Ohio is currently home to 3204 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
NCT04771572
Recruiting
This is a Phase 1, multi-center, open-label study with a dose-escalation phase (Phase 1a) and a cohort expansion phase (Phase 1b), to evaluate the safety, tolerability, and PK profile of LP-118 under a once daily oral dosing schedule in up to 100 subjects.
Gender:
ALL
Ages:
13 years and above
Trial Updated:
04/23/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma, T-cell-prolymphocytic Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myeodysplastic Syndrome, Myelofibrosis, Myelodysplastic/Myeloproliferative Neoplasm, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Chronic Myelomonocytic Leukemia-2, Myelodysplastic Neoplasm in Blast Phase
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Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration
NCT02316379
Recruiting
The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Respiratory Disorders
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Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
NCT02272049
Recruiting
The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of children and adults and in adults and also in children with respiratory compromise due to a variety of diseases.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
04/23/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Respiratory Disorders
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Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation
NCT06056271
Recruiting
Observational, multi-center, clinical device registry for US patients with a primary goal to observe the clinical outcomes in patients who are mapped with Volta Medical's VX1 or AF-Explorer systems during AF ablation procedures.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/22/2024
Locations: Ohio State University, Columbus, Ohio
Conditions: Atrial Fibrillation
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Intravenous Oliceridine and Opioid-related Complications
NCT04979247
Recruiting
The investigator will evaluate the side effects of oliceridine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Cleveland Clinic Fairview Hospital, Cleveland, Ohio
Conditions: Major Surgery
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Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea
NCT04712656
Recruiting
The primary objective of this study is to determine whether the effect of continuous positive airway pressure (CPAP) therapy on 24-hour mean blood pressure (BP) in patients with obstructive sleep apnea (OSA) varies between symptom phenotypes.
Gender:
ALL
Ages:
Between 30 years and 75 years
Trial Updated:
04/19/2024
Locations: Martha Morehouse Medical Pavilion, Suite 2600, Columbus, Ohio
Conditions: Sleep Apnea, Obstructive
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Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures
NCT06111131
Recruiting
Demonstrate superiority of the Aspero Medical Ancora-SB balloon Overtube compared to the Olympus ST-SB1 Balloon Overtube.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/18/2024
Locations: The Ohio State University, Columbus, Ohio
Conditions: Small Bowel Disease
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Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants
NCT06063122
Recruiting
The goal of this clinical study is to test a new, novel medical device designed to improve speech sound differentiation among hospitalized preterm infants. The device is designed to be used at an age equivalent to 32 weeks of gestation or older and to integrate readily into clinical practice for use by nurses and therapists staffing Level II to Level IV NICUs. Preterm born infants are at high risk for neurosensory impairments and developmental delays. In the NICU, infants are often deprived of i... Read More
Gender:
ALL
Ages:
Between 32 weeks and 35 weeks
Trial Updated:
04/17/2024
Locations: Thrive Neuromedical, LLC, Chagrin Falls, Ohio
Conditions: Premature Birth
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Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery
NCT05659524
Recruiting
This is a prospective, single-blinded, multicenter study evaluating the benefit of sinonasal irrigations following endoscopic pituitary surgery. The goal of this study is to create practice changing guidelines with objective data highlighting the importance of irrigations on postoperative outcomes for pituitary surgery.
Gender:
ALL
Ages:
Between 19 years and 85 years
Trial Updated:
04/17/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Pituitary Tumor
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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
NCT05555589
Recruiting
The objective of this study is to compare the safety and efficacy of RGN-259 to placebo for the treatment of Neurotrophic Keratopathy (NK)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Neurotrophic Keratopathy
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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
NCT01656603
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Akron Children's Hospital, Akron, Ohio
Conditions: Infusion Reactions
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Cardiothoracic Critical Care as Subspecialty and Its Core Competencies
NCT06370338
Recruiting
The aim of this study is to develop a consensus on the curriculum for training cardiothoracic critical care by first evaluating the need for the field, based on a Delphi consensus among a panel of experts in this field.
Gender:
ALL
Ages:
All
Trial Updated:
04/16/2024
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Consensus Development
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