There are currently 173 active clinical trials seeking participants for Heart Failure research studies. The states with the highest number of trials for Heart Failure participants are California, Florida, Texas and Pennsylvania.
Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients
NCT05537467
Recruiting
The study aims to assess the effect of music on the heart resulting in a change in their exercise capacity among systolic heart failure patients undergoing Cardiopulmonary Exercise testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/18/2024
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Heart Failure
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Mobile Integrated Health in Heart Failure
NCT04662541
Recruiting
The purpose of this study is to compare how two different types of care after a hospitalization reduce hospital readmissions and symptom burden. The two types of care are a Transitions of Care Coordinator and Mobile Integrated Health. In the Transitions of Care Coordinator group, participants will receive a phone call from a care coordinator right after they go home following a hospitalization to check in. In the Mobile Integrated Health group, participants will be offered access to a community... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Mount Sinai Health System, New York, New York +2 locations
Conditions: Heart Failure
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Intensive Education Versus Usual Education of Patients for Improving Guideline Directed Medical Therapy (GDMT) Prescription in Heart Failure With Reduced Ejection Fraction- A Randomized Controlled Trial
NCT06273085
Recruiting
The goal of this randomized clinical trial is to test the effect of patient education on extent of use of guideline directed medical treatment (GDMT) of heart failure with reduced ejection fraction. The main question that our study aims to answer is if patient education can improve the adherence to GDMT in heart failure with reduced ejection fraction. Participants will receive educations about GDMT benefits in 1,3 and 5 months after discharge from hospital.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Medstar Union Memorial Hospital, Baltimore, Maryland +3 locations
Conditions: Heart Failure, Patient Acceptance of Health Care
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Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
NCT05972070
Recruiting
The aim of this study is to evaluate feasibility, efficacy, and adherence of home-based cardiac rehabilitation with the integration of telemedicine. Several components will be assessed such as quality-of-life, nutritional counseling, maximum metabolic activity (MET's), diabetic management, tobacco cessation, lipid, blood pressure, and psychosocial management. These tasks will be accomplished through concurrent conversations between patients and their therapist's utilizing telemedicine with obser... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: ROMTech, Brookfield, Connecticut
Conditions: Myocardial Infarction, Percutaneous Transluminal Coronary Angioplasty, Coronary Artery Bypass, Stable Angina, Heart Failure, Valve Disease, Heart, Cardiac Rehabilitation, Stent
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Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial
NCT04419480
Recruiting
Pilot Prospective Randomized Unblinded Pragmatic Trial of Pulmonary Artery Hemodynamic Monitoring Following Hospitalization for Cardiogenic Shock
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: Inova Fairfax Medical Campus, Falls Church, Virginia
Conditions: Cardiogenic Shock, Heart Failure, Ambulatory Hemodynamic Monitoring
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Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure
NCT04999995
Recruiting
Autophagy is considered an important component of Heart failure progression. Deubiquitination enzymes play an important role in autophagy. An important regulatory process within the autophagy pathway is ubiquitination. Ubiquitination targets proteins for degradation. On the contrary, de-ubiquitinating proteins (such as UCHL1) reverses this process. Studies have demonstrated deubiquitination to be linked to certain pathological processes, such as heart failure. UCHL1 will be examined as a potenti... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC, Columbia, South Carolina
Conditions: Heart Failure, Dyspnea; Cardiac
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Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients
NCT06201000
Recruiting
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown further reductions in heart failure hospitalization, cardiovascular events, and mortality, especially for heart failure patients. The SGLT2 gene, also known as SLC5A2 (solute carrier family 5 member 2), is located on chromosome 16 and is responsible for encoding SGLT2. Several SLC5A2 mutations alter SGLT2 expression, membrane location, or transporter function. Several common genetic variations were found in the SLC5A2 gene that may... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/06/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Genetic Polymorphisms, Heart Failure
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RESPONDER-HF Trial
NCT05425459
Recruiting
Multicenter, Prospective, Randomized, Sham Controlled, Double Blinded Clinical Trial, with; 1:1 randomization
Gender:
All
Ages:
40 years and above
Trial Updated:
02/05/2024
Locations: Arizona Cardiovascular Research Center, Phoenix, Arizona +36 locations
Conditions: Heart Failure, Heart Failure, Diastolic
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His Bundle Pacing in Bradycardia and Heart Failure
NCT03008291
Recruiting
Participants in this study will either have heart failure (HF) and are scheduled to undergo pace maker (PM) implantation, cardiac resynchronization therapy pacemaker (CRT-P), cardiac resynchronization therapy defibrillator (CRT-D) implantation, His bundle pacing (HIBP) or left bundle area pacing (LBAP) (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders), or have atrioventricular (AV) block or bradycardia and are scheduled to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Bradycardia, Heart Failure
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Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
NCT05194111
Recruiting
To determine feasibility of recruitment and tolerability of treatment with sacubitril-valsartan among adult age survivors of cancer diagnosed at or before age 39 who have stage B heart failure.
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
01/30/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Heart Failure, Heart Dysfunction
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Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System
NCT04237701
Recruiting
The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: Yale New Haven Health System, New Haven, Connecticut
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Heart Failure NYHA Class IV
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TRISCEND II Pivotal Trial
NCT04482062
Recruiting
Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: SJHMC Heart and Vascular Institute, Phoenix, Arizona +64 locations
Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
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