Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease
Recruiting
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2022
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Glomerular Disease, Proteinuria
Web Based Orthopaedic Sports Medicine Registry
Recruiting
The purpose of this study is to establish an international, web based clinical registry to collect baseline characteristics of patients undergoing orthopaedic, sports medicine, arthroscopy, and related surgery, and the subsequent outcomes and cost-effectiveness associated with the surgical procedures and nonoperative treatments.
Gender:
All
Ages:
12 years and above
Trial Updated:
02/13/2022
Locations: Mansfield Orthopaedics, Waterbury, Vermont
Conditions: Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
Nutrition and Exercise in Critical Illness
Recruiting
This study proposes a novel early intervention combining Intravenous (IV) amino acids plus in-bed cycle ergometry exercise to improve physical outcomes in critically ill patients. The investigators hypothesize that this innovative approach will improve short-term physical functioning outcomes (primary outcome), as well as amino acid metabolism, body composition, and patient-reported outcomes at 6-month follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2021
Locations: University of Vermont College of Medicine, Burlington, Vermont
Conditions: Acute Respiratory Failure
Endoscopic Resection of Large Colorectal Polyps: An Observational Cohort Study
Recruiting
This protocol describes a prospective cohort study. It addresses an important challenge in the prevention of colorectal cancer: how to safely and effectively remove large polyps.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2021
Locations: White River Junction VAMC, White River Junction, Vermont
Conditions: Colonic Polyp, Colonoscopy, Complication, Recurrence
Cold Snare Endoscopic Mucosal Resection Trial
Recruiting
This study compares different approaches to endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps (≥20mm) in a 2 x 2 randomized design. The first randomization will assign half of patients to polyp resection with electrocautery ("hot" snare EMR) and half of patient to polyp resection without electrocautery ("cold" snare EMR). The second randomization will assign half of patients to polyp removal using Eleview as the submucosal injection agent, and the other half using pl... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2021
Locations: White River Junction VAMC, White River Junction, Vermont
Conditions: Colonic Polyp, Colonoscopy, Complication, Recurrence
Interim Buprenorphine Treatment to Bridge Waitlist Delays: Stage II Evaluation
Recruiting
Despite the demonstrated effectiveness of agonist treatment for opioid dependence and alarming recent increases in overdose deaths, waiting lists for treatment persist. In a Behavioral & Integrative Treatment Development pilot study, the investigators demonstrated the initial efficacy a novel Interim Buprenorphine Treatment (IBT) to mitigate the risks (e.g., illicit opioid use, IV drug use) associated with treatment delays. However, consistent with that R34 mechanism, our initial pilot study inv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2019
Locations: University of Vermont, Burlington, Vermont
Conditions: Opioid-use Disorder