There are currently 1574 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
NCT02177578
Recruiting
In this study patients will be treated with 6 weeks of radiation therapy plus temozolomide chemotherapy according to the standard of care. However, the radiation treatment plan will be modified to deliver an higher than routine radiation dose to the subventricular zone which is an area of the brain that contains stem cells that some scientists believe may contribute to glioblastoma recurrence. The purpose of the study is to see if the tumor is controlled for a longer period of time in patients t... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/05/2024
Locations: The SKCCC at Johns Hopkins, Baltimore, Maryland
Conditions: Glioblastoma Multiforme
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Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases
NCT03223922
Recruiting
This is a trial that evaluates the preservation of cognition and neuropsychiatric function following genu-sparing whole brain radiation in patients with brain metastases.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/05/2024
Locations: The SKCCC at Johns Hopkins, Baltimore, Maryland
Conditions: Brain Metastases
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Functional Assessment in Liver Transplantation
NCT03228290
Recruiting
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive function. Subjects will again undergo assessments at every clinic visit through 12 months after transplant. Then, they will be followed annuall... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: End Stage Liver Disease
Register for Updates
Radiosurgical Hypophysectomy for Bone Metasteses Pain
NCT03377517
Recruiting
This research is being done to see if a delivery of a single high dose of radiation therapy to a small area of the pituitary gland and pituitary stalk in a highly precise manner may be helpful in reducing intractable pain from bone metastases.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/05/2024
Locations: The Sidney Kimmel Comprehsensive Cancer Center at Johns Hopkins, Baltimore, Maryland
Conditions: Bone Metastases
Register for Updates
Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
NCT05066113
Recruiting
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.
Gender:
All
Ages:
Between 22 years and 70 years
Trial Updated:
06/05/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Hidradenitis Suppurativa, Healthy Volunteers
Register for Updates
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
NCT06214923
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
06/05/2024
Locations: Luana Colloca, Baltimore, Maryland +1 locations
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
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Image-Guided Gynecologic Brachytherapy
NCT02993900
Recruiting
This research is being done to evaluate multimodality imaging, including magnetic resonance imaging-guided therapy (MRT), as a possible treatment for gynecologic cancers. The therapy takes place in the Department of Radiation Oncology at the Johns Hopkins SKCCC. The purpose of this study is to investigate the ability of MRI to successfully guide the placement of the brachytherapy applicator necessary to treat participants' gynecologic cancer. The Investigators want to see if the use of MRI will... Read More
Gender:
Female
Ages:
Between 18 years and 100 years
Trial Updated:
06/05/2024
Locations: The SKCCC at Johns Hopkins, Baltimore, Maryland
Conditions: Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, Bladder Cancer
Register for Updates
Chemosensory Dysfunction and Recovery in Endoscopic Endonasal Skull Base Surgery
NCT05912881
Recruiting
The investigators hypothesize that patients undergoing endoscopic endonasal skull base surgery experience clinically meaningful and modifiable disruptions in postoperative chemosensory function and quality of life, and the investigators further hypothesize that olfactory training in the postoperative period may significantly hasten normalization of patients' chemosensory perturbations. This tailored prospective study seeks to fulfill a significant gap in the understanding of the characteristics,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Anosmia, Skull Base Neoplasms
Register for Updates
DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma
NCT04248569
Recruiting
The primary objective of the trial is the safety and tolerability of administering a vaccine targeting the DNAJB1-PRKACA fusion kinase, in combination with nivolumab and ipilimumab in patients with unresectable or metastatic FLC and with non-FLC solid tumors and to assess the T-cell response.
Gender:
All
Ages:
12 years and above
Trial Updated:
06/05/2024
Locations: Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Fibrolamellar Hepatocellular Carcinoma (FLC)
Register for Updates
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension
NCT02682511
Recruiting
The purpose of this phase 2 multicenter, randomized, double-blind, placebo-controlled, study is to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic SSc (dcSSc) or SSc-associated pulmonary arterial hypertension (SSc-PAH).
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Scleroderma, Diffuse, Scleroderma, Systemic, Scleroderma, Limited, Sclerosis, Progressive Systemic, Skin Diseases, Connective Tissue Diseases, Pathologic Processes, Autoimmune Diseases
Register for Updates
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
NCT05658731
Recruiting
The goal of this trial is to determine whether it is possible to minimize radiation dose to parts of the brain that are important for thinking and learning in children who require radiation to treat their tumor, and if this will help reduce neurocognitive (thinking and learning) impairments in these patients. Patients with newly diagnosed brain or head and neck tumors who are having radiation therapy will have neurocognitive testing and MRI imaging (both research and for regular care) done as p... Read More
Gender:
All
Ages:
Between 1 year and 26 years
Trial Updated:
06/05/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Brain Tumor, Head and Neck Cancer
Register for Updates
Analysis of the Microbiome in Rosacea
NCT04108897
Recruiting
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy. This study was proposed to examine microbial signatures of the skin and gut microbiome in patients with moderate to severe rosacea and to identify differences between microbe communities in patients with rosacea and volunteers without rosacea using 16S ribosomal ribonucleic acid (rRNA) polymerase chain... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/05/2024
Locations: Cutaneous Translational Research Program, Department of Dermatology, Baltimore, Maryland
Conditions: Rosacea
Register for Updates