Vermont is currently home to 203 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Burlington, Bennington, Berlin and White River Junction. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Exercise Capacity Before and After AF Ablation in Patients With HFpEF
Recruiting
In a prospective, observational pilot study of patients scheduled for an atrial fibrillation (AF) ablation at the University of Vermont Medical Center the investigators will compare exercise capacity before and four months after AF ablation.
Gender:
All
Ages:
Between 18 years and 110 years
Trial Updated:
06/20/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
Pyridostigmine for the Treatment of Constipation in Parkinson Disease
Recruiting
Constipation is a common and debilitating non-motor symptom of Parkinson disease (PD) that often precedes the onset of classic motor symptoms by decades. There is no standardized algorithm for managing constipation in this patient population, nor are there dedicated treatments. Studies suggest that constipation can affect quality of life to a significant degree, in many cases just as much as motor symptoms. There is an unmet need for effective treatment options for constipation in this patient p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/15/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Parkinson Disease, Constipation
International CIPN Assessment and Validation Study
Recruiting
This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Chemotherapy-induced Peripheral Neuropathy, Quality of Life
Platelet FcGammaRIIa and Risk of Venous Thromboembolism in Cancer
Recruiting
Thrombosis is common and contributes significantly to morbidity and mortality in patients with cancer. At least 20% of patients with cancer develop venous thromboembolism (VTE) and another 5% will experience acute arterial thromboembolism (ATE) due to cancer and its treatment. Current guidelines recommend VTE thromboprophylaxis in high-risk outpatients. Thromboprophylaxis strategies are inadequate as 50% of high-risk patients on prophylaxis still develop a VTE, the rate of recurrent VTE is ~24%... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Venous Thromboembolism
Biomarkers of Independent Walking Post-Stroke
Recruiting
Prediction of walking recovery after stroke can inform patient-centered care and support discharge planning. The accuracy of current prediction models is limited, however, due to small study designs and narrow predictors assessed. The investigators propose a comprehensive evaluation of a novel combination of biomarkers to improve prediction of walking recovery and guide rehabilitation efforts after stroke. These include acute structural brain network disruption (utilizing MRI); blood biomarker l... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/10/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Stroke, Acute, Gait, Hemiplegic
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
Recruiting
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus as-needed rate control on the following outcomes: (1) exercise capacity, (2) AF burden, (3) symptomatic heart failure, (4) biomarker assessment of cardiac filling pressures and cardio-metabolic health, and (5) quality of life in patients with atrial fibrillation and stage... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy
Recruiting
With this pilot investigation, the investigators aim to challenge the reliance on opiate analgesia following colon and rectal surgery. Narcotic misuse and abuse is a pressing public health concern, and reduction in prescription rates could help to mitigate this issue. The goal of this pilot study is to establish feasibility of sufficient post-operative pain control after colectomy using non-narcotic analgesics. The investigators hypothesize that patients will be able to manage their post-operati... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/13/2022
Locations: UVM Medical Center, Burlington, Vermont
Conditions: Analgesia, Post-Operative Pain, Breakthrough Pain, Colectomy
USCRI Ready4Life Program
Recruiting
The U.S. Committee for Refugees and Immigrants (USCRI) has developed the Relationships, Education, Advancement, and Development for Youth for Life (READY4Life) Program. This is a 16-hour program for immigrants/refugees, ages 14 to 24. The program is designed to help young immigrants and refugees prepare for a successful life in the United States. The program is taught by USCRI program staff and is being implemented at eight sites across the U.S.: Cleveland, Ohio; Colchester, Vermont; Des Moines,... Read More
Gender:
All
Ages:
Between 14 years and 18 years
Trial Updated:
07/25/2022
Locations: USCRI Vermont, Colchester, Vermont
Conditions: Communication, Problem Solving, Social Relationships, Economic Stability
Intratumoral Cisplatin for Resectable NSCLC
Recruiting
PRIMARY OBJECTIVE: To identify the maximum tolerated dose (MTD) of intratumoral cisplatin, delivered during a single bronchoscopy with cone-beam CT confirmation, in a dose escalation protocol DESIGN: 3+3 dose escalation.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2022
Locations: University of Vermont, Burlington, Vermont
Conditions: Non-Small Cell Lung Cancer
Phase 1 Trial of Endobronchial Ultrasound-Guided Transbronchial Needle Injection of Cisplatin for Stage IV Lung Cancer
Recruiting
The goal of the study is to identify the maximum tolerated dose of endobronchial ultrasound-guided transbronchial injection (EBUS-TBNI) of cisplatin for Stage IV lung cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2022
Locations: University of Vermont, Burlington, Vermont
Conditions: Lung Cancer Metastatic
Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease
Recruiting
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2022
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Glomerular Disease, Proteinuria