The city of Miami, Florida, currently has 15 active clinical trials seeking participants for Healthy research studies.
Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1
NCT06381102
Recruiting
The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/19/2024
Locations: University of Miami, Miami, Florida
Conditions: Healthy
Register for Updates
A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
NCT06132126
Recruiting
The main purpose of this study is to assess the safety and tolerability of a single dose of LY3938577 in healthy participants and participants with Type 2 Diabetes Mellitus (T2DM) (Part A) and multiple doses of LY3938577 in participants with T2DM (Part B). The study will last approximately 6 weeks for Part A and approximately 10 weeks for Part B respectively.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/18/2024
Locations: Qps-Mra, Llc, Miami, Florida
Conditions: Healthy, Type 2 Diabetes Mellitus
Register for Updates
A Study of LY3437943 in Participants With Impaired and Normal Liver Function
NCT05916560
Recruiting
The main purpose of this study is to measure how much of LY3437943 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to healthy participants with normal liver function. The safety and tolerability of LY3437943 will also be evaluated. The study may last up to 9 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/25/2024
Locations: Advanced Pharma Clinical Research, Miami, Florida
Conditions: Healthy, Hepatic Insufficiency
Register for Updates
Brain Changes in Psoriasis After Secukinumab Treatment
NCT04717466
Recruiting
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception of well-being, itch, and pain in participants with psoriasis.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2024
Locations: University of Miami, Miami, Florida
Conditions: Psoriasis, Healthy
Register for Updates
A Phase 1a Study of PMN310 In Healthy Volunteers
NCT06105528
Recruiting
This first in human Phase 1a clinical trial will evaluate the safety, tolerability, and pharmacokinetics of a single IV infusion of PMN310 in healthy volunteers.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/16/2024
Locations: Clinical Pharmacology of Miami, LLC, Miami, Florida
Conditions: Healthy Participants
Register for Updates
Study of a Respiratory Syncytial Virus/Human Metapneumovirus Vaccine Candidate
NCT06134648
Recruiting
The purpose of this study is to assess the safety and immunogenicity of a single intramuscular (IM) injection of different doses of an respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) vaccine candidate, in adult participants aged 60 years and older. In addition, the study will evaluate the safety and immunogenicity of a booster vaccination administered 12 months after the primary vaccination in a subset of the study population.
Gender:
All
Ages:
60 years and above
Trial Updated:
02/08/2024
Locations: Suncoast Research Associates, LLC Site Number : 8400002, Miami, Florida
Conditions: Respiratory Syncytial Virus Infection, Healthy Volunteers, Human Metapneumovirus
Register for Updates
A Study of LY3502970 in Participants With Impaired and Normal Liver Function
NCT05882032
Recruiting
The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to participants with normal liver function. The safety and tolerability of LY3502970 will also be evaluated. The study may last up to 6 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/29/2024
Locations: Clinical Pharmacology of Miami, Miami, Florida
Conditions: Healthy, Hepatic Insufficiency
Register for Updates
A Study of TAK-279 in Adults With or Without Liver Damage
NCT05976321
Recruiting
The main aim of this study is to find out how the body processes 1 dose of TAK-279 (pharmacokinetics) in participants with liver problems compared to participants without liver problems. Other aims are to check for side effects from TAK-279 and to learn how well participants tolerate 1 dose of TAK-279. The participants will need to stay at the clinic for 11 days.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: University of Miami, Miami, Florida
Conditions: Hepatic Impairment, Healthy Volunteers
Register for Updates
A Study of TAK-279 in Adults With or Without Kidney Problems
NCT05992155
Recruiting
The main aim of this study is to find out how the body processes 1 dose of TAK-279 (pharmacokinetics) in participants with kidney problems compared to participants without kidney problems. Other aims are to check for side effects from TAK-279 and to learn how well participants tolerate 1 dose of TAK-279. The participants will need to stay at the clinic for 11 days.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Clinical Pharmacology of Miami, Miami, Florida
Conditions: Renal Impairment, Healthy Volunteers
Register for Updates
A Study Investigating Lu AG06474 in Healthy Young Participants
NCT05943327
Recruiting
The purpose of this study is to investigate the safety of multiple oral doses of Lu AG06474, how well the doses are tolerated, and what the body does to the drug after administering it to healthy young participants. This study also aims to compare how the body absorbs and uses Lu AG06474 when it is given in capsule form versus when it is given as an oral solution.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
08/02/2023
Locations: Quotient Sciences Miami, Miami, Florida
Conditions: Healthy Participants
Register for Updates
With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
NCT05721976
Recruiting
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic female cancer survivors and adult daughters.
Gender:
Female
Ages:
21 years and above
Trial Updated:
07/12/2023
Locations: University of Miami, Miami, Florida
Conditions: Cancer, Breast, Cancer, Uterus, Cancer, Ovary, Obesity, Activity, Motor, Diet, Healthy
Register for Updates
A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
NCT05901714
Recruiting
This study will consist of 2 parts. The study will evaluate whether administration of phenytoin impacts the single-dose drug levels of afimetoran and BMT-271199 (Part 1) and will evaluate whether multiple administrations of afimetoran impact the drug levels of midazolam and 1-hydroxymidazolam (Part 2).
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
07/12/2023
Locations: Syneos Health Clinical Research Services, Llc, Miami, Florida
Conditions: Healthy Participants
Register for Updates