There are currently 852 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics
NCT05819827
Recruiting
The objective of this pilot cohort study is to investigate associations between CIN and changes in gut microbiome composition profiles.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/20/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Bladder Cancer, Prostate Cancer, Testicular Cancer, Bladder Carcinoma, Genitourinary System Carcinoma, Malignant Testicular Neoplasm, Melanoma, Prostate Carcinoma, Sarcoma
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Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes
NCT06401876
Recruiting
The purpose of this research is to obtain blood samples before and after a bariatric procedure to better understand the reasons for glucose intolerance and insulin resistance (diabetes) in the obesity, and the reasons for improvement of diabetes after bariatric surgery
Gender:
All
Ages:
21 years and above
Trial Updated:
05/20/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Glucose Intolerance, Insulin Resistance, Diabetes
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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
NCT03435796
Recruiting
This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one GM T cell infusion will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.
Gender:
All
Ages:
All
Trial Updated:
05/20/2024
Locations: The Mayo Clinic - Jacksonville, Davis-E, Jacksonville, Florida
Conditions: Neoplasms
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Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years
NCT04821310
Recruiting
The purpose of this study is to explore the outcomes, tolerability and safety of 2 different doses of oral pantoprazole (full healing dose, half healing dose), assigned based upon weight, for the maintenance of healing of erosive esophagitis in pediatric participants aged 1 to 17 years with endoscopically-confirmed, healed erosive esophagitis.
Gender:
All
Ages:
Between 1 year and 17 years
Trial Updated:
05/20/2024
Locations: Baptist/Wolfson's Children's Hospital, Jacksonville, Florida +1 locations
Conditions: Esophagitis
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Artisse™ Intrasaccular Device IDE
NCT02998229
Recruiting
The purpose of this study is to assess the safety and effectiveness of the Artisse™ Intrasaccular Device in the treatment of unruptured and ruptured wide-neck bifurcating intracranial aneurysms.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/20/2024
Locations: Baptist Medical Center Jacksonville, Jacksonville, Florida
Conditions: Intracranial Aneurysm
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma
NCT03656536
Recruiting
The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Mayo Clinic-Florida, Jacksonville, Florida
Conditions: Unresectable Cholangiocarcinoma, Metastatic Cholangiocarcinoma
Register for Updates
Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC
NCT05595460
Recruiting
This study aims to determine the safety, preliminary antitumor activity, and pharmacokinetics (PK) of RYZ101 in combination with standard of care (SoC) therapy consisting of carboplatin + etoposide + atezolizumab in untreated subjects with somatostatin receptor expressing (SSTR+) ES-SCLC.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: SCLC,Extensive Stage
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Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer
NCT05563220
Recruiting
This is a multicenter, Phase 1b/2 trial. The phase 1b part of the trial aims to determine the RP2D of elacestrant when administered in combination with alpelisib, everolimus, palbociclib, abemaciclib, and ribociclib. The Phase 2 part of the trial will evaluate the efficacy and safety of the various combinations in patients with ER+/HER2- advanced/metastatic breast cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Mayo Clinic - Jacksonville, Jacksonville, Florida
Conditions: Breast Cancer, Metastatic Breast Cancer
Register for Updates
Anti-Diabetic Medications to Fight PD and LBD
NCT06263673
Recruiting
The purpose of this study is to test the hypothesis that DPP4 inhibitors and SGLT2 inhibitors are well tolerated and have beneficial neurological effects, specifically for Parkinson's disease and Lewy body dementia.
Gender:
All
Ages:
Between 45 years and 65 years
Trial Updated:
05/17/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Lewy Body Dementia, Parkinson Disease
Register for Updates
BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease
NCT05456880
Recruiting
This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating the safety and efficacy of the administration of autologous base edited CD34+ HSPCs (BEAM-101) in patients with severe SCD
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
05/16/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Sickle Cell Disease
Register for Updates
Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL
NCT05153330
Recruiting
A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with KMT2A/ MLL1r, NPM1 mutations), DLBCL, MM, and CLL/SLL.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Mixed-Phenotype Leukemia, Cancer, Refractory, Progression, Diffuse Large B Cell Lymphoma, Multiple Myeloma, Lymphoma, Lymphoma, Non-Hodgkin, Myeloma, Plasma-Cell, Myelomatosis, Plasma Cell Myeloma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Register for Updates
A Study of Virtual Reality During Urological Procedures
NCT05570214
Recruiting
This research is being done to see if virtual reality devices are able to distract patients during Urologic beside vasectomy procedures in the clinic and help improve patient experience and vital signs.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Healthy
Register for Updates