There are currently 823 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
NCT05486143
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: Cancer Specialists of North Florida - Jacksonville, Jacksonville, Florida
Conditions: Breast Cancer
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Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer
NCT04991948
Recruiting
The purpose of the CYAD-101-002 study is to assess the safety and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered concurrently with FOLFOX chemotherapy, followed by pembrolizumab treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2022
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Unresectable Metastatic Colorectal Cancer
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LIPIDS-P Trial Phase I/II
NCT03405870
Recruiting
Briefly, this pilot clinical trial will evaluate preliminary safety and efficacy of the study drug (Smoflipid) at elevating cholesterol levels (primary outcome) in patients with sepsis and moderate organ dysfunction and will also evaluate measures of organ dysfunction, mortality, and biological activity (secondary outcomes).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2022
Locations: Department of Emergency Medicine, UF Health Jax ICU/MICU, Jacksonville, Florida +2 locations
Conditions: Sepsis, Severe, Septic Shock
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Neoadjuvant Multi-epitope HER2 Peptide Vaccine in Patients With HER2-expressing DCIS
NCT03793829
Recruiting
This interventional clinical study will examine the safety and efficacy of a degenerate subdominant HER2 specific helper T cell epitope vaccine (H2NVAC) in patients with HER2-expressing ductal carcinoma in situ (DCIS). The ultimate goal of this vaccine is to prevent future invasive breast cancer among patients who are diagnosed with DCIS. However, the focus of this study is safety and efficacy.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/07/2021
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: DCIS
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Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
NCT04167696
Recruiting
An open-label, phase I, multi-center study to determine in relapsed/refractory (r/r) acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) patients the recommended dose of CYAD-02 after a non-myeloablative preconditioning chemotherapy followed by a potential CYAD-02 consolidation cycle for non-progressive patient. A maximum of 27 r/r AML/MDS patients will be evaluated in this study in case of no dose limiting toxicity (DLT) and no replacement of patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/08/2020
Locations: Mayo Clinic Cancer Center, Jacksonville, Florida
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
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IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
NCT04149496
Recruiting
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.
Gender:
FEMALE
Ages:
Between 18 years and 38 years
Trial Updated:
10/31/2019
Locations: Brown Fertility, Jacksonville, Florida
Conditions: Polycystic Ovary Syndrome
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REtroperitoneal SArcoma Registry: an International Prospective Initiative
NCT03838718
Recruiting
Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma (RPS). Available studies regarding oncologic outcomes are mainly retrospective in nature, and RPS are recognized as a rare disease. Therefore, prospective analysis of high quality data is a top priority. Primary Objectives of this study are: * to prospectively collect standardized clinical data and radiological and pathological material from primary RPS patients treated with surgery at r... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2019
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Retroperitoneal Sarcoma
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