exercise program using mobile technology on physical activity and capacity, frailty and muscle mass, and quality of life in patients with a newly implanted HeartMate 3 left ventricular assist device (HM3 LVAD). Researchers will compare the effects of an exercise intervention vs. usual care on physical activity and capacity, frailty and muscle mass, and quality of life.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/08/2025

Locations: Henry Ford Health, Detroit, Michigan +3 locations

Conditions: Heart Failure

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Project 2: ACHIEVE- HF

NCT05330221

Recruiting

This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health Inequities by Early PreVEntion in the GREAT LakEs Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/08/2025

Locations: Wayne State University, Detroit, Michigan

Conditions: Heart Failure, Hypertension

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Supporting Health in Veterans With Heart Failure

NCT05839067

Recruiting

This study will test the effectiveness of a culturally-sensitive, telephone-based, tailored problem-solving intervention to improve physical and mental health in Veterans with heart failure (HF). Veterans will be recruited from VA clinics throughout the United States. As a component of this study, Veterans will partner with a registered nurse for a 12-week telehealth program that includes 8 telephone sessions. Follow-up data will be collected at 3-months (post intervention) and 6-, 12-, and 18-m... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/08/2025

Locations: VA Clinic - Gainesville, Gainesville, Florida +3 locations

Conditions: Heart Failure

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Mind Your Heart-II

NCT05431192

Recruiting

This projects studies the role of mindfulness training (MT) to improve self-care among patients with heart failure and cognitive impairment.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/06/2025

Locations: The Miriam Hospital, Providence, Rhode Island

Conditions: Heart Failure, Cognitive Impairment

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Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

NCT06122779

Recruiting

The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HFpEF).

Gender:

ALL

Ages:

Between 40 years and 90 years

Trial Updated:

05/05/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +106 locations

University of Alabama at Birmingham, Birmingham, Alabama

Local Institution - 0096, Lakewood, Colorado

Local Institution - 0077, Jacksonville, Florida

Infinite Clinical Research, Miami, Florida

Local Institution - 0099, Miami, Florida

Local Institution - 0014, Atlanta, Georgia

Local Institution - 0048, Atlanta, Georgia

Bluhm Cardiovascular Institute of Northwestern, Chicago, Illinois

Chicago Medical Research, LLC, Hazel Crest, Illinois

Ascension Medical Group St. Vincent - Indianapolis Heart Care, Indianapolis, Indiana

Local Institution - 0045, Indianapolis, Indiana

St. Louis Heart and Vascular, Saint Louis, Missouri

Local Institution - 0043, Saint Louis, Missouri

Local Institution - 0070, Albany, New York

Local Institution - 0105, Brooklyn, New York

Weill Cornell Medicine, New York, New York

Local Institution - 0059, Rochester, New York

Local Institution - 0076, Rochester, New York

Local Institution - 0094, Rosedale, New York

Local Institution - 0095, Durham, North Carolina

Local Institution - 0058, Cincinnati, Ohio

Local Institution - 0041, Oklahoma City, Oklahoma

South Oklahoma Heart Research, Oklahoma City, Oklahoma

Local Institution - 0078, Abington, Pennsylvania

Tennessee Center for Clinical Trials, Tullahoma, Tennessee

Local Institution - 0104, Austin, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Angiocardiac Care of Texas - PA - PPDS, Houston, Texas

Local Institution - 0051, Houston, Texas

Local Institution - 0066, Falls Church, Virginia

Local Institution - 0060, Ciudad Autónoma de Buenos Aires, Buenos Aires

Local Institution - 0054, General San Martín, Buenos Aires

Local Institution - 0107, Zárate, Buenos Aires

Local Institution - 0090, Córdoba, Cordoba

Local Institution - 0053, Córdoba, Cordoba

Local Institution - 0073, Rosario, Santa FE

Local Institution - 0061, San Miguel De Tucumán, Tucuman

Local Institution - 0067, Ciudad Autonoma de Buenos Aires, Not set

Local Institution - 0068, Ciudad Autónoma de Buenos Aires, Not set

Local Institution - 0074, Córdoba, Not set

Local Institution - 0069, Salta, Not set

Local Institution - 0102, Santa Fe, Not set

Hamilton General Hospital, Hamilton, Ontario

Medicus MFC Inc., Toronto, Ontario

Local Institution - 0030, Toronto, Ontario

Local Institution - 0040, Toronto, Ontario

Local Institution - 0011, Montreal, Quebec

Local Institution - 0035, Trois-Rivieres, Quebec

Peking Union Medical College Hospital, Beijing, Beijing

Local Institution - 0087, Guangzhou, Guangdong

Local Institution - 0080, Luoyang, Henan

Local Institution - 0079, Changsha, Hunan

The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Local Institution - 0106, Rehovot, Not set

