There are currently 80 active clinical trials seeking participants for Obstructive Sleep Apnea research studies. The states with the highest number of trials for Autism participants are California, Ohio, Florida and Pennsylvania.
Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype
Recruiting
The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symptom subtype.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/03/2024
Locations: The Ohio State University - Martha Morehouse Medical Pavilion, Suite 2600, Columbus, Ohio +1 locations
Conditions: Obstructive Sleep Apnea
Increasing Adherence to Oral Appliance Therapy for Obstructive Sleep Apnea
Recruiting
Obstructive sleep apnea is a chronic condition that has serious health consequences including increased risk of hypertension, type-2 diabetes, heart disease, stroke and reduced life expectancy. This study proposes to use behavioral reinforcement and support to increase adherence to oral appliance therapy for obstructive sleep apnea. The control group in the study will receive routine care. In addition, their oral appliance wear time will be monitored using a sensor built into the appliance. Rout... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2021
Locations: Dental Faculty Practice, Ohio State University, Columbus, Ohio
Conditions: Obstructive Sleep Apnea, Adherence, Patient
Motivational Enhancement - Acute Decompensated Heart Failure and OSA
Recruiting
A feasibility randomized controlled trial will be conducted with a 6-month follow up to: Examine the impact of early intensive telemedicine motivational enhancement (TIME) vs standard of care on PAP adherence (n=40/group) and continuity of care at 3 and 6 months post-discharge in patients admitted with ADHF with a new inpatient diagnosis of OSA(REI>5). Assess the effect of early telemedicine integrated with motivational enhancement (TIME) vs standard of care on patient reported outcomes includin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics
Recruiting
To create a validated computational tool to predict surgical outcomes for pediatric patients with obstructive sleep apnea (OSA). The first line of treatment for children with OSA is to remove their tonsils and adenoids; however, these surgeries do not always cure the patient. Another treatment, continuous positive airway pressure (CPAP) is only tolerated by 50% of children. Therefore, many children undergo surgical interventions aimed at soft tissue structures surrounding the airway, such as ton... Read More
Gender:
All
Ages:
Between 3 years and 18 years
Trial Updated:
10/23/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Obstructive Sleep Apnea
Head to Head Comparison of Upper Airway Stimulation and Continuous Positive Airway Pressure; a Pilot Study.
Recruiting
To date, there has been no head to head comparison of Upper Airway Stimulation (UAS) and Continuous Positive Airway Pressure (CPAP) utilizing a full night polysomnographic evaluation. With this study we aim to evaluate a pilot cohort of patients with OSA treated with CPAP or UAS using the WatchPAT polysomnography system.
Gender:
All
Ages:
22 years and above
Trial Updated:
04/19/2024
Locations: Thomas Jefferson University Department of Otolaryngology, Philadelphia, Pennsylvania
Conditions: Obstructive Sleep Apnea
Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea
Recruiting
This study is a prospective, single-arm study conducted under a common implant and follow-up protocol. The objective will be to follow fifty-seven (57) adolescents and young adults (10-21 years of age), with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after undergoing implant of the Inspire Upper Airway Stimulation (UAS) System. The study is being conducted in order to evaluate objective change in cognition and expressive language after implant and t... Read More
Gender:
All
Ages:
Between 10 years and 21 years
Trial Updated:
04/19/2024
Locations: Children's Healthcare of Atlanta/ Emory University School of Medicine, Atlanta, Georgia +7 locations
Conditions: Down Syndrome, Obstructive Sleep Apnea
A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight
Recruiting
The purpose of this study is to is to evaluate the efficacy and safety of retatrutide in participants with type 2 diabetes in participants who have obesity or overweight (J1I-MC-GZBK master protocol) including a subset of participants who have obstructive sleep apnea (OSA) (J1I-MC-GSA2). The study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Pinnacle Research Group, LLC, Anniston, Alabama +92 locations
Conditions: Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Central Phoenix Medical Clinic, Phoenix, Arizona +133 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
PAP for Children With DS and OSAS
Recruiting
Determine the efficacy of family-informed intervention (INT) vs standard clinical care over a period of twelve months in children with obstructive sleep apnea and Down Syndrome.
Gender:
All
Ages:
Between 6 years and 18 years
Trial Updated:
04/12/2024
Locations: University of Miami, Miami, Florida +2 locations
Conditions: Down Syndrome, Obstructive Sleep Apnea
Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity
Recruiting
The purpose of this study is to develop a data driven system for persons with severe obesity sleep apnea that utilizes remote monitoring with health coaching to create behavior changes aimed at improving health and quality of life.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea, Obesity
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
Recruiting
The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team will also determine if the treatment of Obstructive sleep apnea (OSA) by (hypoglossal nerve stimulation) HGNS will alter predictors of cardiovascular outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Obstructive Sleep Apnea
TipTraQ Home Sleep Test Validation Study
Recruiting
A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional sleep test, known as polysomnography (PSG), conducted in a sleep center. The performance of the device will then be evaluated by comparing the results from the TipTraQ system with those from the traditional sleep test.
Gender:
All
Ages:
20 years and above
Trial Updated:
04/02/2024
Locations: Duke University, Durham, North Carolina
Conditions: Obstructive Sleep Apnea