There are currently 1090 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Use of a Squatting Assist Device in Patients with Constipation
NCT02877394
Recruiting
Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet. However, results from uncontrolled studies suggests that a squatting posture (as prevalent in many foreign countries) may be better at facilitating evacuation compared to a Western style commode. One uncontrolled, unpublished study suggests that a footstool improved bowel symptoms in nearly 98% of 153 constipated participants. Hence, the investigato... Read More
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Constipation
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Pain Control for Undergoing Costal Cartilage Harvesting
NCT05285566
Recruiting
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Nasal Surgery
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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People with Hairy Cell Leukemia (HCL)
NCT06561360
Recruiting
The researchers are doing this study to compare the safety of vemurafenib in combination with obinutuzumab to the standard of approach of cladribine in combination with rituximab. The researchers will look at which treatment causes fewer or milder side effects. Researchers think vemurafenib and obinutuzumab (non-chemotherapy drugs) may cause fewer side effects compared with the usual approach of chemotherapy drugs. They will also compare the two approaches to see which approach is more effective... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic Cancer Center, Rochester, Minnesota
Conditions: Hairy Cell Leukemia
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Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction
NCT05854303
Recruiting
The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Opioid-Induced Esophageal Dysfunction
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Optimizing Brain Stimulation Parameters
NCT06617845
Recruiting
A primary purpose of this study is to better understand what stimulation parameters work best for patients. For example, for Deep Brain Stimulation (DBS) of the Anterior Nucleus of the Thalamus (ANT), it is not clear what stimulation frequency leads is most effective. This study will help assess the effectiveness of low frequency or high frequency stimulation.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
09/27/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Epilepsy; Seizure
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Olorofim Aspergillus Infection Study
NCT05101187
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Invasive Aspergillosis
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Clinical Trial of Concomitant Hip Arthroscopy During PAO
NCT03181048
Recruiting
The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.
Gender:
ALL
Ages:
Between 15 years and 55 years
Trial Updated:
09/25/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Hip Dysplasia
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STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT05721248
Recruiting
This study is being done to see if anti-HER2 treatment be safely stopped in patients with HER2-positive metastatic breast cancer (MBC) that have had exceptional response to treatment. Exceptional response" is considered as cancer progression being controlled for three years or more since starting anti-HER2 treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Breast Cancer, Metastatic Breast Cancer, HER2-positive Breast Cancer
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Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
NCT06238648
Recruiting
This phase II trial compares epcoritamab to standard practice (observation) for the treatment of patients with B-cell lymphomas who are not in complete remission after treatment with CD19-directed chimeric antigen receptor T-cell (CAR-T) therapy. Epcoritamab is a bispecific antibody. It works by simultaneously attaching to a molecule called CD20 on cancerous B-cells and a molecule called CD3 on effector T-cells, which are a type of immune cell. When epcoritamab binds to CD20 and CD3, it brings t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Primary Mediastinal Large B-Cell Lymphoma, Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
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Ommaya Reservoir Placement for Brain Tumor Biomarker Access
NCT04692337
Recruiting
The purpose of this study is to determine the safety and feasibility of intra-operative Ommaya Reservoir placement during a clinically indicated operation for brain tumor. The Ommaya reservoir will facilitate a longitudinal access to cerebrospinal fluid (CSF) for analysis of potential biomarkers for brain tumor research and individualized monitoring.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Brain Tumor
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A Clinical Registry of Spontaneous Intracranial Hypotension
NCT05922514
Recruiting
The purpose of this research is to determine the efficacy of paraspinal vein embolization for treatment of digital subtraction myelography (DSM) or CT myelography (CTM) confirmed cerebrospinal fluid (CSF)-venous fistulas so that researchers can inform the development and design of future clinical trials of this technique.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Spontaneous Intracranial Hypotension
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A Prospective Research Investigation of Ischemia Using MCG
NCT06481943
Recruiting
PRISM is a prospective, pilot research study that aims to systematically characterize the usefulness of CardiAQ MCG, a bedside magnetocardiography device, in the evaluation of myocardial ischemia and infarction status.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Acute Coronary Syndrome
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