Local Institution - 0019, Napoli, Campania

Local Institution - 0023, Milano, Lombardia

Local Institution - 0033, Milano, Lombardia

IRCCS Policlinico San Donato, San Donato Milanese, Lombardia

Local Institution - 0050, San Donato Milanese, Lombardia

Local Institution - 0027, Foggia, Puglia

Local Institution - 0038, Foggia, Puglia

Local Institution - 0052, Massa, Toscana

Local Institution - 0009, Bergamo, Not set

Local Institution - 0017, Pisa, Not set

Local Institution - 0092, Himeji-Shi, Hyogo

Local Institution - 0100, Kanazawa, Ishikawa

Local Institution - 0091, Okayama-Shi, Okayama

Local Institution - 0093, Kishiwada, Osaka

Local Institution - 0103, Takatsuki-Shi, Osaka

Local Institution - 0088, Daegu, Daegu Gwang'yeogsi

Local Institution - 0084, Daejeon, Daejeon Gwang'yeogsi

Local Institution - 0083, Gwangju, Gwangju Gwang'yeogsi

Inha University Hospital, Jung-gu, Incheon Gwang'yeogsi

Local Institution - 0085, Seoul, Seoul Teugbyeolsi

Local Institution - 0055, Seoul, Seoul Teugbyeolsi

Local Institution - 0086, Busan, Not set

Local Institution - 0098, Seongnam-si, Not set

Local Institution - 0081, Seoul, Not set

Clinical Trials UMED Sp. z o.o., Lódz, Lódzkie

Local Institution - 0031, Bialystok, Podlaskie

Local Institution - 0044, Bialystok, Podlaskie

Local Institution - 0020, Lublin, Woj. Lubelskie

Local Institution - 0049, Lublin, Woj. Lubelskie

Local Institution - 0006, Krakow, Not set

Local Institution - 0024, Oswiecim, Not set

Local Institution - 0012, Hospitalet de Llobregat, Barcelona

Local Institution - 0025, Majadahonda, Madrid

Local Institution - 0047, Majadahonda, Madrid

Hospital Universitario Virgen de La Arrixaca, El Palmar, Murcia

Local Institution - 0039, El Palmar, Murcia

Local Institution - 0042, Malaga, Málaga

Local Institution - 0026, Madrid, Not set

Local Institution - 0034, Madrid, Not set

Local Institution - 0032, Malaga, Not set

Hospital Nuestra Señora de Valme, Sevilla, Not set

Local Institution - 0046, Sevilla, Not set

Local Institution - 0010, Valencia, Not set

Local Institution - 0063, Harrow, Greater London

Local Institution - 0071, North Shields, Northumberland

Local Institution - 0062, Oxford, Oxfordshire

Local Institution - 0072, Leeds, Yorkshire

Local Institution - 0057, Sheffield, Yorkshire

Local Institution - 0101, Bristol, Not set

Local Institution - 0097, Dundee, Not set

Local Institution - 0075, London, Not set

Local Institution - 0065, Stockton-On-Tees, Not set

Local Institution - 0064, Wolverhampton, Not set

Conditions: Heart Failure

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Cardiovascular Health Improvement Project

NCT02306200

Recruiting

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Gender:

ALL

Ages:

All

Trial Updated:

05/05/2025

Locations: University of Michigan, Ann Arbor, Michigan

Conditions: Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure, Cardiovascular Diseases

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Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

NCT03970343

Recruiting

The OPTIMIZER Smart Post-Approval Study is a prospective, multi-center, non-randomized, single arm open label study of 620 subjects receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA functional class III symptoms and a left ventricular ejection fraction of 25-45%

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: CardioVascular Associates of Mesa (CVAM), Mesa, Arizona +92 locations

CardioVascular Associates of Mesa (CVAM), Mesa, Arizona

Chan Heart Rhythm Institute (CHRI), Mesa, Arizona

Southwest Cardiovascular Associates, Mesa, Arizona

Banner University Medical Center, Phoenix, Arizona

Cardiovascular Society of Arizona, Phoenix, Arizona

Arizona Cardiovascular Research Center, Phoenix, Arizona

Honor Health, Scottsdale, Arizona

Pima Heart and Vascular Research Center, Tucson, Arizona

University of AZ - Sarver Heart Center, Tucson, Arizona

Cardiovascular Institute of San Diego, Chula Vista, California

NorthBay Health, Heart and Vascular, Fairfield, California

Mid Valley Cardiology - Fresno, Fresno, California

South Orange County Cardiology Group, Laguna Hills, California

University of Southern California - Keck School of Medicine, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

