Utah is currently home to 1240 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Salt Lake City, Murray, Ogden and West Jordan. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
NCT05183646
Recruiting
DMX-200 (repagermanium) is a C-C chemokine receptor type 2 (CCR2) inhibitor that, when administered concurrently with an ARB, is designed to inhibit recruitment of monocytes implicated in the inflammatory chemokine environment of chronic disease. The purpose of this pivotal randomized double-blind study is to investigate the efficacy and safety of DMX-200 120 mg twice daily (BID) compared with placebo over a treatment period of 104 weeks in adult patients with FSGS who are being treated with an... Read More
Gender:
All
Ages:
Between 12 years and 80 years
Trial Updated:
10/24/2023
Locations: ACTION3 Investigational Site 7, Salt Lake City, Utah
Conditions: FSGS
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Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)
NCT05172024
Recruiting
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals who will enter the cohort with and without SARS-CoV-2 infection and at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without Post-Acute Sequelae of COVID-19 (PASC) symptoms will be followed to identify risk factors and occurrence of PASC. This study will be conducted in the United States and subjects will be recruited through inpatien... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/24/2023
Locations: McKay-Dee Hospital, Ogden, Utah
Conditions: SARS-CoV2 Infection
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Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial
NCT02000115
Recruiting
The objective of the PORTICO pivotal IDE trial is to evaluate the safety and effectiveness of the St Jude Medical (SJM) Portico Transcatheter Heart Valve and Delivery Systems (Portico) in the treatment of severe symptomatic aortic stenosis via transfemoral and alternative delivery methods in high risk and extreme risk patients.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/24/2023
Locations: University of Utah Hospital, Salt Lake City, Utah
Conditions: Aortic Valve Stenosis
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Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)
NCT06105242
Recruiting
To identify biological sex differences in baseline RV function in CTEPH To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Intermountain Medical Center, Murray, Utah
Conditions: CTEPH
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An ACT Website for College Students With Insomnia
NCT06094751
Recruiting
College students experience higher rates of insomnia compared the general population, and accessibility and availability for the appropriate intervention is difficult due limited resources available to them in a college environment. Theorefore, it is vital to offer an intervention that can be just as effective yet more accessible than other available treatments targeting insomnia. That is why this study will investigate the efficacy and feasibility of an online ACT intervention for insomnia amon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/20/2023
Locations: Utah State University, Logan, Utah
Conditions: Insomnia
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Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence
NCT05634005
Recruiting
Determine whether clinical decision support (best practice advisory) improves provider adherence to transfusion guidelines for all four major blood components (red blood cells, plasma, platelets, and cryoprecipitate) using a randomized study design to reduce risk of bias. Alerts will be visible to the experimental ordering provider group, while they will not be visible to the control. Both groups still have access to information about best practices: local clinical transfusion guidelines are ava... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/20/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Anemia, Thrombocytopenia, Coagulopathy, Mild, Hypofibrinogenemia
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(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
NCT04910685
Recruiting
This is a randomized, double-blind, placebo-controlled, Phase 2/3 study comparing the efficacy and safety of BLU-263 + best supportive care (BSC) with placebo + BSC in patients with indolent systemic mastocytosis (ISM) whose symptoms are not adequately controlled by BSC. Parts 1 and 2 will enroll patients with ISM. Patients enrolled in Part 1 or Part 2 will roll over onto Part 3 to receive treatment with BLU-263 in an open-label fashion following completion of the earlier Part. Part M will enrol... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
10/20/2023
Locations: Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Conditions: Indolent Systemic Mastocytosis, Monoclonal Mast Cell Activation Syndrome
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Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: Cope Family Medicine/CCT Research, Bountiful, Utah
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Intermountain Medical Center, Murray, Utah
Conditions: Cutaneous Melanoma, Stage II
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IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
NCT03152058
Recruiting
This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will receive certolizumab, and pregnancy outcomes will be compared to those of women with APS and repeatedly positive tests for LAC enrolled... Read More
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
10/17/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: High Risk Pregnancy, Pregnancy Complications, Antiphospholipid Syndrome in Pregnancy, Lupus Anticoagulant Disorder
Register for Updates
A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
NCT04897945
Recruiting
Our goal is to test whether shared decision making for diabetes prevention can help women with a history of gestational diabetes mellitus (GDM) who are at high risk of developing type 2 diabetes (T2DM) increase weight loss and adoption of evidence based strategies to lower their risk of incident diabetes.
Gender:
Female
Ages:
Between 18 years and 54 years
Trial Updated:
10/10/2023
Locations: Intermountain Healthcare System, Salt Lake City, Utah
Conditions: Gestational Diabetes Mellitus, Pre-diabetes, Diabetes Mellitus, Type 2
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Circadian Intervention to Improve Cardiometabolic Health
NCT05943626
Recruiting
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD). Participants will undergo a randomized controlled trial, with circadian intervention and control (healthy lifestyle) groups. The circadian intervention is designed to reduce nighttime light exposure and after-dinner snack food intake. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, an... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
10/09/2023
Locations: College of Health Research Complex--University of Utah, Salt Lake City, Utah
Conditions: Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding, Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit, Sleep Hygiene
Register for Updates