The state of Florida currently has 63 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
Recruiting
VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes. Approximately 50% of all US Veterans have chronic pain, and CLBP is the most common type of pain in this population. This study will use a sequential randomized, pragmatic, 2-step comparative effectiveness study design. The main goal is to identify the best approach for treating cLBP using commonly recommended non-surgical and non-pharmacological options. The... Read More
Gender:
All
Ages:
All
Trial Updated:
03/21/2024
Locations: Bay Pines VA Healthcare System, Pay Pines, FL, Bay Pines, Florida +1 locations
Conditions: Chronic Low Back Pain
Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Recruiting
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic and debilitating urological complex of disorders characterized by symptoms of bladder pain or discomfort, mostly upon bladder filling, and often accompanied by lower urinary tract symptoms (LUTS). This study will assess how safe and effective BOTOX (onabotulinumtoxinA) is in treating IC/BPS. Adverse events and change in disease symptoms will be evaluated. BOTOX (onabotulinumtoxinA) is an investigational drug being developed for t... Read More
Gender:
Female
Ages:
Between 18 years and 75 years
Trial Updated:
03/21/2024
Locations: Manatee Medical Research Institute /ID# 243859, Bradenton, Florida +1 locations
Conditions: Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
ZYNRELEF for Pain Management in Total Knee Arthroplasty
Recruiting
The goal of this randomized controlled trial is to compare opioid medication consumption after surgery for patients who have a total knee replacement. The main questions it aims to answer are: How well does the study drug control pain in the days after surgery? Does the study drug reduce the amount of opioid analgesic consumed after surgery? Participants in the study group will undergo a total knee replacement as planned with their surgeon. In addition, be given the study drug, Zynrelef (comb... Read More
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
03/19/2024
Locations: Doctors Hospital, Miami, Florida
Conditions: Post Operative Pain, Osteoarthritis, Knee
A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease
Recruiting
This study is an open-label study to evaluate the safety of long-term administration of inclacumab in participants with sickle cell disease (SCD). Participants in this study will have completed a prior study of inclacumab.
Gender:
All
Ages:
12 years and above
Trial Updated:
03/13/2024
Locations: University of South Florida, Department of Pediatrics, Tampa, Florida +4 locations
Conditions: Sickle Cell Disease, Vaso-occlusive Crisis, Vaso-occlusive Pain Episode in Sickle Cell Disease
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: South Lake Pain Institute, Inc, Clermont, Florida +9 locations
Conditions: Chronic Pain
RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: South Lake Pain Institute, Inc, Clermont, Florida +5 locations
Conditions: Pain
Radiofrequency (RF) Ablation Prospective Outcomes Study
Recruiting
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems in the treatment of patients diagnosed with pain and in use for central nervous system (CNS) applications for other disorders.
Gender:
All
Ages:
0 years and above
Trial Updated:
03/08/2024
Locations: The University of Florida Shands, Gainesville, Florida
Conditions: Pain, Chronic
Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/08/2024
Locations: Advanced Urology Institute-Daytona Beach, Daytona Beach, Florida +5 locations
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)
Recruiting
The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/06/2024
Locations: Visionary Investigators Network, Aventura, Florida +9 locations
Conditions: Painful Lumbosacral Radiculopathy
Study to Evaluate Neuromodulation Subject Experience With Contemporary Spinal Cord Stimulation (SCS) Modalities for Chronic Pain
Recruiting
Medtronic, Inc. is sponsoring the SENSE SCS clinical study, a prospective, multi-center, post-market, non-randomized, observational study with a hybrid decentralized model of execution, utilizing a mobile application for the collection of patient reported outcomes (PROs). The purpose of the study is to evaluate workflow of a mobile application for collection of PROs and to gather data on patient experience with spinal cord stimulation therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Pain Management Consultants of Southwest Florida, Fort Myers, Florida
Conditions: Pain, Intractable, Pain, Chronic
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy
Recruiting
MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after herniorrhaphy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Investigator site 211, Miami, Florida +1 locations
Conditions: Acute Pain, Post Operative Pain, Pain
Freedom-1 Study for Chronic Knee Pain
Recruiting
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation. Improvement will be assessed in relation to the clinical outcome measures of pain, with primary endpoint; Pain relief rate as measured by the number of subjects with greater or equal to a 50% decrease in pain on the visual analog scale, comparing baseline to the 1-month follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Holy Cross Hospital, Inc, Fort Lauderdale, Florida +1 locations
Conditions: Osteoarthritic Knee Pain