Oregon is currently home to 1244 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest
NCT03079414
Recruiting
Sudden cardiac death (SCD) remains a major cause of mortality within developed nations despite aggressive efforts to reduce its societal burden. Despite extensive clinical and genetic investigations, a subgroup of cardiac arrests remain unexplained, highlighting the potential contribution of additional cardiac conditions that may not be identified with contemporary diagnostic algorithms. The EPS ARREST study aims to evaluate the role of invasive electrophysiology study within this patient popula... Read More
Gender:
All
Ages:
All
Trial Updated:
04/29/2022
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Sudden Cardiac Death
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Exercise in Pregnant Women With Gestational Diabetes
NCT04145479
Recruiting
Gestational diabetes (GDM) impacts 1 in 10 pregnancies; hyperglycemia and hypertriglyceridemia are common features of the condition. Women are recommended to do at least 150 minutes of moderate-intensity aerobic activity a week during pregnancy and the postpartum period. Exercise both during and out of pregnancy has been shown to be an effective non-pharmacologic tool to reduce glucose and lipid profiles. The goals and purpose of this pilot study is to 1) determine the influence of exercise and... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
04/27/2022
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Gestational Diabetes
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BFR Training on a Bike to Augment RC Strength, Leg Strength, and VO2 Peak
NCT05344391
Recruiting
This study will investigate if subjects who bike at 40% of heart rate reserve (HRR) with blood flow restriction (BFR) applied to bilateral thighs for 10 minutes (at 80% limb occlusion pressure) will experience greater gains in 10 rep max for dominant lower extremity leg press, greater gains in rotator cuff strength (hand held dynamometer testing for supraspinatus and external rotators) and greater gains in VO2 peak.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2022
Locations: College of Physical Therapy / George Fox University, Newberg, Oregon
Conditions: Can BFR Cycling Augment Strength and VO2peak
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Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer
NCT03753243
Recruiting
Pembrolizumab will be administered at a dose of 200 mg will be administered as a 30 minute IV infusion every 3 weeks. Enzalutamide will be administered at dose of 160 mg orally every day. All patients will be required to have at least one high-risk criteria.
Gender:
Male
Ages:
18 years and above
Trial Updated:
04/19/2022
Locations: VA Portland Healthcare System, Portland, Oregon
Conditions: Prostate Cancer
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Two Time a Week vs. Five Time a Week Blood Flow Restriction Training Program for the Lower Extremity.
NCT05342909
Recruiting
This study will randomize healthy adults who regularly perform resistance training exercises for the lower extremities (2x a week) to one of three groups: a blood flow restriction (BFR) exercise group that trains 2x a week, a BFR exercise group that trains 5x a week, and a control group that does not perform any additional BFR exercise. Those randomized to the BFR groups will perform the unilateral 90-0 knee extension exercise followed by the bilateral squat. Subjects will have the BFR applied t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2022
Locations: George Fox University School of Physical Therapy, Newberg, Oregon
Conditions: Blood Flow Restriction Training
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Clinical and Genetic Analysis of ROP
NCT04420156
Recruiting
Retinopathy of Prematurity (ROP) is a vascular disease affecting the retinas (back of the eye) of low birth weight infants. Although it can be treated effectively if diagnosed early, it continues to be a leading cause of childhood blindness in the United States and throughout the world. The investigators feel that this study will result in specific knowledge discovery about ROP, as well as general knowledge about how image-based data and genetic data can be combined to better understand clinical... Read More
Gender:
All
Ages:
1 year and below
Trial Updated:
04/18/2022
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Retinopathy of Prematurity
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Supracondylar Pinning Antibiotic Stewardship (SPAS) Trial
NCT04288206
Recruiting
Prospective, multi-center, randomized controlled trial studying infection rate with or without prophylactic antibiotics at the time of closed reduction and percutaneous pinning of pediatric supracondylar humerus fractures.
Gender:
All
Ages:
Between 0 years and 18 years
Trial Updated:
04/08/2022
Locations: Legacy Emanuel Medical Center, Portland, Oregon
Conditions: Supracondylar Humerus Fracture, Infection
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Pilot Study of BCAA on Sleep
NCT03990909
Recruiting
Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health & Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed to consume study product twice daily for 21 days. Self-report questionnaires, wrist actigraphy, pressure pain testing, and cognitive function will be assessed pre and post the experimenta... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/04/2022
Locations: VA Portland Health Care System, Portland, Oregon
Conditions: Sleep Disorder, Traumatic Brain Injury
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Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans
NCT03968874
Recruiting
The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI). Secondarily, the project aims to identify blood-based brain biomarkers (BBBM) associated with sleep in Veterans. Specific Aim 1. Determine the effect of MBLT on sleep quality in Veterans (primary outcome). Specific Aim 2. Determine the effect of MBLT on downstream effectors of improved sleep, including cognition, mood, and quality of life... Read More
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
04/04/2022
Locations: Portland VA Medical Center, Portland, Oregon
Conditions: Traumatic Brain Injury
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Morning Bright Light to Improve Sleep Quality in Veterans
NCT03578003
Recruiting
One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders). Morning bright light therapy (MBLT) has been shown to improve sleep quality in a variety of conditions, but little has been done investigating the utility of MBLT in improving sleep in Veterans with TBI. This proposal aims to determine the effect of MBLT on sleep quality in Veterans with TBI. Vetera... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2022
Locations: VA Portland Health Care System, Portland, Oregon
Conditions: Brain Injuries, Traumatic, Post-traumatic Stress Disorder
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OssiMend BA in Posterolateral Instrumented Lumbar Fusion
NCT04775537
Recruiting
The primary objective of this study is to measure the success rate of lumbar fusion in subjects at 12 months when instrumented lumbar arthrodesis is performed using OssiMend Bioactive Moldable as the bone grafting material
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2022
Locations: McKenzie-willamette Medical Center, Eugene, Oregon
Conditions: Spinal Disease, Degenerative Disc Disease
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Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
NCT02061436
Recruiting
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers. The information collected will be used to deter... Read More
Gender:
All
Ages:
All
Trial Updated:
03/08/2022
Locations: Providence Heart & Vascular Institute, Portland, Oregon
Conditions: Coronary Artery Disease
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