There are currently 842 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pre-transplant Health Coaching to Improve Patient-Reported Outcomes in Lung Transplant Candidates
NCT05426200
Recruiting
To examine the effectiveness of an individual health coaching intervention for lung transplant candidates. This intervention will include up to 12 health coaching sessions via phone call over a 12-16 week period. This will be compared to a usual care group the receives pre-transplant care and education alone.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Lung Transplant
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48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer's Disease
NCT04002583
Recruiting
Researchers are trying to determine the frequency of seizures and epilepsy in patients with Early-onset Alzheimer's disease (EOAD) using a 48-hour computer assisted ambulatory electroencephalogram.
Gender:
ALL
Ages:
Between 40 years and 64 years
Trial Updated:
03/25/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Early Onset Alzheimer Disease
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Phase 2 Trial of Voyager V1 in Combination with Cemiplimab in Cancer Patients
NCT04291105
Recruiting
This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will enroll patients with three distinct separate tumor cohorts. The cancers types are colorectal, head and neck carcinoma, and melanoma that are progressing on CPI treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Mayo Clinical, Jacksonville, Florida
Conditions: Melanoma, Head and Neck Squamous Cell Carcinoma, Colo-rectal Cancer
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American Lung Association (ALA) Lung Health Cohort
NCT04543461
Recruiting
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
Gender:
ALL
Ages:
Between 25 years and 35 years
Trial Updated:
03/25/2025
Locations: Nemours Children's Jacksonville, Jacksonville, Florida +1 locations
Conditions: Lung Diseases
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InfasurfAero™ Versus Sham Treatment in Preterm Newborns with RDS
NCT05960929
Recruiting
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.
Gender:
ALL
Ages:
Between 29 weeks and 36 weeks
Trial Updated:
03/25/2025
Locations: University of Florida -Jacksonville, Jacksonville, Florida
Conditions: Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
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SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults with CD33 And/or FLT3 Blood Cancers Including AML/MDS
NCT06325748
Recruiting
This is an open-label study of the safety, biodynamics, and anti-cancer activity of SENTI-202 (an off-the-shelf logic gated CAR NK cell therapy) in patients with CD33 and/or FLT3 expressing blood cancers, including AML and MDS.
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
03/25/2025
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: AML/MDS, CD33 Expressing Hematological Malignancies, FLT3 Expressing Hematological Malignancies
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An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
NCT06378632
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: Jacksonville Center for Clinical Research, Jacksonville, Florida
Conditions: Heart Failure
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Short Course Radiotherapy for the Treatment of Patients with Glioblastoma, SAGA Study
NCT05781321
Recruiting
This phase II trial compares the effect of short course radiotherapy (RT) to standard course RT for the treatment of patients diagnosed with glioblastoma (GBM). The researchers want to learn whether the shorter course treatment is non-inferior (not worse than the standard of care), for patients with GBM. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Short course radiotherapy delivers higher doses of radiation over a shorter per... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/23/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Glioblastoma
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A Study of Virtual Reality and Linaclotide for IBS-C
NCT05796388
Recruiting
The purpose of this study is to determine if adult patients with IBS-C will report an overall greater improvement in IBS symptoms and quality of life when treated with a combination of linaclotide (standard of care medication) and immersive virtual reality (VR) therapy compared to those treated with linaclotide and sham (placebo) VR therapy.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Irritable Bowel Syndrome With Constipation
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Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in Pt. W/ Metastatic PAC
NCT04605913
Recruiting
This is a Phase I/Ib trial, single-center, non-randomized, open-label study of Protein-bound Paclitaxel, Cisplatin, And Gemcitabine (GCN) Combined with Tumor Treatment Fields (TTF) and G+TTF maintenance therapy in patients with metastatic pancreatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Pancreas Cancer, Metastatic Pancreatic Cancer, Pancreatic Adenocarcinoma, Metastatic Adenocarcinoma
Register for Updates
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
NCT06008392
Recruiting
This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells and normal cells in the body. Researchers may request to access these data as they explore how to better prevent, screen, or treat cancer. This study is also being done to create a biobank (library) of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Cancer, Cancer Gene Mutation, PAN Gene Mutation, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Register for Updates
Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH)
NCT05629377
Recruiting
Hypothalamic amenorrhea (HA) occurs during reproductive years and results in stopped menstrual cycles and infertility which can be prolonged from months to years and is characterized by varying combinations of psychosocial stress, anxiety, high levels of physical activity, and/or weight loss. Data from our group indicates that one-third of women with HA (mean age: 27 yrs) have preclinical cardiovascular disease (CVD) measured noninvasively as vascular dysfunction and vascular inflammation. This... Read More
Gender:
FEMALE
Ages:
Between 18 years and 40 years
Trial Updated:
03/18/2025
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Hypothalamic Amenorrhea
Register for Updates