Oregon is currently home to 1210 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study
NCT05608460
Recruiting
A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
11/01/2022
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Cervical Spine Fracture
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Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects
NCT01860612
Recruiting
The purpose of this study is to study the long term safety and effectiveness of an artificial iris prosthesis for the treatment of iris defects.
Gender:
ALL
Ages:
3 years and above
Trial Updated:
10/21/2022
Locations: Oregon Eye Associates, Eugene, Oregon
Conditions: Full Aniridia, Partial Aniridia
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CERENOVUS Neurothrombectomy Devices Registry
NCT05591183
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Cerebral Stroke
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Clinical and Genetic Analysis of ROP
NCT04420156
Recruiting
Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world. The investigators feel that this study will result in specific knowledge discovery about ROP, as well as general knowledge about how image-based data and genetic data can be combined to better understand clinical... Read More
Gender:
ALL
Ages:
1 year and below
Trial Updated:
04/18/2022
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Retinopathy of Prematurity
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Pilot Study of BCAA on Sleep
NCT03990909
Recruiting
Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health \& Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed to consume study product twice daily for 21 days. Self-report questionnaires, wrist actigraphy, pressure pain testing, and cognitive function will be assessed pre and post the experiment... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
04/04/2022
Locations: VA Portland Health Care System, Portland, Oregon
Conditions: Sleep Disorder, Traumatic Brain Injury
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Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans
NCT03968874
Recruiting
The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI). Secondarily, the project aims to identify blood-based brain biomarkers (BBBM) associated with sleep in Veterans. Specific Aim 1. Determine the effect of MBLT on sleep quality in Veterans (primary outcome). Specific Aim 2. Determine the effect of MBLT on downstream effectors of improved sleep, including cognition, mood, and quality of life... Read More
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
04/04/2022
Locations: Portland VA Medical Center, Portland, Oregon
Conditions: Traumatic Brain Injury
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Morning Bright Light to Improve Sleep Quality in Veterans
NCT03578003
Recruiting
One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders). Morning bright light therapy (MBLT) has been shown to improve sleep quality in a variety of conditions, but little has been done investigating the utility of MBLT in improving sleep in Veterans with TBI. This proposal aims to determine the effect of MBLT on sleep quality in Veterans with TBI. Vetera... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/04/2022
Locations: VA Portland Health Care System, Portland, Oregon
Conditions: Brain Injuries, Traumatic, Post-traumatic Stress Disorder
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Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis
NCT04833764
Recruiting
The goal of this study is to determine the safety and tolerability or efficacy of adjunctive treatments (including rosuvastatin 20 mg daily) in combination with standard anticoagulation therapy (Factor Xa inhibitors) in patients with lower extremity deep vein thrombosis (DVT). The efficacy of adjunctive treatments to prevent the development of post thrombotic syndrome (PTS) after DVT will be evaluated.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/14/2021
Locations: VA Portland Health Care System (VAPORHCS), Portland, Oregon
Conditions: Post-thrombotic Syndrome, Deep Vein Thrombosis Leg
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To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
NCT04816578
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: Kaiser Permanente - Northwest, Portland, Oregon
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
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Augmentation of Limb Perfusion With Contrast Ultrasound
NCT03195556
Recruiting
Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion. These observations have been made in mice with and without peripheral artery disease (PAD), and also in humans where high power contrast enhanced ultrasound (CEU) was used to measure perfusion but was found also to augment perfusion by almost 2-fold. The latter human studies were performed with ultrasound protocols designed for per... Read More
Gender:
ALL
Ages:
Between 19 years and 99 years
Trial Updated:
08/21/2018
Locations: OHSU, Portland, Oregon
Conditions: Peripheral Arterial Disease
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