Valley Clinical Trials, Northridge, California

Valley Clinical Trials, Pasadena, California

Torrance Memorial Medical Center, Torrance, California

Aurora Denver Cardiology Associates, Aurora, Colorado

MedStar Washington Hospital Center, Washington, District of Columbia

Heart Rhythm Solutions, Davie, Florida

Florida Memorial Hospital, Jacksonville, Florida

Florida Cardiology, Orlando, Florida

Florida Heart Rhythm Specialist, Plantation, Florida

Piedmont Heart, Atlanta, Georgia

Redmond Regional Medical Center, Rome, Georgia

Advocate Illinois Masonic Medical Center, Chicago, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

OSF Healthcare Cardiovascular Institute, Peoria, Illinois

OSF HealthCare Cardiovascular Institute, Rockford, Illinois

OSF Healthcare Cardiovascular Institute, Urbana, Illinois

Franciscan Physician Network, Indianapolis, Indiana

Ascension St. Vincent, Indianapolis, Indiana

Community Healthcare System, Munster, Indiana

Baptist Lexington, Lexington, Kentucky

University of Kentucky - Gill Heart & Vascular Institute Clinical Research, Lexington, Kentucky

Massachusetts General Hospital, Boston, Massachusetts

Sparrow Clinical Research Institute, Lansing, Michigan

Ascension Providence Park Hospital, Novi, Michigan

St. Joseph Mercy Oakland, Pontiac, Michigan

Ascension Providence Rochester, Rochester, Michigan

Downriver Heart and Vascular, Southgate, Michigan

Trinity Health Michigan Heart, Ypsilanti, Michigan

Minneapolis Heart Institute Foundation - Allina, Minneapolis, Minnesota

St. Louis Heart and Vascular, Bridgeton, Missouri

Logan Health, Kalispell, Montana

Cooper Hospital, Haddon Heights, New Jersey

Virtua Health - Our Lady of Lourdes, Marlton, New Jersey

Morristown Medical Center, Morristown, New Jersey

Jersey Shore University Medical Center, Neptune, New Jersey

Rutgers Medical School, Newark, New Jersey

Valley Hospital, Ridgewood, New Jersey

Mount Sinai Morningside, New York, New York

Mission Health, Asheville, North Carolina

Atrium Health, Charlotte, North Carolina

NC Heart and Vascular Research, Raleigh, North Carolina

TriHealth Hatton, Cincinnati, Ohio

University Hospitals of Cleveland Medical Center, Cleveland, Ohio

The Ohio State University, Columbus, Ohio

Mount Carmel Research institute, Columbus, Ohio

Regional Cardiac Arrythmia Inc., Steubenville, Ohio

ProMedica Health Systems, Toledo, Ohio

Mercy Health - St. Vincent Medical Center, Toledo, Ohio

Oklahoma Heart Hospital, Oklahoma City, Oklahoma

St. Luke's University Health Network, Allentown, Pennsylvania

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania

UPMC Pinnacle Health, Harrisburg, Pennsylvania

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

Penn Medicine Lancaster General Hospital, Lancaster, Pennsylvania

Cardiology Consultants of Philadelphia, Philadelphia, Pennsylvania

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Penn Presybyterian Medical Center, Philadelphia, Pennsylvania

Temple University Hospital, Philadelphia, Pennsylvania

Einstein Medical Center, Philadelphia, Pennsylvania

Allegheny General Hospital, Pittsburgh, Pennsylvania

UPMC Heart and Vascular Institute, Pittsburgh, Pennsylvania

Reading Hospital, Reading, Pennsylvania

Cardiovascular Consultants of Philadelphia, Yardley, Pennsylvania

Texas Cardiac Arrhythmia Research, Austin, Texas

VA North Texas Medical Center, Dallas, Texas

Texan Procedure Center, El Paso, Texas

Baylor College of Medicine, Houston, Texas

UT Health - Memorial Hermann Hospital, Houston, Texas

Heart and Rhythm Institute of South Texas, San Antonio, Texas

UT Health San Antonio, San Antonio, Texas

CHRISTUS Trinity Clinic Research, Tyler, Texas

Centra Health- Lynchburg General Hospital, Lynchburg, Virginia

Bon Secours St. Mary's Hospital, Midlothian, Virginia

HCA Chippenham Hospital, Richmond, Virginia

Richmond VA Medical Center, Richmond, Virginia

CAMC Clinical Trials Center, Charleston, West Virginia

Marshall Cardiology, Huntington, West Virginia

Aurora Research Institute, Milwaukee, Wisconsin

Conditions: Heart Failure

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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

