There are currently 81 active clinical trials seeking participants for Obstructive Sleep Apnea research studies. The states with the highest number of trials for Autism participants are California, Ohio, Pennsylvania and Florida.
Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype
NCT05742360
Recruiting
The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symptom subtype.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/03/2024
Locations: The Ohio State University - Martha Morehouse Medical Pavilion, Suite 2600, Columbus, Ohio +1 locations
Conditions: Obstructive Sleep Apnea
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Increasing Adherence to Oral Appliance Therapy for Obstructive Sleep Apnea
NCT05038215
Recruiting
Obstructive sleep apnea is a chronic condition that has serious health consequences including increased risk of hypertension, type-2 diabetes, heart disease, stroke and reduced life expectancy. This study proposes to use behavioral reinforcement and support to increase adherence to oral appliance therapy for obstructive sleep apnea. The control group in the study will receive routine care. In addition, their oral appliance wear time will be monitored using a sensor built into the appliance. Rout... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2021
Locations: Dental Faculty Practice, Ohio State University, Columbus, Ohio
Conditions: Obstructive Sleep Apnea, Adherence, Patient
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Motivational Enhancement - Acute Decompensated Heart Failure and OSA
NCT04752462
Recruiting
A feasibility randomized controlled trial will be conducted with a 6-month follow up to: Examine the impact of early intensive telemedicine motivational enhancement (TIME) vs standard of care on PAP adherence (n=40/group) and continuity of care at 3 and 6 months post-discharge in patients admitted with ADHF with a new inpatient diagnosis of OSA(REI>5). Assess the effect of early telemedicine integrated with motivational enhancement (TIME) vs standard of care on patient reported outcomes includin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
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Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics
NCT04991389
Recruiting
To create a validated computational tool to predict surgical outcomes for pediatric patients with obstructive sleep apnea (OSA). The first line of treatment for children with OSA is to remove their tonsils and adenoids; however, these surgeries do not always cure the patient. Another treatment, continuous positive airway pressure (CPAP) is only tolerated by 50% of children. Therefore, many children undergo surgical interventions aimed at soft tissue structures surrounding the airway, such as ton... Read More
Gender:
All
Ages:
Between 3 years and 18 years
Trial Updated:
10/23/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Obstructive Sleep Apnea
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A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
NCT05929066
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Central Phoenix Medical Clinic, Phoenix, Arizona +133 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
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PAP for Children With DS and OSAS
NCT04132999
Recruiting
Determine the efficacy of family-informed intervention (INT) vs standard clinical care over a period of twelve months in children with obstructive sleep apnea and Down Syndrome.
Gender:
All
Ages:
Between 6 years and 18 years
Trial Updated:
04/12/2024
Locations: University of Miami, Miami, Florida +2 locations
Conditions: Down Syndrome, Obstructive Sleep Apnea
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Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity
NCT05343000
Recruiting
The purpose of this study is to develop a data driven system for persons with severe obesity sleep apnea that utilizes remote monitoring with health coaching to create behavior changes aimed at improving health and quality of life.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea, Obesity
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Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
NCT06317701
Recruiting
The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team will also determine if the treatment of Obstructive sleep apnea (OSA) by (hypoglossal nerve stimulation) HGNS will alter predictors of cardiovascular outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Obstructive Sleep Apnea
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TipTraQ Home Sleep Test Validation Study
NCT06351878
Recruiting
A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional sleep test, known as polysomnography (PSG), conducted in a sleep center. The performance of the device will then be evaluated by comparing the results from the TipTraQ system with those from the traditional sleep test.
Gender:
All
Ages:
20 years and above
Trial Updated:
04/02/2024
Locations: Duke University, Durham, North Carolina
Conditions: Obstructive Sleep Apnea
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Predictors of Post-COVID Clinical and Cognitive Consequences
NCT06291870
Recruiting
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan
Conditions: Post Acute Sequelae of SARS CoV 2 Infection, Obstructive Sleep Apnea
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Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial
NCT06039865
Recruiting
The goal of this clinical trial in adults with obstructive sleep apnea prescribed positive airway pressure therapy is to test the effects of a new patient-facing consumer wearable-based program (that involves provision of a consumer wearable that measures oxygen levels during sleep plus customized weekly reports to participants). The main question is to learn whether participants' use of positive airway pressure therapy will differ between the participants who receive the new program immediately... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
03/22/2024
Locations: VA Greater Los Angeles Healthcare System, North Hills, California
Conditions: Obstructive Sleep Apnea
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Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
NCT05656365
Recruiting
Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood. Symptoms can include swelling of the glands in the throat, mouth ulcers, and tonsillitis. Removal of the tonsils can stop the periodic flareups. But researchers do not know how PFAPA develops. In this natural history study, researchers will collect specimens and data from people with PFAPA to see what they might have in common. Objective: To coll... Read More
Gender:
All
Ages:
Between 1 month and 99 years
Trial Updated:
03/22/2024
Locations: Children's National Medical Center, Washington, District of Columbia +2 locations
Conditions: Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder, Sleep Disordered Breathing
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