New Hampshire is currently home to 323 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Lebanon, Manchester, Nashua and Portsmouth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults
NCT04219540
Recruiting
This study seeks to compare the effectiveness of two medications used to treat opioid use disorder, extended-release buprenorphine (XR-B) vs. extended-release naltrexone (XR-NTX), among adults currently incarcerated in U.S. jails and prisons at 5 distinct trial sites. This open-label, non-inferiority, head-to-head study design will offer providers, correctional and public health authorities, payers and policy makers' timely and relevant data to assess the effectiveness of XR-B (and XR-NTX) as po... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2024
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Opioid-use Disorder
Register for Updates
Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)
NCT06095583
Recruiting
The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use of toripalimab alone or in combination with tifcemalimab as consolidation therapy in patients with limited-stage small cell lung cancer without disease progression following chemoradiotherapy. Tifcemalimab is a monoclonal antibody against B and T lymphocyte attenuator (BTLA). Toripalimab is a monoclonal antibody against programmed death... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2024
Locations: Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Limited-stage Small Cell Lung Cancer (LS-SCLC)
Register for Updates
Detection and Delineation of Necrotizing Fasciitis Via a Vascular Perfusion Fluorophore
NCT04839302
Recruiting
The primary objective of this work is to determine if fluorescence signal intensity changes from a vascular perfusion fluorophore (indocyanine green) can be associated with the presence of necrotizing fasciitis. Hypothesis - Tissue regions affected with necrotizing fasciitis will demonstrate reduced fluorescence intensity compared to an unaffected region without clinical evidence of necrotizing fasciitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Dartmouth-Hitchock, Lebanon, New Hampshire
Conditions: Necrotising Fasciitis
Register for Updates
OCT in Open Fracture and Infected Fracture
NCT05785182
Recruiting
This is a pilot prospective, observational study of patients with open or infected fracture evaluating the feasibility and acceptability of OCT, a light-based imaging modality that requires no drug or contrast agent.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Trauma Injury, Trauma, Open Fracture, Fracture Infection
Register for Updates
MCI Speech in Noise
NCT06102486
Recruiting
The purpose of this study is to determine whether people with MCI (Mild Cognitive Impairment) and healthy comparison subjects differ with respect to their ability to hear soft sounds and how their brain understands and processes sound. The investigators are also evaluating, within those with MCI, whether the hearing tests are associated with neurocognitive functioning. The investigators are interested in learning whether changes in cognition in those with MCI can be detected using tests of how t... Read More
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
06/04/2024
Locations: Space Medicine Lab at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Mild Cognitive Impairment
Register for Updates
Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
All
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Children's Hospital at Dartmouth-Hitchcock, Lebanon, New Hampshire
Conditions: Bronchiolitis Acute Viral
Register for Updates
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
NCT05313165
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Register for Updates
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
All
Ages:
All
Trial Updated:
05/24/2024
Locations: Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Register for Updates
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
NCT06429280
Recruiting
Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%. The most common associated amblyogenic risk factors are uncorrected anisometropia, strabismus, or a combination of these. In addition to reduced visual acuity, amblyopic patients may also have measurable dysfunction of accommodation, fixation, binocularity, vergence, reading fluency, depth perception, and contrast sensitivity. For the first t... Read More
Gender:
All
Ages:
All
Trial Updated:
05/20/2024
Locations: Concord Eye Center, Concord, New Hampshire
Conditions: Amblyopia
Register for Updates
Early Chimerism Following Allogeneic Stem-Cell Transplant
NCT03689907
Recruiting
Allogeneic stem cell transplant (allo-SCT) is a common treatment for variety of blood cancers. To determine how much of your cells are from your donor after transplant, doctors complete a "chimerism analysis" or a test of your cells to look at the DNA. Chimerism testing helps doctors predict graft rejection or recurrence of disease. Doctors at NCCC do chimerism testing routinely and it is usually done between 30 and 100 days after transplantation. The researchers believe that analyzing chimerism... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Dartmouth Hitchcock Medical Center, Norris Cotton Cancer Center, Lebanon, New Hampshire
Conditions: Allogeneic Stem-Cell Transplant
Register for Updates
Heart Attack Research Program- Imaging Study
NCT02905357
Recruiting
The HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in patients with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each participant. Participants will be followed for recurrent clinical events, every 6 months, for a maximum of 10 years.
Gender:
All
Ages:
Between 21 years and 99 years
Trial Updated:
05/14/2024
Locations: Dartmouth-Hitchcock, Lebanon, New Hampshire
Conditions: Myocardial Infarction
Register for Updates
Internet Based Psychological Support
NCT02726061
Recruiting
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management. Together the three modules are called PATH. The problem-solving module is based on an evidence-based psychotherapy called Problem-Solving Therapy in which depressed patients identify problems in their lives and work through a structured format for solving these problems. We have subjected the problem-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Depression, Stress, Conflict Resolution
Register for Updates