NCT03142152

Recruiting

The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/02/2025

Locations: Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona +68 locations

Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona

Banner Health - Phoenix, Phoenix, Arizona

Tucson Medical Center Health, Tucson, Arizona

Banner University Tuscon, Tucson, Arizona

Memorial Care Hospital, Long Beach, California

Keck School of Medicine of USC, Los Angeles, California

UCLA Medical Center, Los Angeles, California

Stanford University, Redwood City, California

Scripps Health, San Diego, California

University of California- San Francisco, San Francisco, California

South Denver Cardiology, Littleton, Colorado

Medstar, Washington, District of Columbia

University of Miami, Miami, Florida

Advent Health Hospital, Orlando, Florida

Palm Beach Gardens Medical, Palm Beach, Florida

Tallahassee Research Institute, Tallahassee, Florida

Tampa General Hospital, Tampa, Florida

Augusta University Research Institute, Augusta, Georgia

Wellstar Health System,, Marietta, Georgia

Advocate Good Samaritan, Downers Grove, Illinois

Midwest Cardiovascular Institute (MCI), Naperville, Illinois

Prairie Heart Institute, Springfield, Illinois

Community Health Network, Indianapolis, Indiana

Cardiovascular Institute South, Houma, Louisiana

Ochsner Health System, New Orleans, Louisiana

Johns Hopkins, Baltimore, Maryland

St. Elizabeths, Boston, Massachusetts

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess, Boston, Massachusetts

University of Michigan, Ann Arbor, Michigan

Ascension St. Marys Research Institute, Saginaw, Michigan

CentraCare Heart and Vascular, Saint Cloud, Minnesota

Deborah Heart & Lung, Browns Mills, New Jersey

Hackensack University Medical Center, Edison, New Jersey

Albany Medical College,, Albany, New York

University at Buffalo, Buffalo, New York

Vassar Brothers- Hudson Valley Cardiovascular Practice, Poughkeepsie, New York

Lindner Research Center at the Christ Hospital, Cincinnati, Ohio

Harrington Vascular, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

The Ohio State University, Columbus, Ohio

Kettering Health Research Institute, Dayton, Ohio

Oklahoma Heart Institute Hospital, Tulsa, Oklahoma

Saint Francis Hospital,, Tulsa, Oklahoma

Oregon Health & Science University (OHSU), Portland, Oregon

Providence Heart Institute, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Penn Medicine Lancaster General Health, Lancaster, Pennsylvania

University of Pennsylvania, Philadelphia, Pennsylvania

Thomas Jefferson University, Philadelphia, Pennsylvania

Allegheny Health Network, Pittsburg, Pennsylvania

Lankenau Institute of Medical Research, Wynnewood, Pennsylvania

North Central Heart-Avera, Sioux Falls, South Dakota

Centennial Medical Center, Nashville, Tennessee

Henrico Doctors Hospital, Henrico, Virginia

Carilion Hospital, Roanoke, Virginia

Advocate Aurora Research Institute, Milwaukee, Wisconsin

University of Alberta, Edmonton, Alberta

St Boniface Hospital - University of Manitoba, Winnipeg, Manitoba

Toronto General Hospital, Toronto, Ontario

Unity Health Toronto, St Michael's Hospital, Toronto, Ontario

Pole Sante Republique, Clermont Ferrand, Not set

Centre Hospitalier Universitaire De Lille, Lille, Not set

Hôpital Cardiologique Louis Pradel, Lyon, Not set

Clinique du Millènaire Montpelier, Montpellier, Not set

Hôpital Européen Georges-Pompidou, Paris, Not set

European Interbalkan Medical Center, Thessaloníki, Not set

Poznan University of Medical Sciences, Poznan, Not set

St James University Hospital, Leeds, Not set

Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

NCT06526195

Recruiting

The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/01/2025

Locations: Baptist Health Medical Center, Little Rock, Arkansas +24 locations

Conditions: Heart Failure, Heart Diseases, Cardiovascular Diseases, Pulmonary Hypertension

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Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

NCT05601817

Recruiting

This research project is relevant to public health because both heart failure (HF) and mild cognitive impairment (e.g., trouble remembering and concentrating beyond normal aging) are highly prevalent among older adults in the United States. Despite advances in health care, there are no effective interventions for treating cognitive impairment in HF, which if left untreated, leads to suboptimal health, quality of life, and shorter survival. Therefore, the investigators propose to test the effect... Read More

Gender:

ALL

Ages:

55 years and above

Trial Updated:

05/01/2025

Locations: Indiana University, Indianapolis, Indiana

Conditions: Heart Failure, Mild Cognitive Impairment

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Heart Failure Clinical Trials

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