The state of Florida currently has 70 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
Group Integrative Breathwork for Chronic Pain
NCT06977984
Recruiting
The aim of the proposed research is to iteratively develop, pilot test, and refine an integrative breathwork intervention that is suitable for group delivery to individuals with chronic pain. The intervention will be evaluated for feasibility, acceptability, and plausibility for clinically significant effects in people with chronic musculoskeletal pain.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/27/2025
Locations: University of Florida Clinical Research Center, Gainesville, Florida
Conditions: Chronic Pain
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A Study Assessing the Safety of Cord Blood Product in Sacroiliac Joint Syndrome (SIJ)
NCT06415461
Recruiting
This is a Phase 1 trial. The overall objective is to evaluate the safety and potential efficacy effect of specific type of umbilical cord blood product (CFL001), which, other than specific modifications in manufacturing to render it compatible with current Good Manufacuring Practice (cGMP), is essentially similar to that reported in real-world experience.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
06/26/2025
Locations: University of Florida Pain Clinic, Gainesville, Florida
Conditions: Sacroiliac; Backache, Pain, Back
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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
NCT06628908
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/25/2025
Locations: AMR-Miami, Coral Gables, Florida +12 locations
Conditions: Diabetic Peripheral Neuropathic Pain
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Meditation for Older Adults With Chronic Low Back Pain
NCT06384001
Recruiting
This pilot randomized controlled trial aims to recruit 66 community-dwelling older adults with chronic low back pain and follow up them for 8 weeks. This study aims to test the preliminary effect of a mindfulness-based meditation (MBM) intervention on pain and symptoms among community-dwelling older adults with chronic low back pain, and also to test the effect of the MBM intervention on the host Gut-Brain Axis (GBA).
Gender:
ALL
Ages:
Between 50 years and 89 years
Trial Updated:
06/25/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Chronic Low Back Pain
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Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
NCT05909709
Recruiting
The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects. The study will also examine if the use of the Investigational Product (IP) is able to reduce local inflammation or alleviate Facetogenic back pain
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: The Center for Regenerative Medicine, North Miami, Florida
Conditions: Facet Joints; Degeneration, Back Pain, Facet Joint Pain
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A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: VIN-Julie Schwartzbard, Aventura, Florida +16 locations
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
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Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
NCT06568042
Recruiting
The purpose of this study is to evaluate how safe and how well a treatment works compared to placebo for people with nerve pain that begins in their feet and moves up the leg to just below the knee. Participation may last up to 30 weeks including screening.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: Accel Research Sites - St. Pete-Largo Clinical Research Unit, Largo, Florida +5 locations
Conditions: Neuropathic Pain, Distal Sensory Polyneuropathy
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Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
NCT06619860
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/23/2025
Locations: Accel Research Site - Deland Clinical Research Unit, DeLand, Florida +6 locations
Conditions: Diabetic Peripheral Neuropathic Pain
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Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
NCT03876054
Recruiting
The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2025
Locations: University of Florida Department of Anesthesia, Gainesville, Florida
Conditions: Chronic Pain
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Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI
NCT05630235
Recruiting
The main purposes of this study are to (1) measure the effect of CBD/CBD-A on pain symptoms, pain intensity, pain unpleasantness, and skin sensitivity to hot and cold temperatures; and (2) measure the effect of CBD on brain electrical activity with electroencephalography (EEG).
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
06/16/2025
Locations: Lynn Rehabilitation Center, Miami, Florida
Conditions: SCI - Spinal Cord Injury, Neuropathic Pain
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Brief Mindfulness Intervention for Patients at a Free Acute Care Clinic
NCT07025161
Recruiting
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The clinical effects of a 4-minute audio-recorded mindfulness intervention for 100 English-speaking patients and 100 Spanish-speaking patients at a free acute care clinic will be investigated relative to a 4-minute audio-recoding about pain psychoeducation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Shepherd's Hope Downtown Clinic, Orlando, Florida
Conditions: Pain
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Patient Retrospective Outcomes (PRO)
NCT01550575
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/10/2025
Locations: South Lake Pain Institute, Inc, Clermont, Florida +9 locations
Conditions: Chronic Pain
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