The state of Florida currently has 65 active clinical trials seeking participants for Arthritis research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
Recruiting
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years. Participants will attend study visits and complete subject diaries. Participants will be followed for 6 months after study procedure.
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
05/21/2025
Locations: The Orthopaedic Institute, Gainesville, Florida
Conditions: Osteoarthritis (OA) of the Knee
ZILRETTA in Subjects With Shoulder Osteoarthritis
Recruiting
Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, immediate release (TCA-IR) and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA rel... Read More
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
05/19/2025
Locations: Orthopedic Center of Palm Beach City, Atlantis, Florida +5 locations
Conditions: Glenohumeral Osteoarthritis
The PROACTIVE Study for Black Elders
Recruiting
Chronic musculoskeletal pain (CMP), while a leading cause of physical disablement, is a neglected national health disparity issue in Black communities. The purpose of this study is to test a novel culturally congruent pain self-management intervention. A total of 120 persons aged 50-92, self-identifying as Black or African American having CMP will be invited to participate in this study. The primary outcome measured throughout this 3-year study is movement-evoked pain (MEP).
Gender:
ALL
Ages:
Between 50 years and 92 years
Trial Updated:
05/08/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Musculoskeletal Pain, Chronic Pain, Osteoarthritis, Pain, Chronic, Movement Evoked Pain
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
Recruiting
The purpose of this research study is to evaluate the effectiveness and safety of a permanent embolic (Embosphere Microspheres) for embolization of the geniculate artery for the treatment of moderate to severe knee osteoarthritis.
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
05/05/2025
Locations: University of Miami, Miami, Florida
Conditions: Knee Osteoarthritis
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
Recruiting
The study team is conducting a study to see if Magnesium-L-Threonate (MgT) can help improve how well participants sleep and reduce pain after total joint replacement surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/21/2025
Locations: University of Miami Hospital, Miami, Florida
Conditions: Sleep, Knee Osteoarthritis
ZYNRELEF for Pain Management in Total Knee Arthroplasty
Recruiting
The goal of this randomized controlled trial is to compare opioid medication consumption after surgery for patients who have a total knee replacement. The main questions it aims to answer are: * How well does the study drug control pain in the days after surgery? * Does the study drug reduce the amount of opioid analgesic consumed after surgery? Participants in the study group will undergo a total knee replacement as planned with their surgeon. In addition, be given the study drug, Zynrelef (... Read More
Gender:
ALL
Ages:
Between 35 years and 70 years
Trial Updated:
04/16/2025
Locations: Doctors Hospital, Miami, Florida
Conditions: Post Operative Pain, Osteoarthritis, Knee
Woodcasting Versus Thermoplast Splint in CMC Arthroplasty
Recruiting
This study is a prospective, randomized, nonblinded trial to evaluate patient preference in splints after having a carpometacarpal arthroplasty.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Carpometacarpal (CMC) Joint Arthritis
Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only
Recruiting
The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up to 10 years post-surgery.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/26/2025
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Ankle Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
Exactech Shoulder Post Market Clinical Follow-up Study
Recruiting
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time. This study will follow subjects long-term for a minimum of 10-years, without an early-term restriction on the amount of time they will be followed.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/26/2025
Locations: UF Health Orthopaedics and Sports Medicine Institute, Gainesville, Florida +4 locations
Conditions: Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
Sustained Acoustic Medicine for Osteoarthritis Pain
Recruiting
The purpose of this study is to compare Sustained Acoustic Medicine treatment to topical pain relief gel for the symptomatic management of osteoarthritis. The study will measure pain and function scores for patients undergoing treatment.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
02/24/2025
Locations: James A Haley Veterans Hospital, Tampa, Florida
Conditions: Osteoarthritis
General vs Spinal in Total Joint Arthroplasty (TJA)
Recruiting
The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revision rates.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: University of Miami, Miami, Florida
Conditions: Knee Osteoarthritis, Hip Osteoarthritis
A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
Recruiting
The objectives of this prospective observational cohort study are to evaluate the safety, reliability, reproducibility, and accuracy of the Canary canturioTM te post-TKA.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: Foundation For Orthopaedic Research and Education, Tampa, Florida
Conditions: Knee Osteoarthritis