There are currently 1290 clinical trials in Miami, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Miami, GSK Investigational Site, University of Miami Miller School of Medicine-Sylvester Cancer Center and University of Miami Miller School of Medicine. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
NCT04582383
Recruiting
Acne is common illness of adolescents and young adults which is associated with substantial morbidity. While topical treatments are often sufficient for mild acne, moderate to severe acne often requires treatment with systemic medications such as oral antibiotics, hormonal therapies such spironolactone, and isotretinoin. Sebum overproduction is fundamental to the pathogenesis of acne with associated disordered keratinization and subsequent microbial colonization and inflammation resulting in the... Read More
Gender:
Female
Ages:
Between 16 years and 40 years
Trial Updated:
11/01/2023
Locations: University of Miami, Miami, Florida +1 locations
Conditions: Acne
Register for Updates
Supporting Treatment Adherence for Resilience and Thriving (START)
NCT05140876
Recruiting
This Phase II randomized controlled trial is testing the efficacy of a cell phone application called START for helping men who use stimulants like methamphetamine to get the most out of their HIV treatment.
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/01/2023
Locations: University of MIami Miller School of Medicine, Miami, Florida
Conditions: Adherence, Medication, HIV-1-infection, Stimulant Use
Register for Updates
Cultural Adaptation of a SSI for Youth Anxiety
NCT04729504
Recruiting
The overarching objective of this protocol is to (1) adapt and (2) disseminate an evidence-based, brief (approximately 30 minute) single session intervention (SSI) to better reflect the cultural and linguistic diversity of Latin, Haitian, and Haitian-American individuals via a fully online platform.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: University of Miami, Miami, Florida
Conditions: Anxiety Disorders
Register for Updates
A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
NCT06112340
Recruiting
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled in the prior VGN-TED-301 through Week 24. These subjects include VGN-TED-301 Week 24 proptosis non-responders or subjects who relapse during the Follow-Up Period of VGN-TED-301.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: Bascom Palmer Eye Institute, Miami, Florida
Conditions: Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases, Thyroid Associated Ophthalmopathy, Graves Ophthalmopathy, Thyroid Diseases, Orbital Diseases, Proptosis, IGF1R, Exophthalmos, Hashimoto
Register for Updates
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
NCT05666960
Recruiting
The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-3750) in patients with mild to moderate ulcerative colitis. Patients will take an oral dosage of probiotic (R-3750) and provide patient-reported and physician scored measures of their colitis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-3750) on fecal levels will also be measured.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/31/2023
Locations: AP Medical Research LLC, Miami, Florida
Conditions: Ulcerative Colitis Chronic Mild, Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic, Ulcerative Colitis
Register for Updates
Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain
NCT06010251
Recruiting
The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/31/2023
Locations: University of Miami, Miami, Florida
Conditions: Spinal Cord Injuries, Neuropathic Pain
Register for Updates
Functional Sucrase Deficiency in Short Bowel Syndrome Patients With Intestinal Failure
NCT04604275
Recruiting
Short gut syndrome with intestinal failure patients may have decreased production of disaccharidases, like sucrase, an enzyme responsible for digesting sugar in foods. This can happen due to loss of bowel length from surgery or from loss of cellular function in the intestines due to use of parenteral nutrition intravenously. Therefore, patients with these conditions may not be able to digest sucrose (sugar) fully. Patients might experience abdominal distension/pain, vomiting and diarrhea when su... Read More
Gender:
All
Ages:
All
Trial Updated:
10/31/2023
Locations: Jackson Memorial Hospital, Miami, Florida +1 locations
Conditions: Short Gut Syndrome
Register for Updates
Preventing Anxiety and Depression in Older Hispanics
NCT03870360
Recruiting
The purpose of this study is to look at the best ways to prevent anxiety and depression in older Latino adults who are at risk for developing anxiety and depression. Participants will be randomized to either a health promotion intervention or a healthy lifestyles education program.
Gender:
All
Ages:
60 years and above
Trial Updated:
10/30/2023
Locations: University of Miami, Miami, Florida
Conditions: Depression, Anxiety
Register for Updates
Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis
NCT05203939
Recruiting
This is a Phase 1/2 Study to Assess the Safety and Efficacy of OCU400 in patients with retinitis pigmentosa associated with NR2E3 and RHO mutations and in patients with LCA due to mutation(s) in CEP290 gene (OCU400-101). To document prospective eye pathology in the above subjects Investigators will also conduct a Natural History Study (OCU400-104)i This is a multicenter study, which will be conducted in two phases and will enroll up to a total of 24 subjects in the OCU400-101 and 100 subjects i... Read More
Gender:
All
Ages:
6 years and above
Trial Updated:
10/24/2023
Locations: Ocugen Site 3 - Bascom Palmer Eye Institute, Miami, Florida
Conditions: Retinitis Pigmentosa, Leber Congenital Amaurosis
Register for Updates
A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases
NCT04554914
Recruiting
The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.
Gender:
All
Ages:
All
Trial Updated:
10/23/2023
Locations: Sylvester Comprehensive Cancer Center/ University of Miami, Miami, Florida
Conditions: Epstein-Barr Virus (EBV)-Associated Diseases, EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications, EBV+ Sarcomas, Leiomyosarcoma, EBV+ Lymphoproliferative Disease With Primary Immunodeficiency (EBV+ PID LPD), EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (EBV+ AID LPD), EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous System (EBV+ CNS PTLD)
Register for Updates
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
NCT05366816
Recruiting
The purpose of this research is to test if mutations (changes in DNA) in exons (segment of DNA or RNA containing information that has the instructions for making proteins) in the KIT gene can be used to predict the body's response to standard of care treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/20/2023
Locations: University of Miami, Miami, Florida
Conditions: Gastrointestinal Stromal Tumors
Register for Updates
Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
NCT05766813
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Society (UKPDS) Brain Bank diagnostic criteria, who are experiencing wearing off symptoms and levodopa-induced dyskinesia.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
10/20/2023
Locations: Clinical Site, Miami, Florida
Conditions: Parkinson Disease
Register for Updates