There are currently 1290 clinical trials in Miami, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Miami, GSK Investigational Site, University of Miami Miller School of Medicine-Sylvester Cancer Center and University of Miami Miller School of Medicine. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
NCT06293898
Recruiting
The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-M07D1 in patients with HER2 expressing advanced tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2025
Locations: University of Miami, Miami, Florida
Conditions: Endometrial Cancer, Cervical Cancer, Ovarian Cancer, Urothelial Carcinoma, Biliary Tract Cancer, Breast Cancer, Lung Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, Esophageal Cancer
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A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
NCT06752668
Recruiting
Narcolepsy Type 1 (NT1), Narcolepsy Type 2 (NT2), and Idiopathic Hypersomnia (IH) are rare conditions that make people feel very sleepy during the day (often referred to as excessive daytime sleepiness \[EDS\]). People living with these conditions might find it hard to stay alert and pay attention when they are at school, working, driving, or performing other daily activities. While all conditions result in feeling sleepy, there are some differences in other common symptoms: * NT1: People with... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/30/2025
Locations: Miami, Florida, Miami, Florida +1 locations
Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
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Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma
NCT03618550
Recruiting
The purpose of this study is to test any good and bad effects of the study drug, pembrolizumab, in combination with GVD in the treatment of Hodgkin lymphoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2025
Locations: University of Miami, Miami, Florida
Conditions: Hodgkin Lymphoma, Relapsed or Refractory Hodgkin Lymphoma
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Spinal Cord Injury Model Systems (SCIMS) - Education Module
NCT06003686
Recruiting
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2025
Locations: University of Miami - Miami Project to Cure Paralysis, Miami, Florida
Conditions: Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
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Opioid, HIV and Immune System
NCT04304768
Recruiting
The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people opioid and non opioid users to understand how opioid affect the immune responses (body defenses against infection) to the flu vaccine.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
05/28/2025
Locations: University of Miami, Miami, Florida
Conditions: Immune Defect
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Tfh Dysfunction in HIV and Aging
NCT04487041
Recruiting
The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people to understand how aging and HIV infection affect the immune responses (body defenses against infection) to the flu vaccine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: University of Miami, Miami, Florida
Conditions: Human Influenza
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Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794
Recruiting
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
05/28/2025
Locations: University of Miami, Miami, Florida
Conditions: Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
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A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia
NCT05865028
Recruiting
The purpose of this study is to assess whether APG-157 can reduce the tumor size in participants with the study disease. Another purpose is to find out about the effects of APG-157 on certain tumor markers and oral rinses in participants with the study disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: University of Miami, Miami, Florida
Conditions: Oropharyngeal Dysplasia, Oral Cavity Dysplasia, Oral Carcinoma in Situ
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An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
NCT06073132
Recruiting
The proposed Phase 2/3 trial with double-blind and open-label extension phases is an international, multicenter study designed to assess the efficacy and safety of diacerein 1% ointment in patients with generalized EBS.
Gender:
ALL
Ages:
6 months and above
Trial Updated:
05/28/2025
Locations: Pediatric Center of Excellence (PCE) - Miami Pediatric Endocrinology, LLC, Miami, Florida
Conditions: Generalized Epidermolysis Bullosa Simplex
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Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics
NCT06109441
Recruiting
ALTB-268-201 is a Phase 2a, multicenter, single arm, multiple-dose, open-label study evaluating the efficacy and safety of ALTB-268 in subjects with moderately to severely active UC. The study consists of a Screening Phase, an Induction Phase, a Maintenance Phase, and an OLE.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/28/2025
Locations: Gastro Health Research, Miami, Florida
Conditions: Ulcerative Colitis
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Adjuvant Quisinostat in High-Risk Uveal Melanoma
NCT06932757
Recruiting
The purpose of this study is to see if giving participants quisinostat will prevent participants' uveal melanoma tumor from spreading. The researchers want to find out the effects that quisinostat has on participants' condition.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/28/2025
Locations: University of Miami, Miami, Florida
Conditions: Uveal Melanoma
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HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis
NCT06001385
Recruiting
The goal of this clinical trial is to determine the effectiveness of Reduced Dose Post-Transplant Cyclophosphamide (PTCy) in patients with hematologic malignancies after receiving an HLA-Mismatched Unrelated Donor (MMUD) . The main question\[s\] it aims to answer are: * Does a reduced dose of PTCy reduce the occurrence of infections in the first 100 days after transplant? * Does a reduced dose of PTCy maintain the same level of protection against Graft Versus Host Disease (GvHD) as the standard... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/27/2025
Locations: University of Miami Sylvester Cancer Center, Miami, Florida
Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myeloproliferative Neoplasm, Lymphoma, Chronic Myelomonocytic Leukemia, Pro-Lymphocytic Leukemia, Myelofibrosis
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