Georgia is currently home to 1949 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Atlanta, Augusta, Decatur and Savannah. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
NCT05766813
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Society (UKPDS) Brain Bank diagnostic criteria, who are experiencing wearing off symptoms and levodopa-induced dyskinesia.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/21/2024
Locations: Clinical Site, Augusta, Georgia
Conditions: Parkinson Disease
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Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
NCT02901184
Recruiting
Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is a unique Registry-Randomized Clinical Trial (RRCT) that will test the hypothesis that spironolactone plus standard of care compared to standard of care alone reduc... Read More
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
10/21/2024
Locations: Piedmont Atlanta Hospital, Atlanta, Georgia
Conditions: Heart Failure With Preserved Ejection Fraction
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Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients
NCT05866302
Recruiting
The study will have two separate patient cohorts: Cohort 1 will include patients with newly diagnosed chronic graft versus host disease (GVHD), whereas cohort 2 will include patients with newly diagnosed chronic lung disease (CLD). For cohort 1, the primary objective will be to characterize PRM metrics at the onset of chronic GVHD and determine if a PRM signature is present that will predict 1-year CLD free survival. For cohort 2, the primary objective will focus on characterizing PRM at the ons... Read More
Gender:
ALL
Ages:
36 months and above
Trial Updated:
10/15/2024
Locations: Emory University, Atlanta, Georgia
Conditions: Chronic Lung Disease, Hematopoietic Cell Transplantation, Graft Versus Host Disease
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Revealing Protective Immunity to Influenza Using Systems Immunology
NCT06501963
Recruiting
The goals of this study are to better understand the human immune response to influenza vaccines, specifically the live attenuated (weakened) influenza vaccine given as a nasal spray. Better understanding why this vaccine does not work as well in adults as it does in children may help design better influenza vaccines.
Gender:
ALL
Ages:
Between 18 years and 49 years
Trial Updated:
10/14/2024
Locations: Hope Clinic of the Emory Vaccine Center, Decatur, Georgia
Conditions: Influenza
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Spatial-Motor Stroke-Rehab Study
NCT06053320
Recruiting
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
10/11/2024
Locations: Emory Rehabilitation Hospital, Atlanta, Georgia
Conditions: Spatial Neglect, Stroke
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Disrupting Fear-based Memory Consolidation
NCT05560113
Recruiting
This project represents a unique collaborative opportunity to pursue the essential proof-of-principle demonstration that non-invasive interference of sensory cortical memory consolidation shortly after an emotional experience can attenuate the cued fear response and potentially reduce the risk of developing post-traumatic stress disorder (PTSD). If successful, the study results would anchor a potential advance in the treatment of patients after a traumatic event and seed future animal and clinic... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2024
Locations: Emory Rehabilitation Hospital, Atlanta, Georgia
Conditions: Post-Traumatic Stress Disorder
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Study Evaluating Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients w/ Locally Advanced or Metastatic HR+/HER2- Breast Cancer
NCT04851613
Recruiting
Study LAE205INT3101 is a Phase Ib/III study to evaluate the efficacy and safety of the combination therapy with afuresertib plus fulvestrant (afuresertib/placebo plus fulvestrant in Phase III) in patients with HR+/HER2- breast cancer who have failed 1 to 2 prior lines of endocrine therapy, and/or CDK4/6 inhibitor (up to 1 therapy), and/or chemotherapy (up to 1 chemotherapy) as described in the inclusion criteria.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Piedmont Cancer Institute, Atlanta, Georgia
Conditions: Breast Cancer
Register for Updates
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
NCT06100276
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Winship Cancer Institute of Emory University, Atlanta, Georgia
Conditions: Amyotrophic Lateral Sclerosis
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A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants with Generalized Anxiety Disorder (GAD)
NCT06051721
Recruiting
The purpose of this proof-of-concept trial is to examine the safety, tolerability, and pharmacokinetics (PK), and preliminary clinical efficacy of CYB004 participants with GAD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/08/2024
Locations: CenExel ACMR, Atlanta, Georgia
Conditions: Generalized Anxiety Disorder
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Influence of Fast and Slow Imagined Muscle Contractions on Muscle Function or Central Nervous System Properties
NCT06627491
Recruiting
The goal of this randomized clinical trial is to learn if imagining fast or slow muscle contractions causes different responses for nervous system excitability and muscle function in young, healthy males and females in. The main questions are: Does imagining fast muscle contractions cause greater nervous system excitability compared to imagining slow muscle contractions? Does imagining fast muscle contractions increase muscle function compared to imagining slow muscle contractions? A control... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
10/07/2024
Locations: Kennesaw State University, Kennesaw, Georgia
Conditions: Healthy
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First in Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients with Superficial Femoral Artery Disease And/or Proximal Popliteal Artery Disease
NCT06410313
Recruiting
This is a prospective, open label, multicenter, single arm, first in human clinical study. Patients with infra-inguinal peripheral arterial disease appropriate for treatment with a femoro-popliteal stent will be enrolled. The patients will be treated with the ChampioNIR Stent System. All implanted patients will be followed up at 30 days and 6, 12, 24 and 36 months. The follow-up visits will include patency evaluation by duplex ultrasound
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
10/04/2024
Locations: Piedmont Healthcare, Inc., Atlanta, Georgia
Conditions: Superficial Femoral Artery Stenosis, Popliteal Artery Stenosis
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Childhood Cancer Predisposition Study (CCPS)
NCT04511806
Recruiting
The Childhood Cancer Predisposition Study (CCPS) is a multi-center, longitudinal, observational study that will collect clinical and biological data and specimens from children with a cancer predisposition syndromes (CPS) and their relatives. The central hypothesis is that studying individuals at high risk for childhood cancer creates a unique opportunity for improving the understanding of carcinogenesis, tumor surveillance, early detection, and cancer prevention, which will collectively contri... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/03/2024
Locations: Children's Healthcare of Atlanta (CHOA), Atlanta, Georgia
Conditions: Pediatric Cancer
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