There are currently 841 clinical trials in Jacksonville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Florida, Mayo Clinic - Jacksonville, Mayo Clinic and Mayo Clinic Florida. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
NCT03233191
Recruiting
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.
Gender:
Female
Ages:
Between 45 years and 74 years
Trial Updated:
06/21/2023
Locations: University of Florida Health Science Center - Jacksonville, Jacksonville, Florida
Conditions: Breast Screening
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A Study of Latin Dance for Post- Lung Transplant
NCT05924113
Recruiting
The purpose of this research study is to see if participating in Latin dance for 12 sessions can improve wellbeing in several areas including balance, fear of movement, anxiety, depression and spirometry.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/20/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Lung Transplant, Well-Being, Psychological
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Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
NCT02201992
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Baptist MD Anderson Cancer Center, Jacksonville, Florida
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
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A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC
NCT05491525
Recruiting
The purpose of this study is to evaluate the safety, efficacy, and PK of vibegron in pediatric participants with NDO who are regularly using CIC
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
06/12/2023
Locations: Nemours Childrens Health, Jacksonville, Jacksonville, Florida
Conditions: Neurogenic Detrusor Overactivity
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A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery
NCT05814016
Recruiting
The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
06/09/2023
Locations: Mayo Clinic Jacksonville - PPDS, Jacksonville, Florida
Conditions: Sleep Apnea
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Fycompa in Catamenial Epilepsy
NCT05201703
Recruiting
The purpose of the proposed investigation is to carry out a pilot study of add-on perampanel (Fycompa) in women with perimenstural (C1) catamenial epilepsy. Perampanel, a noncompetitive AMPA receptor antagonist, is uniquely positioned to decrease progesterone receptor mediated excitotoxicity. This mechanism of action would allow a novel use of perampanel as an effective treatment of C1 catamenial epilepsy.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
06/07/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Catamenial Epilepsy
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Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)
NCT04296903
Recruiting
The ApiFix MID-C System is a unidirectional expandable rod, designed to be connected unilaterally to the spine via 2 anchor points on the concave side of a scoliotic deformity above and below the apex of the major curvature to treat adolescent idiopathic scoliosis. The MID-C System is designed to act as an internal brace. Patients implanted with the device in the US within 2 years of FDA's approval of H17001 should be enrolled in the study. A minimum number of 200 patients will be enrolled in th... Read More
Gender:
All
Ages:
10 years and above
Trial Updated:
06/05/2023
Locations: Wolfson children's hospital, Jacksonville, Florida
Conditions: Adolescent Idiopathic Scoliosis
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Tailoring P2Y12 Inhibiting Therapy in Patients Requiring Oral Anticoagulation After PCI
NCT04483583
Recruiting
Clopidogrel is the P2Y12 inhibitor of choice in PCI patients requiring OAC. However, concerns have been raised based on the notion that a considerable number of patients may have inadequate response to clopidogrel. Although practice recommendations indicate that the use of potent P2Y12 inhibitors (i.e., ticagrelor) may be considered in patients at increased thrombotic risk, they do not recommend routine testing to identify patients with poor response to clopidogrel. The aim of this study is to a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Coronary Artery Disease
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Integrating Data, Algorithms and Clinical Reasoning for Surgical Risk Assessment
NCT02741986
Recruiting
Brief Summary: The goal of this study is to implement and test an intelligent perioperative system (IPS) that in real-time predicts risk for postoperative complications using routine clinical data collected in electronic health records. The accuracy of computer-generated risk scores will be compared to physician's risk scores for the same patients. Physicians will be also asked to provide the opinion regarding the computer-generated risk scores using interactive interface with the program. The i... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/04/2023
Locations: UF Health Jacksonville, Jacksonville, Florida
Conditions: Postoperative Complications
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Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia
NCT04447989
Recruiting
This is a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study of sildenafil in premature infants (inpatient in Neonatal Intensive Care Units (NICUs)) with severe bronchopulmonary dysplasia (BPD).
Gender:
All
Ages:
29 weeks and below
Trial Updated:
06/02/2023
Locations: University of Florida Jacksonville Shands Medical Center, Jacksonville, Florida +1 locations
Conditions: Bronchopulmonary Dysplasia of Newborn
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Role and Mechanisms of Lipid and Lipoprotein Dysregulation in Sepsis
NCT04576819
Recruiting
Lipids and lipoproteins (cholesterol and lipid metabolites) are present in sepsis and are highly biologically active regulators of inflammation, but currently the changes in lipid and lipoprotein homeostasis during sepsis are not well understood. This project will investigate the changes in lipid and lipoprotein function, oxidation, metabolites, and changes in gene expression to further our understanding of dysregulated lipid and lipoprotein metabolism in sepsis. We will analyze a bank of sample... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/30/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Sepsis, Shock, Septic
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Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder
NCT05307770
Recruiting
The purpose of this research is to compare the efficacy of immediate versus extended-release melatonin as a supplement affecting the sleep cycle in patients with Parkinson disease and Rapid Eye Movement Sleep Behavior Disorder.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2023
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Rapid Eye Movement Sleep Behavior Disorder, Parkinson Disease
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