There are currently 2028 clinical trials in Chicago, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Northwestern University, Rush University Medical Center, University of Chicago and University of Chicago Comprehensive Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study of PHST001 in Advanced Solid Tumors
NCT06840886
Recruiting
PHST001-101 is a multicenter, open-label, Phase 1 study of PHST001 in patients with advanced solid tumors. The study design includes a Dose Escalation Phase and a Dose Expansion Phase, and will enroll patients with advanced relapsed and/or refractory solid tumors. The study's primary object is to evaluate the safety and tolerability of PHST001 and determine the RP2D (Recommended Phase 2 dose) of PHST001.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Advanced Solid Tumors
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REDUCE Trial- Reducing Prolapse Recurrence
NCT04880239
Recruiting
This study will examine whether surgeons should add a prophylactic posterior colpoperineorrhaphy to a mesh-augmented apical prolapse repair.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Prolapse; Female
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Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
NCT05063331
Recruiting
The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2025
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Uterine Prolapse
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Childhood Activities Nutrition and Development Oversight
NCT05258656
Recruiting
The overall goal of this study is to understand how common conditions in childhood develop and if by providing specific health education and resources to parents/caregivers we can promote healthy development. This study will provide information and instruction on several aspects of infant care including, sleep, nutrition, building a healthy relationship with your baby, and healthy screen time use.
Gender:
ALL
Ages:
26 weeks and below
Trial Updated:
04/23/2025
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois +1 locations
Conditions: Environmental Exposure
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Potassium Citrate and Crystal Light Lemonade
NCT05389995
Recruiting
To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Kidney Stone
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ALS/MND Natural History Study Data Repository
NCT05966038
Recruiting
This is a data repository for multi-site multi-protocol clinic-based Natural History Study of ALS and Other Motor Neuron Disorders (MND). All people living with ALS or other MNDs who attend clinics at the Study hospitals (sites) are offered to participate in the Study. The Sites collect so-called Baseline information including demographics, disease history and diagnosis, family history, etc. At each visit, the Sites also collect multiple disease-specific outcome measures and events. The inform... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: ALS, PLS, MND (Motor Neurone DIsease), Kennedy Disease, PMA - Progressive Muscular Atrophy, PBP - Progressive Bulbar Palsy
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Surgical Approach to Uterine Septum
NCT06315582
Recruiting
The objective of this study is to determine if the use of scissors without electrosurgery is superior to bipolar electrosurgery for resection of uterine septum. The investigators will be comparing procedure-level variables such as operative time, complications, and need for additional procedures.
Gender:
FEMALE
Ages:
Between 22 years and 44 years
Trial Updated:
04/23/2025
Locations: Northwestern Medicine Prentice Women's Hospital, Chicago, Illinois
Conditions: Uterine Septum, Surgical Complication, Septum; Uterus, Treatment Side Effects, Treatment
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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
NCT06329401
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Progressive Pulmonary Fibrosis
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A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion
NCT06360354
Recruiting
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/23/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
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Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function
NCT06944392
Recruiting
This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Overactive Bladder (OAB)
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Conditioning SCID Infants Diagnosed Early
NCT03619551
Recruiting
The investigators want to study if lower doses of chemotherapy will help babies with SCID to achieve good immunity with less short and long-term risks of complications after transplantation. This trial identifies babies with types of immune deficiencies that are most likely to succeed with this approach and offers them transplant early in life before they get severe infections or later if their infections are under control. It includes only patients receiving unrelated or mismatched related dono... Read More
Gender:
ALL
Ages:
Between 0 years and 2 years
Trial Updated:
04/22/2025
Locations: Comer Children's Hospital/University of Chicago Medicine, Chicago, Illinois
Conditions: SCID
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Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
NCT06605118
Recruiting
This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo. Both groups also will receive standard of care preoperative antibiotics (excluding azithromycin). The primary endpoint is a maternal infection composite defined as any one of the following up to 6 weeks postpartum: endometritis, wound infection, abscess, septic thrombosis... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
04/22/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
Register for Updates