Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome
NCT02094352
Terminated
The purpose of this study is to determine whether epidural and ketamine infusions are effective in the treatment of Complex Regional Pain Syndrome (CRPS).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/08/2018
Locations: Hospital for Special Surgery, New York, New York
Conditions: Complex Regional Pain Syndrome
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The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine
NCT02657031
Completed
This study compares the efficacy of low dose Ketamine versus Compazine for the control of headache in patients presenting to the Emergency Department.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/07/2017
Locations: University Medical Center of Southern Nevada, Las Vegas, Nevada
Conditions: Headache
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Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department
NCT01387139
Completed
The purpose of this study is to compare the effectiveness of the co-administration of intravenous ketamine and propofol to intravenous ketamine as a single agent for procedural sedation in the pediatric emergency department. The investigators hypothesize that patients receiving co-administration of ketamine and propofol will have a lower rate of adverse events, compared to patients receiving ketamine for procedural sedation.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
11/06/2017
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Procedural Sedation and Analgesia
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Ketamine in Colorectal Surgery
NCT02785003
Withdrawn
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain following open or laparoscopic colorectal surgery cases. Half of patients will receive the institutional standard of care and a placebo infusion (no active medication). The other half of patients will receive the institutional standard of care and a ketamine infusion. All subjects and staff will be blinded as to whether they are receiving placebo or ketamine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2017
Locations: Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin
Conditions: Acute Pain, Pain, Postoperative, Colorectal Surgery
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Ketamine: Comparison of IV Push vs. IV Drip
NCT02363270
Completed
Our previous published research comparing the efficacy of intravenous ketamine to morphine has shown ketamine to provide equivalent relief of moderate to severe acute pain in emergency medicine patients. Secondary analysis of the previous published research has also revealed ketamine to have statistically more side effects. The investigators believe that increasing the time of administration of the ketamine, from a push injection to a drip infusion, will minimize the side effects experienced by... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/19/2017
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Pain
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Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus
NCT02726867
Withdrawn
The purpose of the study is to evaluate the efficacy and safety of levetiracetam , lacosamide and ketamine treatment of refractory status epilepticus. This will be a randomized, open-label, four-arm pilot study comparing time to cessation of refractory status epilepticus, determined by continuous EEG monitoring, in patients with refractory status epilepticus. Patients with status epilepticus who have been treated with standard dose lorazepam (or midazolam) and ≥ 1000 mg phenytoin with documented... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/28/2017
Locations: MidAtlantic Epilepsy and Sleep Center, Bethesda, Maryland
Conditions: Epilepsy, Status Epilepticus
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Ketamine for Depression and Suicide Risk
NCT02094898
Completed
The purpose of this research study was to find out if the medication known as ketamine could help the symptoms of depression. This drug is approved by the U.S. Food and Drug Administration (FDA) as an anesthetic agent; however, it is not approved for use in depression treatment. The FDA allowed the use of this drug in this research study.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/10/2017
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Depression, Suicide
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Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
NCT00516503
Completed
RATIONALE: Baclofen-amitriptyline-ketamine (BAK) gel may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether BAK gel is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy . PURPOSE: This randomized phase III trial is studying BAK gel to see how well it works compared with a placebo in treating peripheral neuropathy caused by chemotherapy in patients with cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2017
Locations: Mayo Clinic Scottsdale, Scottsdale, Arizona +164 locations
Conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
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Immunomodulatory Properties of Ketamine in Sepsis
NCT01089361
Completed
The aim of the study is to assess the effect of short-term infusion of ketamine at analgesic dosage on the immune response, morbidity and mortality among patients suffering from septic shock. We hypothesize that ketamine will modulate the cytokine response to sepsis and reduce morbidity and mortality.
Gender:
ALL
Ages:
Between 21 years and 100 years
Trial Updated:
07/21/2017
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Sepsis
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Ketamine For Acute Treatment of Pain in Emergency Department
NCT02306759
Completed
The aim of the study is to compare the safety \& efficacy of low dose ketamine and morphine versus morphine alone for acute generalized pain in the Emergency Department (ED). The investigators are also interested to investigate whether low-dose ketamine is a safe and effective alternative option to opioids for the acute treatment of pain in the Emergency Department. The agents that are available in the department includes acetaminophen, non-steroidal anti-inflammatory (NSAIDS) and opioids. In m... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/11/2017
Locations: The Brooklyn Hospital Center, Brooklyn, New York
Conditions: Pain
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Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy
NCT00587665
Completed
Comparing patients receiving subanesthetic doses of Ketamine vs placebo to see if it can reduce narcotic needs for patients receiving a tonsillectomy and adenoidectomy
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
06/12/2017
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pain
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Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients
NCT01170247
Terminated
The purpose of this study is to determine if intranasal ketamine is equally as effective and safe as intramuscular ketamine for procedural sedation in pediatric patients.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
06/03/2017
Locations: University of Iowa Hospitals and Clinics, Iowa City, Iowa
Conditions: Sedation
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