South Carolina is currently home to 1231 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Charleston, Greenville, Spartanburg and Columbia. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
In-Office Clinical Study of the Solo+ TTD
NCT05741333
Recruiting
The objective of this study is to evaluate the safety and effectiveness of the Solo+ Tympanostomy Tube Device (Solo+ TTD) for the placement of tympanostomy tubes in paediatric patients undergoing a tympanostomy procedure.
Gender:
All
Ages:
Between 6 months and 13 years
Trial Updated:
01/23/2024
Locations: South Carolina ENT, Columbia, South Carolina
Conditions: Ear Infection, Otitis Media
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Novel mGluR5 Modulator Effects on Alcohol Drinking and MRI Outcomes
NCT04831684
Recruiting
This study evaluates the effects of the medication GET73 among non-treatment-seeking individuals who regularly drink alcohol. Participants in the study will take GET73 or placebo for an 8-day study. There are 4 study visits including 2 MRI scans.
Gender:
All
Ages:
Between 21 years and 40 years
Trial Updated:
01/23/2024
Locations: Charleston Alcohol Research Center, Institute of Psychiatry, Medical University of South Carolina, Charleston, South Carolina
Conditions: Alcohol Use Disorder
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Modulating Anxious Coping
NCT04824105
Recruiting
This is a study to find out if a device that temporarily alters brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how people with anxiety or related concerns cope with feared or anxiety-producing situations. The study is recruiting people who recently started treatment for anxiety or a related concern. The study involves 3 visits to the Medical University of South Carolina. At the first visit, participants do interviews and surveys asking about anxiety a... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
01/23/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Anxiety Disorders
Register for Updates
Phase 3 Efficacy and Safety Laboratory Classroom Study in Pediatrics (6-12) With ADHD Using CTx-1301
NCT05924594
Recruiting
The goal of this clinical trial is to evaluate the efficacy and safety of CTx-1301 in children (6-12) with ADHD in a laboratory classroom setting.
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
01/22/2024
Locations: Coastal Carolina Research Center, North Charleston, South Carolina
Conditions: ADHD, ADHD - Combined Type, Attention Deficit Hyper Activity, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Hyperactivity Disorder Combined, Attention-deficit Hyperactivity
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Oral Nutritional Supplementation in Children at Risk of Undernutrition
NCT05161000
Recruiting
The objective of this randomized, controlled trial is to evaluate the effects of consuming a pediatric oral nutritional supplement (ONS) plus dietary counseling for 120 days on anthropometric growth, strength, and nutritional status, compared with dietary counseling alone in undernourished children in the United States.
Gender:
All
Ages:
Between 36 months and 107 months
Trial Updated:
01/22/2024
Locations: Tribe Clinical Research LLC., Greenville, South Carolina
Conditions: Undernutrition
Register for Updates
Symfony vs Vivity in Dim Light
NCT06229106
Recruiting
The purpose of this study is to evaluate the visual outcomes of the Symfony lens and the Vivity lens under mesopic lighting conditions in adult patients undergoing routine cataract surgery. Participants will be asked to read a visual acuity chart at different distances in dim light.
Gender:
All
Ages:
50 years and above
Trial Updated:
01/19/2024
Locations: Carolina Eyecare Physicians, LLC, Mount Pleasant, South Carolina
Conditions: Cataract
Register for Updates
RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study
NCT05202808
Recruiting
The primary objective of this study is to conduct a post-approval study which compares the LAL to a monofocal control IOL for safety outcomes.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
01/18/2024
Locations: Carolina Eyecare Physicians, LLC, Mount Pleasant, South Carolina
Conditions: Aphakia, Cataract
Register for Updates
Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With Dupilumab
NCT05694884
Recruiting
Multicenter, randomized, double-blind, placebo-controlled, parallel arm clinical study designed to evaluate the efficacy and safety of eblasakimab in participants with moderate-to-severe atopic dermatitis (AD) previously treated with dupilumab.The study consists of a 16-week treatment period and an 8-week follow-up period up to Week 24. Eligible participants will be randomized into one of the 2 treatment arms.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: ASLAN Investigative Site, Charleston, South Carolina
Conditions: Atopic Dermatitis
Register for Updates
Anesthetics and Analgesics in Children
NCT03427736
Recruiting
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
01/17/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Anesthesia, Pain
Register for Updates
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type
NCT05397639
Recruiting
This study will be conducted to evaluate the efficacy, safety, tolerability, and pharmacokinetics of masupirdine compared to placebo for the treatment of agitation in participants with dementia of the Alzheimer's type.
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
01/16/2024
Locations: Ralph H. Johnson VA Health Care System, Charleston, South Carolina
Conditions: Agitation, Alzheimer's Type Dementia
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Methocarbamol in Ventral and Inguinal HR
NCT05388929
Recruiting
The purpose of this study is to gather information on methocarbamol as a pain management treatment for ventral or inguinal hernia repair. Methocarbamol has been part of the pain management treatment for both inpatient and outpatient procedures at Prisma Health. This study will compare the outcomes of patients who receive methocarbamol, those who receive the standard opioid pain management treatment, and those who receive methocarbamol plus the standard opioid pain management treatment. Partici... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Prisma Health, Greenville, South Carolina
Conditions: Ventral Hernia, Inguinal Hernia
Register for Updates
A Study Assessing Corneal Endothelial Cells in Patients With Neovascular Age-related Macular Degeneration Treated With the Port Delivery System With Ranibizumab (PDS)
NCT04853251
Recruiting
This study will assess corneal endothelial cells in patients with neovascular age-related macular degeneration (nAMD) treated with Port Delivery System with ranibizumab (PDS) refilled every 24 weeks (Q24W)
Gender:
All
Ages:
50 years and above
Trial Updated:
01/16/2024
Locations: Palmetto Retina Center, LLC, West Columbia, South Carolina
Conditions: Neovascular Age-related Macular Degeneration
Register for Updates