Utah is currently home to 1235 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Salt Lake City, Murray, Ogden and West Jordan. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors
NCT04720976
Recruiting
To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Research Site, Salt Lake City, Utah
Conditions: Solid Tumor, NSCLC
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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
All
Ages:
15 months and below
Trial Updated:
05/15/2023
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
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Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
NCT05614115
Recruiting
The purpose of this study is to find out if empagliflozin, a new diabetic medication that has been shown to be very effective in lowering the risk of heart failure, is safe and tolerated in dialysis patients. In the recent years, empagliflozin has become a major tool to prevent heart failure hospitalization and to reduce the risk for cardiovascular death in diabetic and non-diabetic patients. Although patients with severe chronic kidney disease and ESKD have very high risk of heart failure and c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: End-stage Kidney Disease, Kidney Disease, Chronic, Dialysis, Diabetic, Non-diabetic, Kidney Dysfunction, Kidney Failure, Hemodialysis
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Intervention For AYAS With Cancer Risk Syndromes
NCT04323774
Recruiting
This research is being done because there is a need to improve cancer risk communication and decision-making among adolescents and young adults. In this study, the investigators are looking at whether using a chatbot and online portal for cancer risk information helps improve communication and decision-making. Over 70,000 adolescents and young adults (AYAs) are diagnosed with cancer in the U.S. every year and up to 10% have genetic changes (or, mutations) that put them at a higher risk of devel... Read More
Gender:
All
Ages:
Between 12 years and 24 years
Trial Updated:
05/09/2023
Locations: University of Utah, Huntsman Cancer Institute, Salt Lake City, Utah
Conditions: Cancer Risk Syndrome
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Sleep Technology Intervention to Target Cardiometabolic Health
NCT04766424
Recruiting
The goal of this study is to test the efficacy of a behavioral sleep extension intervention on sleep duration, cardio-metabolic disease risk factors, and health behaviors among adults with elevated blood pressure/hypertension and short sleep duration.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Elevated Blood Pressure, Habitual Sleep Duration of Less Than or Equal to 7 Hours
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A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors
NCT04868877
Recruiting
A phase 1/2 open-label multicenter study will be performed with an initial dose escalation part to determine the MTD and/or the RP2D of MCLA-129 as monotherapy in patients with NSCLC, HNSCC, GC/GEJ, ESCC, or other solid tumors and who have progressed after receiving prior therapy for advanced/metastatic disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2023
Locations: START Mountain Region, West Valley City, Utah
Conditions: Non-Small Cell Lung Cancer Metastatic, Gastric Cancer, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
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NETs: Protection or Harm in Neonatal Inflammation or Infection
NCT00747851
Recruiting
This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams) and PMNs from cord blood of healthy term infants will be isolated and stimulated with PAF, a biologically active phospholipid implicated in the pathogenesis of NEC. NEC, a disease of prematurity with an incidence of 10.1% of infants born weighing between 501 - 1500 grams... Read More
Gender:
All
Ages:
1 hour and below
Trial Updated:
05/05/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Necrotizing Enterocolitis (NEC)
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PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
NCT05128071
Recruiting
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily or placebo. The aims of this study are to assess the feasibility, safety and preliminary efficacy of micronized progesterone for the prevention of return to methamphetamine use. A secondary aim is to assess participant's salivary levels of allopregnanolone with methamph... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/04/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Methamphetamine-dependence, Postpartum Abstinence
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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
NCT04509050
Recruiting
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
Gender:
All
Ages:
5 years and below
Trial Updated:
05/04/2023
Locations: Primary Children's Cystic Fibrosis Center, Salt Lake City, Utah
Conditions: Cystic Fibrosis
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Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
NCT01099982
Recruiting
Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no inve... Read More
Gender:
All
Ages:
13 years and above
Trial Updated:
05/04/2023
Locations: Intermountain Medical Center, Murray, Utah
Conditions: Congestive Heart Failure
Register for Updates
Undergraduate Skin Cancer Prevention Trial
NCT05634252
Recruiting
The proposed study is a Multiphase Optimization Strategy (MOST) that uses factorial experiments to evaluate individual and combined effects of intervention components to improve intervention efficiency. The study team anticipates enrolling a total of 528 undergraduate students (>18 years) into the trial to identify intervention approaches that eliminate sunburn, and secondarily to motivate sun protection and discourage tanning. The study team will test personalized risk components: 1) UV Photo,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2023
Locations: Huntsman Cancer Institute, Salt Lake City, Utah
Conditions: Skin Cancer
Register for Updates
The Moran AMD Genetic Testing Assessment Study
NCT05265624
Recruiting
The goals of this study are: To assess the impact of genetic testing for Age-related Macular Degeneration (AMD) on lifestyle behaviors as measured by systemic and ocular carotenoid status.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
05/03/2023
Locations: University of Utah John A. Moran Eye Center, Salt Lake City, Utah
Conditions: Age-Related Macular Degeneration, Genetic Testing, Nutritional Biomarkers
Register for Updates