There are currently 2781 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Beth Israel Deaconess Medical Center and Brigham and Women's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
Recruiting
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
Gender:
All
Ages:
22 years and above
Trial Updated:
06/24/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Aphakia
Artisan Aphakia Lens for the Correction of Aphakia in Children
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: Harvard University, Boston Children's Hospital, Boston, Massachusetts
Conditions: Aphakia
Dabrafenib + Trametinib + PDR001 In Colorectal Cancer
Recruiting
This research study is studying a combination of drugs as a possible treatment for metastatic colorectal cancer characterized by BRAF V600E mutation. The names of the study drugs involved in this study are: Dabrafenib Trametinib PDR001
Gender:
All
Ages:
18 years and above
Trial Updated:
06/24/2022
Locations: Massachusetts General Hosital Cancer Center, Boston, Massachusetts +1 locations
Conditions: Metastatic Colorectal Cancer
Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy
Recruiting
The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic cell transplant (HCT) after failure of rituximab.
Gender:
All
Ages:
All
Trial Updated:
06/23/2022
Locations: Dana Farber Cancer Institute, Brigham and Women's Hospital (Adults and Pediatrics), Boston, Massachusetts
Conditions: Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications
Evaluation of PET Probe [64]Cu-Macrin in Cardiovascular Disease, Cancer and Sarcoidosis.
Recruiting
To evaluate the safety of [64Cu] Macrin and its whole-body distribution, metabolism, pharmacokinetics, and radiation burden in healthy volunteers. To detect [64Cu]-Macrin accumulation in sites of disease in subjects with cancer, sarcoidosis or myocardial infarct.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/22/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Sarcoid, Cardiovascular Diseases, Cancer
Prevalence of Sleep Apnea and Atrial Fibrillation
Recruiting
The investigators will screen consecutive patients presenting to the atrial fibrillation clinic for sleep apnea using a FDA-approved home sleep testing device, WatchPAT to determine prevalence of sleep apnea in a clinic-based sample.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Sleep Apnea, Atrial Fibrillation
SCD vs. Mediterranean Diet Therapy in Ulcerative Colitis
Recruiting
Although patients and physicians have shown tremendous interest in the effect of diet on ulcerative colitis, there is a lack of significant evidence for providers to make practical recommendations with. In this study, the investigators hope to find out if dietary therapy by either the Specific Carbohydrate Diet (SCD) or the Mediterranean diet will help improve ulcerative colitis symptoms for patients with mild to moderately active disease. In addition, the investigators will compare disease acti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/27/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Ulcerative Colitis
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
Recruiting
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life. The goal is to develop a clinical survey that can improve the care of pediatric narcolepsy.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
05/26/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy, Obstructive Sleep Apnea
A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medications in Children With ADHD
Recruiting
This study will assess the efficacy of the text messaging (SMS-based) disease management intervention for children with Attention Deficit/Hyperactivity Disorder (ADHD) using the timeliness of stimulant prescription renewals over a 9-month period. Parents of participants in the study will receive customized text messages once a day, Sunday through Friday, for a duration of 9 months. The text messages will include reminders to adhere to the individualized medication regimen, reminders to call the... Read More
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
05/25/2022
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Attention Deficit/Hyperactivity Disorder
A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies
Recruiting
This is a Phase 1, open label, non-randomised, dose-escalation single agent study with expansion cohorts for dose confirmation/safety and preliminary efficacy of MCLA-145 in advanced or metastatic malignancies
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2022
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts
Conditions: Advanced Cancer, Solid Tumor, Adult, B-cell Lymphoma, Adult
Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy
Recruiting
The aim of the study is to assess the performance of Aquyre Biopsy Scanner technology (the FDA class I medical device) at determining if tissue from the lymph nodes and lung nodules, taken during a bronchoscopy procedure, is adequate for a diagnosis. The study will assess how well the Aquyre Biopsy Scanner can differentiate between tissue samples that meet certain requirements that allow for further diagnostic analysis and samples that do not.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2022
Locations: Boston Medical Center, Boston, Massachusetts
Conditions: Lung Cancer
Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing
Recruiting
This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago Medical Center. Study subjects will receive either a shared decision aid (SDA) about pain management or standard of care at the time of discharge. The impact of the SDA on the number of leftover opioid pills on postoperative day 30 and average NRS pain score on postoperative d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Knee Arthroplasty, Total, Analgesia, Opioid Use, Unspecified