There are currently 1092 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients with Glioma
NCT06444412
Recruiting
This clinical trial evaluates whether gallium-68 (Ga-68) prostate specific membrane antigen (PSMA)-11 positron emission tomography (PET)/computed tomography (CT) imaging is useful in differentiating between disease that has come back after a period of improvement (recurrence) or that is growing, spreading, or getting worse (progression) and treatment effect in patients with glioma. Patients with glioma undergo frequent imaging for assessment of disease status. After first-line treatment however,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: WHO Grade 3 Glioma, WHO Grade 4 Glioma
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Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
NCT06557057
Recruiting
This study assesses the effect of hormone directed treatment for breast cancer on glucose metabolism.
Gender:
FEMALE
Ages:
All
Trial Updated:
09/19/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: HER2-Positive Breast Carcinoma
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Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes
NCT06607146
Recruiting
The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training in improving common measures of speech recognition and cochlear implant (CI) specific quality-of-life in new adult CI recipients in their first year post-activation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/19/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cochlear Implants, Bilateral Sensorineural Hearing Loss
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Beetroot Juice and Sleep
NCT05864521
Recruiting
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/18/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
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Study of Biomarker-Based Treatment of Acute Myeloid Leukemia
NCT03013998
Recruiting
This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with the ultimate goal of advancing new targeted therapies for approval. The study also includes a marker negativ... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/16/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Previously Untreated Relapsed Refractory Acute Myeloid Leukemia
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ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
NCT03911505
Recruiting
This is a Phase 3, open-label, multicenter study to evaluate the safety, PK, efficacy, PD, and immunogenicity of Cipaglucosidase Alfa/Miglustat treatment in enzyme replacement therapy (ERT)-experienced and ERT-naïve pediatric subjects with Pompe disease, aged 0 to \< 18 years
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
09/16/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pompe Disease (Late-onset)
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Remote Home-Based Exercise Program for Strength Training in Endometrial Cancer Survivors in Rural Areas
NCT06213571
Recruiting
This clinical trial studies how well a remotely delivered home-based exercise program for strength training works to positively impact endometrial cancer (EC) survivorship for patients with decreased cancer survivorship access. Cancer survivors in rural areas face barriers to supportive care, including geographic and environmental barriers to exercise and technology. Rural areas in the Midwest are underserved in terms of cancer care thus, it is essential to develop and test interventions that ar... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
09/12/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Stage IA Uterine Corpus Cancer AJCC v8, Stage IB Uterine Corpus Cancer AJCC v8
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Obstructive Sleep Apnea Among Somali-Americans
NCT04124848
Recruiting
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences. The investigators will compare Somali patients with known obstructive sleep apnea (OSA) to individuals without OSA, and to individuals of other ethnic/racial origins to determine the risk factors (genetic and/or physiologic) associated with developing cardiovascular diseases. This will help the investigators to understand the unique sleep pathology... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea
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Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery
NCT04730609
Recruiting
The purpose of this study is to determine the optimum dose of Dexmedetomidine to stop shivering in 90% of patients who experience shivering during scheduled elective cesarean deliveries.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Shivering, Dose Finding Study
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Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
NCT04938661
Recruiting
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/04/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention, Heart Failure
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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
ALL
Ages:
All
Trial Updated:
09/03/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
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Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
09/03/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
Register for Updates