West Virginia is currently home to 346 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)
Recruiting
This is a two-part study designed to evaluate the effect of Estetrol (E4) 15 or 20 mg, or placebo on the severity and frequency of vasomotor symptoms (VMS) (Efficacy Study Part) and the safety of E4 20 mg (Endometrial and General Safety Study Part)
Gender:
Female
Ages:
Between 40 years and 65 years
Trial Updated:
05/09/2022
Locations: Exemplar Research Inc, Morgantown, West Virginia
Conditions: Vasomotor Symptoms, Menopausal Symptoms
Use of Transmucosal Ketamine in Post Stroke Depression
Recruiting
Studies have shown that ketamine is very effective and has a quick onset in treatment of depression. Most of these studies used intravenous ketamine in an inpatient setting and there are no large trials examining its use in Post Stroke Depression (PSD). There have been only few studies that have used other routes of administration (i.e., oral, transmucosal, intranasal, intramuscular) of ketamine which provided symptom relief for depression. The purpose of this study is to assess the effectivenes... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2022
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: Post-stroke Depression
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
Recruiting
The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2022
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Locally Advanced Pancreatic Cancer
Longitudinal Performance of Epi proColon
Recruiting
This study will evaluate longitudinal performance of Epi proColon with respect to test positivity, longitudinal adherence to Epi proColon screening, adherence to follow-up colonoscopy and diagnostic yield, as well as assay failure rates.
Gender:
All
Ages:
Between 50 years and 74 years
Trial Updated:
10/29/2021
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Colorectal Cancer, Colorectal Neoplasms
Implementation of GLA:D Program in West Virginians With Osteoarthritis of the Knee
Recruiting
This study will examine feasibility of implementing Good Life with Osteoarthritis in Denmark (GLA:D) program in West Virginians with osteoarthritis of the knee
Gender:
All
Ages:
Between 45 years and 90 years
Trial Updated:
08/30/2021
Locations: School of Physical Therapy, Marshall University, Huntington, West Virginia
Conditions: Osteoarthritis, Knee
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Huntington, West Virginia
Conditions: Ulcerative Colitis
Convalescent Plasma Collection and Treatment in Pediatrics and Adults
Recruiting
This is a prospective study, involving contacting potential plasma donors and the use of their plasma to help fight off infections of those suffering from COVID19 in accordance to collection guidelines for plasma and FDA IND requirement. This study will include up to 240 participants potentially receiving convalescent plasma and up to 1000 potential donors. There are 3 basic arms to the study: mild, moderate and severe/critical severity. All 3 severity groups are eligible for enrollment, but mi... Read More
Gender:
All
Ages:
31 days and above
Trial Updated:
05/01/2020
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: COVID19, Coronavirus Infection, Coronavirus, Virus Diseases, RNA Virus Infections
Caris Biorepository Research Protocol
Recruiting
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/21/2020
Locations: CAMC Clinical Trials, Charleston, West Virginia
Conditions: Cancer
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Recruiting
Use of Muscle relaxant and reversal with Sugammadex at end of airway procedures will reduce the time to extubation after end of procedure
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2019
Locations: WVU Healthcare Ruby Memorial Hospital, Morgantown, West Virginia
Conditions: Microlaryngoscopy, Rigid Bronchoscopy
A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients
Recruiting
This is a proof-of-concept trial to compare 18F-FDG-PET/CT with NETSPOT (68Ga-DOTA-TATE), a commercially available radiotracer packet that utilizes 68Ga to image SSTR-specific tissue.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2019
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Head and Neck Squamous Cell Carcinoma