There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Prospective Multi-Center Randomized Study for Evaluating the EVAHEART®2 Left Ventricular Assist System
NCT01187368
Recruiting
This is a prospective, multi-center, unblinded, randomized, controlled, and non-inferiority study comparing the EVA2 LVAS to the most recent magnetically levitated centrifugal LVAS (HM3 LVAS).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/20/2023
Locations: Baylor Scott and White, Dallas, Dallas, Texas
Conditions: Heart Failure
Register for Updates
The Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid Tumors
NCT04768868
Recruiting
A Phase 1 Dose Escalation and Expansion Study of IMP7068 Monotherapy in Advanced Solid Tumors
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2023
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Advanced Solid Tumors
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Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors
NCT04121442
Recruiting
Isunakinra - a potent Interleukin-1 receptor inhibitor - will be given to patients with solid tumors to determine safety and tolerability of three different doses. Isunakinra will then be combined with a PD-(L)1 inhibitor. Pharmacokinetics and Pharmacodynamic effects of monotherapy treatment as well as the combination will be evaluated.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/20/2023
Locations: Baylor Charles A. Simmons Cancer Center, Dallas, Texas
Conditions: Solid Tumor, Adult
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Comparison of a Novel Ultrasound System Versus Standard Imaging Modalities
NCT05748106
Recruiting
This is an observational study comparing a novel ultrasound-based imaging system (MAUI K3900) to standard-of-care (SoC) imaging systems used to guide and/or manage interventional radiologic procedures such as solid organ biopsies or lesion ablations.
Gender:
All
Ages:
All
Trial Updated:
02/17/2023
Locations: Texas Health Presbyterian Hospital, Dallas, Texas
Conditions: Image-Guided Biopsies and/or Ablations
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Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)
NCT01838512
Recruiting
The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2023
Locations: Local Institute, Dallas, Texas +4 locations
Conditions: Multiple Myeloma
Register for Updates
A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects
NCT03561259
Recruiting
The purpose of this study is to evaluate the efficacy and safety of 131I-MIBG in combination with Vorinostat in patients with Recurrent or Progressive neuroblastoma
Gender:
All
Ages:
1 year and above
Trial Updated:
02/15/2023
Locations: University of Texas Southwestern Medical Center, Children's Health, Dallas, Texas
Conditions: Neuroblastoma, Neuroectodermal Tumors, Neoplasms
Register for Updates
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
NCT05736029
Recruiting
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients. The investigators are going to search for correlation between specific biological features and response to immunotherapy, and to use those associations for developing an algorithm enabling to identify patients that could benefit from the immune check inhibitor based anti cancer treatment. Patients will provide biological samples before and during their treatment,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Baylor Scott and White Research Institute, Dallas, Texas
Conditions: Non Small Cell Lung Cancer, Healthy
Register for Updates
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
NCT01258231
Recruiting
This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.
Gender:
All
Ages:
Between 20 years and 90 years
Trial Updated:
02/06/2023
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery, Genetic Predisposition to Disease, Atrial Fibrillation, Myocardial Infarction, Heart Failure
Register for Updates
Cardiopulmonary Stress Testing (CPET) AlloSure Study
NCT04656080
Recruiting
Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ. (The implication of the null result would be that no restrictions to patient activity, nor modification of cardiac rehabilitation prescription, would be necessary to maintain proper test characteristics of AlloSure testing). In immunologically active cardiac transplant allografts, exercise prior to assay of do... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/25/2023
Locations: Baylor Scott & White health research institute, Dallas, Texas
Conditions: Heart Failure, Transplant; Failure, Heart
Register for Updates
The Hepatitis C Transplant Collaborative
NCT04493385
Recruiting
In this study we seek to test the hypothesis that safety and clinical outcomes after cardiac transplantation utilizing HCV NAT+ donor organs as currently performed are acceptable.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/25/2023
Locations: Baylor Scott & White Health Research Institute, Dallas, Texas
Conditions: Transplant; Failure, Heart, Hepatitis C
Register for Updates
Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study
NCT04496362
Recruiting
This single-center, open-label study will evaluate the safety and efficacy of subcutaneous heparin anticoagulation compared to the standard of care systemic intravenous anticoagulation during veno-venous extracorporeal membrane oxygenation for respiratory failure.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/25/2023
Locations: Baylor Scott & White Health research institute, Dallas, Texas
Conditions: ECMO, Heparin, Respiratory Failure
Register for Updates
Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research
NCT04664192
Recruiting
A major goal of this protocol is to support biomarker studies in advanced lung diseases, lung transplantation care, and to improve our understanding of the effects of viral and other infectious exposures to outcomes in our lung transplant and ALD patient populations.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2023
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Respiratory Failure, Interstitial Lung Disease, Lung Diseases
Register for Updates