There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Identify Proteomic Biomarkers for Outcome Prediction of Lipiodol TACE Treatment
NCT04459468
Recruiting
This study will enroll patients being planned for TACE, obtain blood samples pre and post TACE for biomarker identification using bead based X-aptamer library. No intervention is planned.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/18/2022
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Hepatocellular Carcinoma
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A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors
NCT05244551
Recruiting
This is an open-label phase 1 study with expansion. The study will start with a dose escalation of single-agent ABSK061 administered in repeated 28-day cycles in patients with advanced solid tumors to evaluate safety and tolerability. The expansion part will investigate oral ABSK061 at the recommended dose for expansion (RDE) to further evaluate safety and tolerability among selected tumor types. Preliminary antitumor activity will also be assessed.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2022
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Solid Tumor
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TruGraf® Long-term Clinical Outcomes Study
NCT04491552
Recruiting
This is a prospective, multi-center, observational study. Subjects will have OmniGraf™ (TruGraf® and TRAC™) testing at study enrollment and thereafter every 3 months. In addition subjects will have OmniGraf™ (TruGraf® and TRAC™) testing at any time there is a clinical suspicion of acute rejection. Data collection for the primary objective extends over a 2-year period.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/10/2022
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Kidney Transplant Rejection
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Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
NCT05614986
Recruiting
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2022
Locations: Baylor Heart and Vascular Hospital, Dallas, Texas
Conditions: Mild Cognitive Impairment, Aortic Stenosis
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Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study
NCT05608460
Recruiting
A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
11/01/2022
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Cervical Spine Fracture
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Improving Sleep Quality During Pregnancy Using an Oral Appliance
NCT03646214
Recruiting
Many pregnant women suffer from poor sleep quality and snoring. Evidence shows an increasing association between (1) sleep disordered breathing and (2) maternal cardiovascular disease and in-hospital death. Snoring is a variant of obstructive sleep apnea (OSA) and OSA during pregnancy is associated with higher risks for cesarean delivery, gestational hypertension, preeclampsia and preterm delivery. It may also impact fetal outcomes negatively. The purpose of this study is to determine whether sl... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
10/28/2022
Locations: Texas A&M University College of Dentistry, Dallas, Texas
Conditions: Snoring, Sleep Fragmentation
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Evaluation of the Clinical Impact of Corticosteroid Duration on SARS-CoV-2 (COVID-19 WHO)
NCT05595031
Recruiting
The purpose of this project is to evaluate the clinical impact of the use of glucocorticoids beyond 10 days for patients with critical COVID-19 at MDMC.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/21/2022
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Covid 19
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Coping, Perceived Meaning, Joy, Horizontal Civility at Work
NCT05595057
Recruiting
The aim of this study is to assess and describe employee characteristics associated with perceived horizontal inter-collegial workplace uncivil behavior within nursing services, and identify any relationships with meaning and joy in work (MJW), and assess job satisfaction.
Gender:
All
Ages:
All
Trial Updated:
10/21/2022
Locations: Methodist Dallas Medical Center, Dallas, Texas +2 locations
Conditions: Workplace Incivility, Joy, Self Efficacy
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Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
NCT03926624
Recruiting
Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting period per 28-day cycles. Control arm: Non-Intensive Reinduction (LoDAC, Azacitidine, Decitabine, Venetoclax Combination Regimens) or Intensive Reinduction (High and Intermediate Dose Cytarabine Regimens), dependin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/18/2022
Locations: UT Southwestern, Dallas, Texas
Conditions: Leukemia, Myeloid, Acute
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A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma
NCT05569057
Recruiting
This is a first in human, open-label, dose escalation and expansion Phase 1 study of SIM1811-03 in adult patients with advanced solid tumors and cutaneous T-cell lymphoma. SIM1811-03 is a first-in-class IgG1-based humanized anti-tumor necrosis factor type 2 receptor (TNFR2) monoclonal antibody for the treatment of malignant tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/03/2022
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Advanced Solid Tumor, Cutaneous T-cell Lymphoma (CTCL)
Register for Updates
Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention
NCT04375813
Recruiting
eRapa (encapsulated rapamycin) will be investigated for secondary prevention in patients with diagnosed non-muscle invasive bladder cancer (NMIBC) through a phase II double-blind randomized controlled trial of long-term (one year) prevention with eRapa versus placebo. The primary hypothesis is that eRapa decreases the risk of cancer relapse for patients with NMIBC. Secondary hypotheses are that eRapa can improve certain immune parameters and improve cognition and physical function without advers... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/14/2022
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Non-muscle Invasive Bladder Cancer
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Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
NCT05406167
Recruiting
The purpose of this prospective cohort study is to assess clinical and quality of life measures as well as to define the severity of adverse effects for the use of the RefleXion system to deliver intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT), in standard of care (SOC) use in the treatment of local,loco-regionally advanced, and oligometastatic malignancies. In addition, patient costs and charges will be analyzed to quantify the health economic impact of this modal... Read More
Gender:
All
Ages:
All
Trial Updated:
08/05/2022
Locations: UT Southwestern, Dallas, Texas
Conditions: Cancer, Cancer Central Nervous System, Cancer Thoracic, Cancer, Gastrointestinal, Cancer Gynecologic, Cancer, Genito-Urinary, Cancers Lymphatic, Cancer Head and Neck
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