There are currently 2640 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Beth Israel Deaconess Medical Center and Brigham and Women's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)
NCT05658913
Recruiting
To collect Tau PET/CT imaging in older adults diagnosed with Mild Cognitive Impairment (MCI) or Alzheimer's Disease (AD) in the Mismatch Prospective Cohort Study (MPC-Tau) study to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the phenotypic variability of Alzheimer's Disease and other related pathologies.
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
08/13/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Alzheimer's Disease
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The PRECISION II Study: Evaluating the Accuracy of the LabPatch Glucose Sensing System
NCT05754281
Recruiting
The purpose of this study is to evaluate the accuracy of the Cambridge Medical Technologies, LLC second generation (2nd Gen) LabPatch glucose sensing system compared to a laboratory glucose analyzer (YSI 2300 STAT Plus) and 2 commercial glucometers, OneTouch Verio and Freestyle Lite. The primary endpoint of this study is the mean absolute relative difference (MARD) for 2nd Gen LabPatch system compared to each of the above mentioned glucose references over a 6 hour outpatient visit.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/13/2024
Locations: Joslin Diabetes Center, Boston, Massachusetts
Conditions: Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
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Treatment of Brain AVMs (TOBAS) Study
NCT02098252
Recruiting
The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of uncertainty. Management may include interventional therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in combination) or conservative management. The trial has been designed to test a) whether medical management or interventional therapy will redu... Read More
Gender:
ALL
Ages:
5 years and above
Trial Updated:
08/13/2024
Locations: Boston Medical Center, Boston, Massachusetts
Conditions: Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation, Arteriovenous Malformations, AVM, BAVM
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Child and Adolescent Registry for Participants With Narcolepsy
NCT04899947
Recruiting
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed. The study has 16 active clinical sites and a virtual site that widens participation to anywhere in the United States. For more information about the study or to access the Online Patient Enrollment System, visit the CATNAP website: https://catnap.healthie.net/welcome or email catnap@pulseinfoframe.com.... Read More
Gender:
ALL
Ages:
17 years and below
Trial Updated:
08/13/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy
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US National OCS Liver Perfusion (OLP) Registry
NCT05940857
Recruiting
This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted with United Network for Organ Sharing (UNOS) the Federal manager of the U.S. national transplant outcomes registry to obtain data that is routinely collected by the Organ Procurement and Transplantation Network (OPTN) on all transplanted organs in the U.S. for both the OCS liver transplanted patients as well as patients transplanted using o... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/13/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Liver Transplant
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Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
NCT06332144
Recruiting
The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: 1. whether children's statistical learning abilities can predict their long-term improvement of language and literacy skills in school; 2. how children's brains automatically learn patterns from speech and prints; 3. whether children's learning in th... Read More
Gender:
ALL
Ages:
Between 72 months and 90 months
Trial Updated:
08/12/2024
Locations: Northeastern University, Boston, Massachusetts +1 locations
Conditions: Autism Spectrum Disorder, Language Development, Literacy
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Individualized Vocational and Educational Support and Training for Clinical High Risk for Psychosis (InVEST)
NCT05114733
Recruiting
The purpose of this study is to test the efficacy of InVEST (Individualized Vocational and Educational Support and Training) for CHR-P (clinical high risk for psychosis) to address specific role functioning difficulties associated with the CHR-P phase. Our specific goals are: 1. Part 1: Preliminary open trial of InVEST (n = 8) to collect preliminary feasibility and acceptability data by providing the intervention, administering assessments, and collecting focus group and self-report feedback fr... Read More
Gender:
ALL
Ages:
Between 12 years and 22 years
Trial Updated:
08/12/2024
Locations: Beth Israel Deaconess Medical Center/ Massachusetts Mental Health Center, Boston, Massachusetts
Conditions: Clinical High Risk for Psychosis
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Testing a Transdiagnostic TMS Treatment Target
NCT06282146
Recruiting
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder. The main question is to understand the safety profile of a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation when it is targeting the posterior parietal cortex. Additional questions focus on whether this stimulation improves symptoms of depression and other psychiatric disorders as well... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/12/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders, Mental Disorder, Anxiety Disorders, OCD, PTSD
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AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC
NCT05632328
Recruiting
The goal of this research study is to asses the safety and efficacy of the combination of AGEN1423 and Botensilimab with or without chemotherapies, gemcitabine and nab-paclitaxel, for the treatment of advanced pancreatic ductal adenocarcinoma (PDAC) which has progressed after at least one previous line of cancer therapy. The names of the study drugs involved in this study are: * AGEN1423 * Botensilimab Participants will receive study treatment for about 2 years and will be followed for 1 year... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Advanced Pancreatic Ductal Adenocarcinoma, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer
Register for Updates
General Pre-Trial Screening Protocol for Infectious Diseases Research
NCT06463704
Recruiting
The purpose of this general screening protocol is to facilitate recruitment into studies conducted at the Center for Virology and Vaccine Research (CVVR) or Division of Infectious Diseases at Beth Israel Deaconess Medical Center. This general screening protocol will help to determine the eligibility of potential volunteers for any vaccine or therapeutic trials open for recruitment or soon to be opened.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Healthy Volunteers
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R-P NH of Genetic Vasculopathies
NCT06552052
Recruiting
This study will combine retrospective review of medical records from patients with ACTA2 and ongoing collection of clinical data using standardized instruments and intervals on an observational basis from patients with ACTA2. Patients in cohorts 1-3 will be asked to attend clinic visits in person per the schedule of events. At minimum, the medical records of patients with ACTA2 will be reviewed to record data on aspects of the disease, including disease characteristics and developmental milesto... Read More
Gender:
ALL
Ages:
29 days and above
Trial Updated:
08/12/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Multisystemic Smooth Muscle Dysfunction Syndrome
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MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
NCT05730816
Recruiting
In this research study, investigators will test whether prophylactic high-dose IV Mg administration attenuates the risk of AKI in patients with malignant mesothelioma receiving intraoperative chemotherapy (HIOC) with cisplatin compared to placebo .
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Mesothelioma
Register for Updates