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Depression Clinical Trials in Houston, TX
A listing of 22 Depression clinical trials in Houston, TX actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 22
The city of Houston, Texas, currently has 22 active clinical trials seeking participants for Depression research studies.
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
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GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Depression Clinical Trial
Recruiting
Join us in researching a potential investigational treatment for Depression. Reimbursement for study-related expenses may be available to you.
Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode forat least a month
Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode forat least a month
Conditions:
Depression
Major Depressive Disorder
Depressive Disorder
Depressive Symptoms
Depressive Disorder
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Recruiting
The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjunctive treatment of non-psychotic unipolar Major Depressive Disorder (MDD) in adults.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
04/29/2025
Locations: CHI St. Luke's Health Baylor College of Medicine Med. Ctr, Houston, Texas +1 locations
Conditions: Treatment Resistant Depression
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Recruiting
Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents. Although death by firearm remains the most common cause of suicide in the United States, an intentional overdose of substance usage such as prescription opioids accounts for over 5,000 suicides per year. In 2017, more than 70,000 drug overdose deaths occurred, making it the leading cause of injury-related death, and well over half (67.8%) inv... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
04/02/2025
Locations: The Menninger Clinic, Houston, Texas
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
Recruiting
Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Brain Health Consultants and TMS Center, Houston, Texas
Conditions: Treatment Resistant Depression
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
Recruiting
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of depressive episodes in bipolar disorder in adults, therefore pharmacotherapeutic options are limited. Given the change in disease state and safety demonstrated in adults with depressive episodes associate... Read More
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
03/24/2025
Locations: McGovern Medical School /ID# 240779, Houston, Texas +2 locations
Conditions: Depression, Bipolar I Disorder
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression
Recruiting
The purpose of the study is to assess the safety and acceptability of up to two sequential administrations of 25 mg psilocybin with additional therapeutic support in decreasing suicidality in patients with Bipolar Disorder (BD II) depression.
Gender:
ALL
Ages:
Between 25 years and 70 years
Trial Updated:
03/12/2025
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Bipolar II Disorder, Depression, Bipolar, Suicidality
Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story
Recruiting
The main goal of this research is to help families who are experiencing food insecurity (FI) and help mothers with depression.
The next goal is to provide other resources to help with household needs like rent or utility assistance, health insurance, anxiety, and depression. Our theory is that helping with food insecurity, household needs, and emotional health will help children and families.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Texas Children's Hospital, Houston, Texas
Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
Recruiting
This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels may be associated with an increased risk of dementia. Learning about the association between testosterone levels and risk of dementia may help determine the long-term effects of androgen deprivation therapy and may help improve quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
02/17/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Intracranial Investigation of Neural Circuity Underlying Human Mood
Recruiting
Depression is one of the most common disorders of mental health, affecting 7-8% of the population and causing tremendous disability to afflicted individuals and economic burden to society. In order to optimize existing treatments and develop improved ones, the investigators need a deeper understanding of the mechanistic basis of this complex disorder. Previous work in this area has made important progress but has two main limitations. (1) Most studies have used non-invasive and therefore impreci... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
02/11/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Depression, Epilepsy
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
Recruiting
To learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy on depression and/or anxiety in participants who are being treated for advanced cancer.
Gender:
ALL
Ages:
25 years and above
Trial Updated:
02/07/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Depression, Anxiety, Psilocybin-Assisted Psychotherapy, Advanced Cancer
Deep Brain Stimulation of Treatment-Resistant Bipolar Depression
Recruiting
This study is only enrolling at Baylor College of Medicine. The other research locations listed serve to support data analysis only.
This research study is to investigate the use of technology called Deep Brain Stimulation (DBS) to potentially improve Treatment-Resistant Bipolar Depression (TRBD) symptoms in patients with severe cases. DBS involves the surgical implantation of leads and electrodes into specific areas of the brain, which are thought to influence the disease. A pack implanted in... Read More
Gender:
ALL
Ages:
Between 22 years and 64 years
Trial Updated:
01/14/2025
Locations: Baylor College of Medicine, Houston, Texas +1 locations
Conditions: Bipolar Depression
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: The University Of Texas Medical School At Houston - UT Center Of Excellence On Mood Disorders, Houston, Texas +1 locations
Conditions: Treatment Resistant Depression
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD
Recruiting
Efficacy, Safety, and Tolerability of a single administration of COMP360 in participants with treatment-resistant depression (TRD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: UT Health Science Center at Houston (UTHSC-H), Houston, Texas
Conditions: Treatment Resistant Depression
1 - 12 of 22