The city of Jacksonville, Florida, currently has 7 active clinical trials seeking participants for Parkinson's Disease research studies.
Anti-Diabetic Medications to Fight PD and LBD
NCT06263673
Recruiting
The purpose of this study is to test the hypothesis that DPP4 inhibitors and SGLT2 inhibitors are well tolerated and have beneficial neurological effects, specifically for Parkinson's disease and Lewy body dementia.
Gender:
All
Ages:
Between 45 years and 65 years
Trial Updated:
04/15/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Lewy Body Dementia, Parkinson Disease
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Globus Pallidus Stimulation to Treat Insomnia
NCT04116996
Recruiting
Researchers are to determine if turning on an additional unilateral DBS (deep brain stimulation) electrode with stimulation to the globus pallidus externa (GPe) region of the brain will improve insomnia (sleep).
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
04/12/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Parkinson Disease
Register for Updates
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
NCT02071134
Recruiting
The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific's commercially available Vercise DBS System in the treatment of Parkinson's disease. The utilization of Image Guided Programming (IGP), and other commercially available programming features, used as planning tools for the programming of patients with Boston Scientific's Vercise DBS System are also evaluated. Additionally, the utilization of the DBS Illumina 3D feature that may be... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Mayo Clinic, Jacksonville, Jacksonville, Florida
Conditions: Parkinson's Disease
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Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
NCT05395624
Recruiting
This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as a biomarker for PET imaging of activated microglia and macrophages in regions of neuroinflammation.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/01/2024
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis (ALS), Parkinson Disease (PD), Alzheimer Disease (AD), Multiple Sclerosis (MS)
Register for Updates
Trial of Parkinson's And Zoledronic Acid
NCT03924414
Recruiting
This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the Nationa... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
07/24/2023
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
Register for Updates
Golf, Physical Rehabilitation, and Movement Disorders
NCT05651776
Recruiting
The importance of physical activity for individuals with movement disorders, including Parkinson disease and Essential tremor, has been established. Barriers including patient engagement continue to limit effectiveness. Golf requires skills found challenging to individuals with movement disorders. This study seeks to assess the feasibility and effectiveness of an outpatient-based rehabilitation program incorporating golf skills and activities on functional measures and quality of life.
Gender:
All
Ages:
Between 18 years and 105 years
Trial Updated:
07/11/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Parkinson Disease, Movement Disorders
Register for Updates
Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder
NCT05307770
Recruiting
The purpose of this research is to compare the efficacy of immediate versus extended-release melatonin as a supplement affecting the sleep cycle in patients with Parkinson disease and Rapid Eye Movement Sleep Behavior Disorder.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Rapid Eye Movement Sleep Behavior Disorder, Parkinson Disease
Register for Updates