There are currently 2 active clinical trials seeking participants for Resistant Hypertension research studies. The states with the highest number of trials for Resistant Hypertension participants are Florida, California, Texas and Ontario.
A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension
Recruiting
This is a Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety, tolerability and the effect of 2 mg Baxdrostat vs. placebo, administered QD orally, on the reduction of SBP, measured by average 24-hour ABPM in 212 participants with rHTN (defined as seated SBP ≥ 140 mmHg at Screening and mean ambulatory SBP ≥ 130 mmHg at baseline, despite a stable regimen of ≥ 3 antihypertensive agents, one of which is a diuretic).
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
12/18/2024
Locations: Research Site, Surprise, Arizona +117 locations
Conditions: Resistant Hypertension
Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
Recruiting
African American adults in the United States have the highest prevalence rate of high blood pressure (hypertension) and heart failure in the world. African Americans with treatment resistant hypertension have higher levels of the enzyme - xanthine oxidase compared to Caucasians. This trial will test if administration of the xanthine oxidase inhibitor - Allopurinol (commonly used in the treatment of gout), given over a period of 8 weeks, will improve heart function, exercise ability and quality o... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/11/2024
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama
Conditions: Heart Failure Preserved Ejection Fraction, Resistant Hypertension